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General Information
Symbol
Dmel\AntpB
Species
D. melanogaster
Name
of Bacon
FlyBase ID
FBal0000580
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Inversion breakpoint is 10.5kb upstream of the P2 cap site.
Distal inversion breakpoint is at map position +138.
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Heterozygous adults show transformation of antenna to leg.
Partial transformation of antennae into legs. Flies exhibit diminished chemosensory jump behaviour to ethyl acetate but no change in the jump response to a visual stimulus.
Homeotic transformation of antennae to mesothoracic legs.
Enhanced by ph-d2.
Antennae to leg transformation.
Transformation of antenna to prothoracic leg identity.
Antenna are leg-like.
Antenna partially leglike but less extreme than AntpYu and may overlap wild type. Enhanced by Pc. Enhanced by Pc2. Enhanced by ssa. AntpB ssa/+ ssa has virtually complete antennal leg including coxa, tibia, femur, and tarsus but no sex comb in the male (B. Holloway, cited in FBrf0020044). RK3A.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference
AntpB has phenotype, enhanceable by art1
Other
Additional Comments
Genetic Interactions
Statement
Reference
The frequency of antenna-to-leg transformation seen in AntpB heterozygotes is increased by expression of Glut4EFd.Scer\UAS under the control of Scer\GAL4Glut4EF-NP7418.
Homeotic transformation of antennae to T2 leg seen in AntpB flies can be redirected by pbhs.PB from ectopic leg to maxillary palp.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
Bacon, July 1950.
Comments
Comments
The wing positioning defects in In(3R)AntpB flies were previously attributed to an effect on Antp (FBrf0107412 and FBrf0155711), however, FBrf0204343 demonstrates that these phenotypes are instead due to an effect on Glut4EF, which is also disrupted by the In(3R)AntpB chromosome.
FlyBase curator comment: FBrf0155711 attributes the wing positioning defects in In(3R)AntpB flies to an effect on Antp. However, FBrf0204343 demonstrates that the Glut4EF gene is also disrupted by the In(3R)AntpB chromosome, and that the wing positioning defects seen are instead due to an effect on Glut4EF.
FlyBase curator comment: FBrf0107412 attributes the wing positioning defects in In(3R)AntpB flies to an effect on Antp. However, FBrf0204343 demonstrates that the Glut4EF gene is also disrupted by the In(3R)AntpB chromosome, and that the wing positioning defects seen are instead due to an effect on Glut4EF.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
of Bacon
Secondary FlyBase IDs
    References (22)