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General Information
Symbol
Dmel\Asx5
Species
D. melanogaster
Name
FlyBase ID
FBal0000788
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
AsxD1
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

denticle belt & thorax

Detailed Description
Statement
Reference

Embryos doubly mutant for PscArp.1 and Asx5 show strong posteriorly directed segmental transformations; in most embryos the thoracic ventral setal belts (VSBs) resemble typical abdominal VSBs, and from two to eight VSBs have a typical A8 shape. Many embryos have abdominal-like VSBs on the head.

Abdominal type denticles appear in the ventral setal belts of the thoracic segments. With respect to the degree of transformation to more posterior structures, Df(2R)trix/Df(2R)trix > Df(2R)trix/Asx5 > Asx5/Asx5, indicating that Asx5 is hypomorphic mutation. Similar genotypes derived from Df(2R)trix/Asx5 oocytes achieved by means of pole-cell transplantation display more severe transformation than their counterparts above derived from mothers carrying one dose of Asx+.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

Asx5 is an enhancer of phenotype of Pc3

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

recovered as suppressor of Pc

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Duncan.

Comments
Comments

Ectopic abd-A is present in parasegments 2-6 in the epidermal cells. Abd-B shows a graded expression at 9 hours along the A-P axis, more concentrated in the posterior. By 12 hours the expression is more uniform.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (7)