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General Information
Symbol
Dmel\Asx1
Species
D. melanogaster
Name
FlyBase ID
FBal0000784
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
AsxIIF51
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Shows no dominant effect on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w+mW.hs allele at the telomeres of the second and third chromosomes.

Dominantly enhances position effect variegation (PEV) at the w locus caused by In(1)wm4, PEV at the B locus caused by Dp(1;Y)BSCV and PEV at the Sb locus caused by T(2;3)SbV.

Asx1/+ ; Df(3L)fz-GS1a embryos completely lack the head, thorax and ventral denticle belts.

Embryonic lethal or semi-lethal when heterozygous with ph-d2. Unhatched larvae carry segmentation defects or polarity defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

Asx[+]/Asx1 is an enhancer of visible phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

NOT Enhancer of
Statement
Reference

Asx[+]/Asx1 is a non-enhancer of visible phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Suppressor of
Statement
Reference

Asx[+]/Asx1 is a suppressor of visible | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

Asx[+]/Asx1 is a suppressor of visible phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4GMR.PU

Asx[+]/Asx1 is a suppressor | partially of visible phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4ptc-559.1

NOT Suppressor of
Statement
Reference

Asx[+]/Asx1 is a non-suppressor of visible phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Phenotype Manifest In
Enhancer of
Statement
Reference

Asx[+]/Asx1 is an enhancer of wing phenotype of E2f1UAS.cNa, Scer\GAL4Act88F.PD

Asx[+]/Asx1 is an enhancer of eye phenotype of Hsap\MECP2UAS.FL, Scer\GAL4GMR.PU

Asx[+]/Asx1 is an enhancer of eye phenotype of Hsap\MECP2Δ166.UAS, Scer\GAL4GMR.PU

Asx1 is an enhancer of sex comb phenotype of Pc4

NOT Enhancer of
Statement
Reference

Asx[+]/Asx1 is a non-enhancer of eye phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Asx1 is a non-enhancer of eye phenotype of CycEJP

Suppressor of
Statement
Reference

Asx[+]/Asx1 is a suppressor of eye phenotype of E2f1dsRNA.UAS.cJa, Scer\GAL4GMR.PU

Asx[+]/Asx1 is a suppressor of wing vein | ectopic phenotype of Snr1E1

NOT Suppressor of
Statement
Reference

Asx[+]/Asx1 is a non-suppressor of eye phenotype of DpUAS.cDa, E2f1UAS.cNa, Scer\GAL4GMR.PU

Asx1 is a non-suppressor of eye phenotype of CycEJP

Additional Comments
Genetic Interactions
Statement
Reference

The formation of ectopic wing veins observed in adult flies expressing Marcal1Scer\UAS.cBa under the control of Scer\GAL4tub.PU is ameliorated by combination with a single copy of Asx1.

Asx1/Snr1E1 wings have an extra vein between veins L3 and L4 in 11% of cases.

Enhances the trx-G homeotic transformations of Df(3R)red1. Strongly enhances the extra sex comb phenotype of Pc4.

The addition of heterozygous Asx1 can suppress the Pairing sensitive silencing effect seen in wMcp.scs'.11. The addition of heterozygous Asx1 has no effect on the Pairing sensitive silencing effect seen in wMcp.10, wMcp.11, wMcp.13, wMcp.scs'.14 and wMcp.scs'.12:15. The addition of heterozygous Asx1 has no effect on the Pairing sensitive silencing effect seen in wMcp.scs'.11 (P{Mcp-w#11}16/+, P{Mcp-w#11}102/+) double heterozygous insertions. The addition of heterozygous Asx1 has no effect on the Pairing sensitive silencing effect seen in wMcp.scs'.14/ wMcp.13 (P{Mcp-w#14}AP-2stummelbein/+, P{Mcp-w#13}116/+) double heterozygous insertions.

Xenogenetic Interactions
Statement
Reference

The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1Scer\UAS.cBa under the control of Scer\GAL4Bx-MS1096 is ameliorated by combination with a single copy of Asx1.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Isolated as an embryonic lethal mutation causing head defects.

Weak derepression of en expression.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (22)