FlyBase Allele Report: Dmel\Antp[50]

General Information

Symbol

Dmel\Antp⁵⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0000569

Feature type

allele

Associated gene

Dmel\Antp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

gain of function allele

Mutagen

X ray

Nature of the Allele

Allele class

gain of function allele

Mutagen

X ray

(Scott et al., 1983)

Progenitor genotype

Caused by aberration

Dp(3;3)Antp⁵⁰

Cytology

Description

Duplication breakpoints ate at map position +161.

(Scott et al., 1983)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Scott et al., 1983)

visible | homeotic

Phenotype Manifest In

antenna

(Scott et al., 1983, Lewis et al., 1980)

leg | ectopic

(Scott et al., 1983)

Detailed Description

Statement

Reference

Antennae to leg transformation.

(Scott et al., 1983)

Transformation of antenna to prothoracic leg identity.

(Lewis et al., 1980)

Variable transformation of entire antenna into a leg may occur, but effect is often limited to slight elongation of third antennal segment. In compounds with Pc and Pc², the rather well-developed antennal second legs show some transformation into first legs (Hannah-Alava, quoted in FBrf0020044). Lethal in combination with Antp^B, Antp^Yu, Antp⁴⁹, and Scr (Hannah-Alava, quoted in FBrf0020044). RK3A.