A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Allele Dmel\ac1

General Information
SymbolDmel\ac1SpeciesD. melanogaster
NameFlyBase IDFBal0000160
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\ac
Allele classhypomorph
Mutagenspontaneous
hide Nature of the Allele
Allele class
hypomorph
(Garcia-Bellido, 1979, )
Mutagen
spontaneous
(Campuzano et al., 1985)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Deletion for kb 84 to 64; includes y.
       
      A deficiency extending from a point between kb 64.9 and 63.5, which is approximately 5 kb upstream from the presumptive ac transcription unit, to the left to approximately kb 82. Deletion.
      (Campuzano et al., 1985)
      Assay mode
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      visible | recessive
      (Held, 1990)
      hide Phenotype Manifest In
      anterior dorsocentral bristle
       
      posterior dorsocentral bristle
       
      anterior supraalar bristle
       
      posterior supraalar bristle
       
      acrostichal bristle
       
      interocellar bristle
       
      interommatidial bristle
       
      mesothoracic tarsal bristle
      (Held, 1990)
      mesothoracic leg sensillum | ectopic
      (Held, 1990)
      hide Detailed Description
      Statement
      Reference
      Posterior dorsocentral bristles missing; also posterior supra-alar and anterior vertical bristles frequently missing. Anterior dorsocentrals displaced anteriorly (FBrf0020635). Garcia-Bellido (FBrf0033191) finds anterior dorsocentral bristles more strongly decreased than posterior dorsocentrals. Hairs usually fewer near position of posterior dorsocentrals; interocellar hairs invariably fewer, typically absent. Eyes partly devoid of hairs. Trichomes unaffected. Limited nonautonomy near the borders of somatic spots with respect both to numbers and positions of bristles and hairs (FBrf0009297; FBrf0013897; FBrf0020635).
       
      acHw-1/ac1 = acHw-1/+.
      (Sturtevant, 1970)
      The total number of bristles on the basitarsi of the second legs is reduced. The number of bractless bristles on the basitarsi remains normal. Significantly more bristles are missing from the anterior side of the basitarsus than from the posterior side. One or the other of the distal sensilla is sometimes missing, and an ectopic sensillum sometimes forms proximally between bristle rows 3 and 4.
      (Held, 1990)
      hide Interactions
      hide Phenotypic Class
      hideSuppressor of
      Statement
      Reference
      ac1/sc1 is a suppressor of visible | conditional ts phenotype of HC2.hs
      (Johannes and Preiss, 2002)
      hide Phenotype Manifest In
      hideNOT suppressed by
      Statement
      Reference
      ac1 has phenotype, non-suppressible by su(Hw)2
      (Lindsley and Grell, 1968)
      hideSuppressor of
      Statement
      Reference
      ac1 is a suppressor of phenotype of h1
      (Sturtevant, 1970)
      ac1/sc1 is a suppressor of wing vein | ectopic | conditional ts phenotype of HC2.hs
      (Johannes and Preiss, 2002)
      ac1/sc1 is a suppressor of wing | conditional ts phenotype of HC2.hs
      (Johannes and Preiss, 2002)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Complements
      ac3B
      (Garcia-Bellido, 1979)
      Comments
      hide Stocks ( 32 )
      Bloomington
      4181
      y1 ac1 v1
      7141
      y1 ac1 mxcG48/FM7a
      4596
      y1 ac1 sc1 pn1
      8715
      y1 ac1 w1118; P{GAL4-ac.13}1
      7135
      y1 ac1 z1 rtgG6/FM7c
      7137
      y1 ac1 z1 atxG1/FM7a
      7134
      y1 ac1 z1 rtgG44/FM7a
      7138
      y1 ac1 z1 elgG178/FM6
      7131
      y1 ac1 z1 Dsor1G42/FM7a
      6705
      y1 ac1 w1118; P{UAS.ey1-545.enRD}UEE3
      Kyoto
      101237
      y1 ac1 wa ec1
      107816
      y1 ac1 sc1 pn1
      hide Notes on Origin
      Discoverer
      Weinstein, 3rd Feb. 1916.
      Arose on: yunspecified.
       
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      ac1
       
      sc11
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 10 )
        Research paper
        Johannes and Preiss, 2002, Mech. Dev. 115(1-2): 3--14
        Wing vein formation in Drosophila melanogaster: hairless is involved in the cross-talk between Notch and EGF signaling pathways. [FBrf0149093]
        Held, 1990, Roux Arch. dev. Biol. 199(1): 48--62
        Arrangement of bristles as a function of bristle number on a leg segment in Drosophila melanogaster. [FBrf0052925]
        Campuzano et al., 1985, Cell 40: 327--338
        Molecular genetics of the achaete-scute gene complex of D. melanogaster. [FBrf0042024]
        Garcia-Bellido, 1979, Genetics 91: 491--520
        Genetic analysis of the achaete-scute system of Drosophila melanogaster. [FBrf0033191]
        Sturtevant, 1970, Dev. Biol. 21: 48--61
        Studies on the bristle pattern of Drosophila. [FBrf0021409]
        Dubinin, 1933, J. Genet. 27: 443--464
        Step-allelomorphism in Drosophila melanogaster. [FBrf0002571]
        Dubinin, 1930, Zh. eksp. Biol. Med. 6: 325--346
        A study of step-allelomorphism. [FBrf0002112]
        Weinstein, 1918, Genetics 3: 135--173
        Coincidence of crossing over in Drosophila melanogaster (ampelophila). [FBrf0000909]
        Review
        Simpson et al., 1993, Ingham, Brown, Martinez Arias, 1993: 29--39
        A dual role for the protein kinase shaggy in the repression of achaete-scute. [FBrf0074460]
        Book
        Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
        Genetic variations of Drosophila melanogaster. [FBrf0020044]