Allele Dmel\csw⁷

General Information
Symbol	Dmel\csw⁷	Species	D. melanogaster
Name		FlyBase ID	FBal0001926
Feature type	allele	Associated gene	Dmel\csw
Also Known As	csw^19-106

Allele class	hypomorphic allele - genetic evidence
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Perkins et al., 1992)
Mutagen	spontaneous (Kramers et al., 1983, Schalet, 1986, Perkins et al., 1992, Perkins et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage \| germline clone \| rescuable maternal effect (Perkins et al., 1996) lethal \| pupal stage (Perkins et al., 1992) lethal \| pupal stage \| recessive (Perkins et al., 1996) lethal \| recessive (Kramers et al., 1983, Schalet, 1986)
Phenotype Manifest In
	embryonic/first instar larval cuticle \| germline clone (Perkins et al., 1996)
Detailed Description
	Statement Reference csw⁷ germline clone mosaics cause maternal effect lethality. Embryos derived from mothers with germline clones that exhibit a corkscrew cuticle phenotype (8%) have slight paternal rescue of the germline clone phenotype, embryos that do not receive a wild type copy from their father (92%), null embryos, die with a 'U'-shaped cuticle phenotype. (Perkins et al., 1996) Abnormal development of terminal internal structures. (Perkins et al., 1992)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Schalet. Schalet.

Comments
	Phenotypic series of csw mutant embryos derived from homozygous germline clones, classified according to cuticular phenotype: csw⁵ = csw^LE120 > csw¹ = csw^13-87 > csw^e13d.3 > csw⁷ = csw⁶. (Perkins et al., 1996)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	19-106 (Kramers et al., 1983) csw⁷ csw^19-106 (Ghiglione et al., 1999, Perkins et al., 1996, Perkins et al., 1992) l(1)19-106 (Schalet, 1986, )
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Ghiglione et al., 1999, Dev. Biol. 205(1): 181--193 Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila. [FBrf0105831] Perkins et al., 1996, Dev. Biol. 180(1): 63--81 The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. [FBrf0090739] Perkins et al., 1992, Cell 70: 225--236 corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. [FBrf0055550] Schalet, 1986, Mutat. Res. 163: 115--144 The distribution of and complementation relationships between spontaneous X-linked recessive lethal mutations recovered from crossing long-term laboratory stocks of Drosophila melanogaster. [FBrf0045066] Kramers et al., 1983, Mutat. Res. 107: 187--201 High proportion of multi-locus deletions among hycanthone-induced X-linked recessive lethals in Drosophila melanogaster. [FBrf0039985]

Allele Dmel\csw7

Allele Dmel\csw⁷