FB2025_01 , released February 20, 2025
Allele: Dmel\br4
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General Information
Symbol
Dmel\br4
Species
D. melanogaster
Name
FlyBase ID
FBal0001191
Feature type
allele
Associated gene
Dmel\br
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
DNA
Progenitor genotype
Caused by aberration
T(1;2)br4
Cytology
Description

inserts at 109 and 115 kb + small deletion between 102 and 104 kb

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Affects female fertility.

      (Mazina et al., 1991)

      Heterozygotes with Dp(1;Y)y267g19.1 are lethal.

      (Belyaeva et al., 1982)

      Extreme expression of bruq phenotype. br4/br1 and br4/bruq have mutant phenotype. RK1.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Fahmy, 1954.

      Mutagen comment: DNA administered by feeding.

      Comments
      Comments

      Homozygous lethality is probably caused by another, second site, lethal mutation.

      (Belyaeva et al., 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      br4
      br59j
      Name Synonyms
      Secondary FlyBase IDs
        References (9)