Hemizygous males show fusion of veins at the base of the wing and a small amount of notching at the wing tip.
biomb-1/Y flies show a small notching of the wing tip in less than 10% of cases. A cluster of dying cells appears in the primordial wing tip in the late third larval instar biomb-1/Y wing disc.
Disruption of visual input can unmask CaMKII-dependent memory formation. Locomotor activity shows no defects in white or dim red light.
Proximal fusion of all longitudinal veins and variable defects at the tip of the wing. These defects become more severe over null mutations and are dominantly enhanced by mutations in ap and dpp. Impaired in the large field optomotor response in flight and walking.
Reduction in fibre number in the anterior optic tracts.
Normal external morphology but with discrete defects in optic lobes and behaviour. Reduction in wing size and increase in tergite pigmentation.
Flies have an increased reflectance on the wing surface, indicative of the lac phenotype. The lac phenotype is caused by position effect or second site mutation rather than directly at the breakpoint.
ERG defect, slow return of the potential to base light at light off.
The optomotor yaw response is reduced to 12% of the wild-type response. The lobula plate is reduced in thickness. The giant VS- and HS-cells are present but are reduced in size. The distribution of metabolic activity (measured by 3H-deoxyglucose autoradiography) in the optic lobes does not differ substantially from wild-type.
Mushroom bodies have normal size and shape. Normal olfactory learning. Structural defects are restricted to visual system.
Defects in the lobula plate giant neurones of the visual system.
Adults impaired in optomotor turning responses in tests involving tethered or freely moving flies (FBrf0032046; FBrf0038345; FBrf0048204; FBrf0050160). The mutant is also aberrant in orientation to vertical stripe (FBrf0032046). More detailed examination of 'yaw torque' optomotor responses show that mutant is restricted in responses to stimulation of 'frontal visual field', with mutant behavior summarized as retaining 'object responses' but missing 'large field responses' (FBrf0044893). The mutant is relatively normal in 'lift/thrust' response to vertical pattern movement and in regard to landing response elicited by front-to-back horizontal motion. Slow phototaxis, using Y-tube, was markedly subnormal (FBrf0050160). Mutants show anomalous avoidance reaction, i.e., 'antifixation' to objects in Y-maze test (FBrf0063339); courting males exhibit diminished tracking responses of and turning responses to moving females (FBrf0034187; FBrf0037487). Visual stimulus-induced metabolic activity in the optic lobes