Allele Dmel\bur¹

General Information
Symbol	Dmel\bur¹	Species	D. melanogaster
Name		FlyBase ID	FBal0001338
Feature type	allele	Associated gene	Dmel\bur

Allele class
Mutagen	U.V.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	U.V. (Meyer and Edmondson, 1949)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	eye color defective eye color defective \| recessive (Meyer and Edmondson, 1949) female fertile (Meyer and Edmondson, 1949) female fertile \| good male fertile \| partially (Meyer and Edmondson, 1949) viable (van der Knaap et al., 2005, Meyer and Edmondson, 1949) visible \| recessive
Phenotype Manifest In
	pigment cell (Meyer and Edmondson, 1949)
Detailed Description
	Statement Reference RK1. Eye colour: dull darkish brown, like pr. Fertility is good in females, but variable in males. (Meyer and Edmondson, 1949) Eye colour: dull, darkish brown (like pr). Eye colour: brilliant orange, with cn¹. RK1.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference bur¹/bur[+] is an enhancer of visible \| homeotic phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of visible \| recessive \| homeotic phenotype of Pc³ (van der Knaap et al., 2005)
Other
Statement Reference bur¹, cn^unspecified has eye color defective phenotype (Meyer and Edmondson, 1949, Meyer and Edmondson, 1949)
Phenotype Manifest In
Enhancer of
Statement Reference bur¹/bur[+] is an enhancer of abdominal segment 4 \| male phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of abdominal segment 5 \| ectopic \| male phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of haltere \| ectopic \| female phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of haltere \| ectopic phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of prothoracic leg \| ectopic \| male phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of prothoracic leg \| ectopic \| male phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of sex comb \| ectopic \| male phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of sex comb \| ectopic \| male phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of wing \| female phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is an enhancer of wing phenotype of Pc¹ (van der Knaap et al., 2005)
Suppressor of
Statement Reference bur¹/bur[+] is a suppressor of abdominal segment 4 \| male phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is a suppressor of abdominal segment 5 \| ectopic \| male phenotype of Pc³ (van der Knaap et al., 2005) bur¹/bur[+] is a suppressor of mesothoracic leg phenotype of Pc¹ (van der Knaap et al., 2005) bur¹/bur[+] is a suppressor of mesothoracic leg phenotype of Pc³ (van der Knaap et al., 2005)
Other
Statement Reference Pc³, bur¹/bur[+] has antenna \| female phenotype (van der Knaap et al., 2005) Pc³, bur¹/bur[+] has haltere \| ectopic \| male phenotype (van der Knaap et al., 2005) Pc³, bur¹/bur[+] has leg \| ectopic \| female phenotype (van der Knaap et al., 2005) Pc³, bur¹/bur[+] has wing \| male phenotype (van der Knaap et al., 2005) Pc³, bur¹ has antenna \| female phenotype (van der Knaap et al., 2005) Pc³, bur¹ has haltere \| ectopic \| male phenotype (van der Knaap et al., 2005) Pc³, bur¹ has leg \| ectopic \| female phenotype (van der Knaap et al., 2005) Pc³, bur¹ has wing \| male phenotype (van der Knaap et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference Flies transheterozygous for bur¹ and Pc¹ or Pc³ exhibit a 2-fold increase in the frequency of L2-L1 transformations, compared to heterozygous Pc¹ or Pc³ mutations. (van der Knaap et al., 2005) Produces a brilliant orange eye colour in combination with cn^unspecified. (Meyer and Edmondson, 1949)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 5 )
Bloomington	1548 bur¹ cn¹ 244 bur¹ fs(2)E1¹/SM5
Kyoto	106378 bur¹ cn¹ 105811 bur¹ fs(2)E1¹/SM5 101338 bur¹ fs(2)E1¹ / SM5, al² Cy¹ lt^v cn² sp²
Notes on Origin
Discoverer

Comments
	Classification excellent.
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	bur (Meyer and Edmondson, 1949) bur¹ (Long et al., 2006) Gmps¹ (van der Knaap et al., 2005)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Long et al., 2006, Genetics 172(3): 1633--1642 De novo GMP synthesis is required for axon guidance in Drosophila. [FBrf0190740] van der Knaap et al., 2005, Mol. Cell 17(5): 695--707 GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. [FBrf0184151] Meyer and Edmondson, 1949, D. I. S. 23: 60--61 [New mutants report.] [FBrf0063681]
Book	Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Allele Dmel\bur1

Allele Dmel\bur¹