FlyBase Allele Report: Dmel\baz[4]

General Information

Symbol

Dmel\baz⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0001024

Feature type

allele

Associated gene

Dmel\baz

Associated Insertion(s)

Carried in Construct

Also Known As

baz^Xi106, baz^Xi, baz^XJ106

Genomic Maps

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Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Tearle and Nusslein-Volhard, 1987)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

point mutation

X:17,189,991..17,189,991 [+]

Nucleotide change:

C17189991T

Amino acid change:

Q374term | baz-PA; Q395term | baz-PB; Q374term | baz-PC; Q395term | baz-PD

Reported amino acid change:

Q374term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Krahn et al., 2010)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

Amino acid replacement: Q374term.

(Krahn et al., 2010)

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of cancer

CEA with Ras85D^V12.UAS

(Pagliarini and Xu, 2003)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

actomyosin

(David et al., 2010)

adherens junction

(Bilder et al., 2003)

adherens junction | pupal stage | somatic clone

(Zaessinger et al., 2015)

amnioserosa

(David et al., 2010)

border follicle cell, with Scer\GAL4^slbo.2.6, baz^{dsRNA.Sym.UAS}

(Pinheiro and Montell, 2004)

border follicle cell | somatic clone

(Pinheiro and Montell, 2004)

bouton

(Ruiz-Canada et al., 2004)

embryo | dorsal

(Tearle and Nusslein-Volhard, 1987)

embryo | gastrula stage

(Campbell et al., 2009)

embryo | ventral

(Tearle and Nusslein-Volhard, 1987)

embryonic/first instar larval cuticle

(David et al., 2010, Harris and Peifer, 2005, Bilder et al., 2003, Tanentzapf and Tepass, 2003)

embryonic/first instar larval cuticle | germline clone

(Wodarz et al., 2000)

embryonic/first instar larval cuticle | ventral

(Wodarz et al., 2000)

embryonic/larval cuticle

(Shao et al., 2010)

embryonic epidermis

(Muller and Wieschaus, 1996)

embryonic ganglion mother cell | germline clone

(Wodarz et al., 1999)

embryonic head

(Wodarz et al., 2000)

embryonic Malpighian tubule

(Campbell et al., 2009)

embryonic neuroblast & spindle | germ-line clone

(Wodarz et al., 1999)

epithelial cell | germline clone

(Wodarz et al., 2000)

eye | somatic clone

(Hong et al., 2003)

eye disc | pupal stage

(Zaessinger et al., 2015)

eye photoreceptor cell & eye disc & pupa | somatic clone

(Hong et al., 2003)

eye photoreceptor cell & eye disc & pupa | somatic clone | cell non-autonomous

(Hong et al., 2003)

follicle cell | somatic clone

(Pinheiro and Montell, 2004)

neuroblast | P-stage | somatic clone

(Cai et al., 2003)

ommatidium | somatic clone

(Hong et al., 2003)

photoreceptor cell & eye | somatic clone

(Hong et al., 2003)

presumptive embryonic/larval nervous system

(Bayraktar et al., 2006)

spot adherens junction

(Harris and Peifer, 2004)

zonula adherens

(Muller and Wieschaus, 1996)

Detailed Description

Statement

Reference

Homozygous clones in the wing disc survive and do not show polarity defects.

(Padash Barmchi et al., 2016)

Somatic clones of baz⁴ homozygous mutant cells in the pupal eye disc show extra inter-ommatidial cells and increased frequency of disruptions in the structure of adherens junctions.

(Zaessinger et al., 2015)

Centrosome asymmetry during cytokinesis in mutant pI (sensory organ precursor) cells in the notum is identical to that seen in wild-type pI cells.

(Jauffred et al., 2013)

Mutant egg chambers show a loss of the anterolateral enrichment of actin normally seen in the oocyte.

(Leibfried et al., 2013)

Most of the zygotic mutant embryos for baz⁴ show normal dorsal closure.

Compared with wild-type embryos, baz⁴ mutants have significantly shorter duration time for actomyosin assembly-disassembly cycles.

baz⁴ mutant embryos show amnioserosa morphology defects.

(David et al., 2010)

The epithelia become disorganised in baz⁴ zygotic mutants after stages 11-13.

(Morais-de-Sá et al., 2010)

Dead embryos derived from a cross of heterozygous females to wild-type males have cuticles which are largely intact with one or two small holes often at the head.

(Shao et al., 2010)

Stage 11 embryos lacking both maternal and zygotic baz⁴ exhibit lost or severely disrupted tubule cell polarity.

(Campbell et al., 2009)

At early and mid cellularization, baz⁴ mutants exhibit apical surface puncta and basal junctions. At late cellularization, apical surface puncta persist abnormally compared to wild-type controls. baz⁴ mutants continue to have apical surface puncta as gastrulations begins, along with abnormal cell shapes.

(McGill et al., 2009)

baz⁴ mutant embryos display disorganised nervous systems, but the nervous system is not hyper-neuralised.

(Bayraktar et al., 2006)

baz⁴/Y zygotic mutants die as embryos, typically with one hole in the embryonic cuticle, due to epithelial polarity defects.

(Harris and Peifer, 2005)

Embryos maternally and zygotically mutant for baz⁴ fail to redistribute and assemble the shg gene product into spot junctions.

(Harris and Peifer, 2004)

Somatic clones homozygous for baz⁴ in the ovarian follicle cells cause discontinuities and multilayering of the epithelium. When the majority of border cells are part of a clone, the border cell cluster fails to migrate. However, clusters with a minority of mutant cells migrate normally. The morphology of mutant clusters is frequently abnormal - clusters are often elongated, sometimes with cells trailing behind the migrating cluster.

Border cell migration is incomplete in 14% of stage 10 egg chambers from (baz^{dsRNA.Sym.Scer\UAS})X2; Scer\GAL4^slbo.2.6 flies. This increases to 33% in flies also heterozygous for baz⁴.

(Pinheiro and Montell, 2004)

heterozygotes have a decreased number of synaptic boutons at neuromuscular junctions.

(Ruiz-Canada et al., 2004)

neuroblast divisions that produce equal-sized daughter cells are not seen in baz⁴ mutant embryos. In telophase pI cells in the majority of baz⁴ somatic clones (6/9) the distance from cleavage furrow to the anterior centrosome is greater than that to the posterior centrosome, but it is not clear whether spindle displacement is affected.

(Cai et al., 2003)

Marker analysis suggests that apical-basal polarity is disrupted in the pupal eye disc photoreceptor cells that are part of baz⁴ mutant clones. In addition. the shape and polarity of wild-type photoreceptors in mosaic ommatidia is often disrupted, although not as severely as in mutant cells. Photoreceptor differentiation, numbers and pattern are all normal in these clones at early pupal stages. However, baz⁴ mutant clones do not survive in the developing eye at late pupal stages, and the resulting adults eyes have many malformed ommatidia containing fewer than 7 photoreceptors.

(Hong et al., 2003)

Homozygous embryos have holes in the cuticle.

(Tanentzapf and Tepass, 2003)

The blastoderm epithelium is multilayered and the cells show a very irregular shape at gastrulation in mutant embryos derived from homozygous female germline clones. In hemizygous embryos derived from homozygous female germline clones abnormal orientation of metaphase plates with respect to the surface of the embryo is seen. In heterozygous embryos derived from homozygous female germline clones the neuroectodermal epithelium almost completely disintegrates. Many mutant embryos derived from homozygous female germline clones do not produce cuticle. Zygotic baz⁴ mutant embryos form cuticles with large ventral holes and head defects.

(Wodarz et al., 2000)

Homozygous embryos derived from homozygous female germline clones (lacking both maternal and zygotic baz function) show a fully penetrant spindle orientation defect in neuroblasts. The position of the budding ganglion mother cell with respect to the apical-basal axis of the neuroblast is random.

(Wodarz et al., 1999)

Homozygous embryos derived from germ line clones exhibit severe malformations or an absence of epidermis. They also exhibit abnormal zonula adherens formation and mislocalisation of membrane protein neurotactin.

(Muller and Wieschaus, 1996)

baz⁴ mutant embryos have large dorsal and ventral holes.

(Tearle and Nusslein-Volhard, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

baz⁴ has lethal | embryonic stage phenotype, enhanceable by Dhc64C^6-6/Dhc64C^6-8

(Harris and Peifer, 2005)

baz⁴ has abnormal cell polarity phenotype, enhanceable by Dhc64C^6-6/Dhc64C^6-8

(Harris and Peifer, 2005)

NOT Enhanced by

Statement

Reference

baz⁴ has abnormal neuroanatomy phenotype, non-enhanceable by aPKC^Exc55

(Ruiz-Canada et al., 2004)

NOT suppressed by

Statement

Reference

baz⁴ has abnormal neuroanatomy phenotype, non-suppressible by aPKC^Exc55

(Ruiz-Canada et al., 2004)

Enhancer of

Statement

Reference

baz⁴/baz[+] is an enhancer of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

baz⁴/baz[+] is an enhancer of visible | dominant phenotype of Fmr1^sev.PW

(Zarnescu et al., 2005)

baz⁴/baz⁴ is an enhancer | somatic clone of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI/Scer\GAL4^Act5C.PI

(Pagliarini and Xu, 2003)

Suppressor of

Statement

Reference

baz⁴ is a suppressor of visible phenotype of H^Scer\UAS.cMa/H^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Müller et al., 2005)

NOT Suppressor of

Statement

Reference

baz⁴/baz[+] is a non-suppressor of abnormal neuroanatomy phenotype of aPKC^Exc55

(Ruiz-Canada et al., 2004)

Other

Statement

Reference

baz⁴/baz[+], wts^x1 has abnormal neuroanatomy | embryonic stage phenotype

(Keder et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

baz⁴ has embryonic/first instar larval cuticle phenotype, enhanceable by zip[+]/zip¹

(David et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by crb^11A22/crb[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by shg[+]/shg^R69

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by aPKC^k06403/aPKC[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by ed[+]/ed^kg

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2L)Exel6039/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2L)ED1473/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2L)Exel7027/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2L)Exel6012/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)Exel7121/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)Exel7144/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)ED3943/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)ED1742/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)ED3728/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)ED1791/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(2R)ED3610/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by +/Df(3L)ED4287

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3L)ED5017/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by +/Df(3L)ED201

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by +/Df(3L)ED225

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)Exel6204/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by +/Df(3R)ED5559

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)Exel6211/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)ED5623/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)ED6220/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)Exel6196/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)ED5429/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Df(3R)ED6187/+

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by fj^d1/fj[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by par-1^W3/par-1[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by muskelin^f04338/muskelin[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Septin5^f04717/Sep5[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by alt[+]/alt^KG08013

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Rho1^72O/Rho1[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by asp¹/asp[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Arf79F[+]/Arf79F^C005

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by hk[+]/hook¹

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Asap1[+]/Asap^KG03963

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by CG1951^EY00129/CG1951[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by sds22^e00975/sds22[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Cul5^EY00051/Cul-5[+]

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by Roc2[+]/Roc2^EP2487

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by CG5823[+]/CG5823^f04935

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by CG10702[+]/CG10702^f03893

(Shao et al., 2010)

baz⁴ has embryonic/larval cuticle phenotype, enhanceable by CG11210[+]/Tmem63^KG08546

(Shao et al., 2010)

baz⁴ has embryonic/first instar larval cuticle phenotype, enhanceable by Dhc64C^6-6/Dhc64C^6-8

(Harris and Peifer, 2005)

NOT Enhanced by

Statement

Reference

baz⁴ has bouton phenotype, non-enhanceable by aPKC^Exc55

(Ruiz-Canada et al., 2004)

NOT suppressed by

Statement

Reference

baz⁴ has bouton phenotype, non-suppressible by aPKC^Exc55

(Ruiz-Canada et al., 2004)

Enhancer of

Statement

Reference

baz⁴/baz[+] is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

baz⁴/baz[+] is an enhancer of oocyte nucleus | oogenesis stage S9 phenotype of sktl^Δ15/sktl^2.3

(Gervais et al., 2008)

baz⁴/baz[+] is an enhancer of oocyte nucleus | oogenesis stage S10 phenotype of sktl^Δ15/sktl^2.3

(Gervais et al., 2008)

baz⁴/baz[+] is an enhancer of ommatidium phenotype of Fmr1^sev.PW

(Zarnescu et al., 2005)

NOT Enhancer of

Statement

Reference

baz⁴/baz[+] is a non-enhancer of wing hair phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

baz⁴/baz[+] is a non-enhancer of ommatidium phenotype of Vang^stbm-153

(Courbard et al., 2009)

baz⁴/baz[+] is a non-enhancer of bouton phenotype of aPKC^Exc55

(Ruiz-Canada et al., 2004)

Suppressor of

Statement

Reference

baz⁴ is a suppressor of eye phenotype of H^Scer\UAS.cMa/H^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Müller et al., 2005)

NOT Suppressor of

Statement

Reference

baz⁴/baz[+] is a non-suppressor of wing hair phenotype of Scer\GAL4^hs.2sev, dgo^UAS.cFa

(Weber et al., 2012)

baz⁴/baz[+] is a non-suppressor of ommatidium phenotype of Vang^stbm-153

(Courbard et al., 2009)

Other

Statement

Reference

baz⁴/baz[+], wts^x1 has RP2 motor neuron | embryonic stage phenotype

(Keder et al., 2015)

baz⁴, sdt^XN/sdt^XN has embryonic/first instar larval cuticle phenotype

(Tanentzapf and Tepass, 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Cells in baz⁴ homozygous clones in a homozygous Magi^bst wing disc are viable and show no loss of polarity.

(Padash Barmchi et al., 2016)

The proportion of hemisegments with abnormal number of neurons in the asymmetrically dividing RP2 neural lineage is significantly increased in wts^x1/+;baz⁴/+ double heterozygous embryos compared to either of the single heterozygotes or wild type.

(Keder et al., 2015)

baz⁴/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgo^Scer\UAS.cFa under the control of Scer\GAL4^hs.2sev.

(Weber et al., 2012)

zip¹/+ enhances the baz⁴ embryonic phenotype, generating merged dorsal head holes and ventral holes.

(David et al., 2010)

The cuticle phenotype of dead embryos derived from baz⁴/+ embryos derived from a cross of baz⁴/+ females to wild-type males is enhanced if the females also carry one copy of crb^11A22, shg^R69, aPKC^k06403, ed^kg, Df(2L)Exel6039, Df(2L)ED1473, Df(2L)Exel7027, Df(2L)Exel6012, Df(2R)Exel7121, Df(2R)Exel7144, Df(2R)ED3943, Df(2R)ED1742, Df(2R)ED3728, Df(2R)ED1791, Df(2R)ED3610, Df(3L)ED4287, Df(3L)ED5017, Df(3L)ED201, Df(3L)ED225, Df(3R)Exel6204, Df(3R)ED5559, Df(3R)Exel6211, Df(3R)ED5623, Df(3R)ED6220, Df(3R)Exel6196, Df(3R)ED5429 or Df(3R)ED6187.

The cuticle phenotype of dead embryos derived from baz⁴/+ embryos derived from a cross of baz⁴/+ females to wild-type males is enhanced if the females also carry one copy of fj^d1, par-1^W3, muskelin^f04338, Sep5^f04717, alt^KG08013, Rho1^72O, asp¹, Arf79F^C005, hk¹, Asap1^KG03963, CG1951^EY00129, sds22^e00975, Cul-5^EY00051, Roc2^EP2487, CG5823^f04935, CG10702^f03893 or CG11210^KG08546.

(Shao et al., 2010)

Heterozygosity for baz⁴ has no effect on the frequency of ommatidia that show planar cell polarity defects in Vang^stbm-153 homozygotes.

(Courbard et al., 2009)

baz⁴/+ enhances the nucleus mislocalisation defect seen in stage 9-10 sktl^2.3/sktl^Δ15 oocytes, such that 63% have a mislocalised nucleus.

(Gervais et al., 2008)

The baz⁴/+ phenotype is enhanced in homozygous, heterozygous or trans-heterozygous Dhc64C^6-6 or Dhc64C^6-8 mutants, resulting in larger cuticle holes and an overall loss of cuticle.

(Harris and Peifer, 2005)

baz⁴ sdt^XP follicle cell clones expressing baz^{S151A.S1085A.Scer\UAS.P\T.T:Avic\GFP} under the control of Scer\GAL4^e22c lose their epithelial organisation and form multilayers of cells.

(Benton and St. Johnston, 2003)

dlg1¹⁴ baz⁴ embryos (which lack both maternal and zygotic dlg1 and baz function) have cuticle phenotypes which are indistinguishable from baz⁴ embryos lacking maternal and zygotic baz function; the embryos show a severe loss of post-gastrulation adherens junctions and fail to produce cuticle.

(Bilder et al., 2003)

Marked clones in the eye disc expressing Ras85D^V12.Scer\UAS under the control of Scer\GAL4^Act5C.PI and which are also homozygous for baz⁴ show metastatic behaviour.

(Pagliarini and Xu, 2003)

Most sdt^XN baz⁴ double mutant embryos do not secrete any cuticle, while some embryos have a small number of cuticle grains that appear solid, rather than vesicular. The amount of cuticle produced in sdt^XN baz⁴ mutant embryos is not significantly increased if they also carry Df(3L)H99.

(Tanentzapf and Tepass, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

baz⁴ is rescued by baz^C.UASp.EGFP/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is rescued by baz^{ΔPDZ1.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is rescued by baz^{ΔPDZ3.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is rescued by baz^UASp.GFP/Scer\GAL4^Act5C.PI/Scer\GAL4^Act5C.PI

(Morais-de-Sá et al., 2010)

baz⁴ is rescued by baz^UASp.GFP/Scer\GAL4^{VP16.mat.αTub67C}

(Morais-de-Sá et al., 2010)

baz⁴ is rescued by baz^{S980E.UASp.mGFP6}/Scer\GAL4^Act5C.PI/Scer\GAL4^Act5C.PI

(Morais-de-Sá et al., 2010)

baz⁴ is rescued by baz^{S980E.UASp.mGFP6}/Scer\GAL4^{VP16.mat.αTub67C}

(Morais-de-Sá et al., 2010)

Partially rescued by

baz⁴ is partially rescued by baz^{ΔPDZ2.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is partially rescued by baz^{ΔPDZ1-2.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is partially rescued by baz^{ΔPDZ1+3.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is partially rescued by baz^{ΔPDZ2-3.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

baz⁴ is partially rescued by baz^{ΔPDZ1-3.UASp.EGFP}/Scer\GAL4^{VP16.mat.αTub67C}

(McKinley et al., 2012)

Not rescued by

baz⁴ is not rescued by baz^{S980A.UASp.mGFP6}/Scer\GAL4^{VP16.mat.αTub67C}

(Morais-de-Sá et al., 2010)

Comments

Expression of baz^{Scer\UAS.P\T.T:Avic\GFP} or baz^{S980E.Scer\UAS.P\T.T:Avic\GFP-m6} under the control of Scer\GAL4^Act5C.PI in clones in the follicular epithelium rescues the epithelial organisation defects seen in the follicle cells of baz⁴ females.

The epithelial organisation defects seen in baz⁴ zygotic mutant embryos are rescued by zygotic expression of baz^{Scer\UAS.P\T.T:Avic\GFP} or baz^{S980E.Scer\UAS.P\T.T:Avic\GFP-m6} under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16}.

The epithelial organisation defects seen in baz⁴ zygotic mutant embryos are not rescued by zygotic expression of baz^{S980A.Scer\UAS.P\T.T:Avic\GFP-m6} under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16}.

(Morais-de-Sá et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

3295

y¹ baz⁴/FM7a

23229

y¹ w^* baz⁴ P{FRT(w^hs)}9-2/FM7c, P{Dfd-GMR-nvYFP}1, sn⁺

Kyoto

106963

y¹ baz⁴/FM7c

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

baz-4

(Atwood et al., 2007)

baz⁴

(Liu et al., 2020, Chen et al., 2018, O'Neill and Clark, 2016, Padash Barmchi et al., 2016, Keder et al., 2015, Weber et al., 2012, Goossens et al., 2011, Spindler and Hartenstein, 2011, Becalska and Gavis, 2010, Doerflinger et al., 2010, Morais-de-Sá et al., 2010, Courbard et al., 2009, Gervais et al., 2008, Sotillos et al., 2008, Djiane et al., 2005, Zarnescu et al., 2005)

baz^XI106

(de Vreede et al., 2014, Bayraktar et al., 2006, Bilder et al., 2003)

baz^XI

(Zaessinger et al., 2015, Tearle and Nusslein-Volhard, 1987)

baz^XJ106

(David et al., 2005, Bellaiche et al., 2004)

baz^Xi

(Hong et al., 2003, Tanentzapf and Tepass, 2003)

baz^xi106

(Nunes de Almeida et al., 2019, Jauffred et al., 2013, Leibfried et al., 2013, Campbell et al., 2009, Pinal et al., 2006, Wei et al., 2005, Pinheiro and Montell, 2004, Roegiers et al., 2001)

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