FlyBase Allele Report: Dmel\ct[53d]

General Information

Symbol

Dmel\ct^53d

Species

D. melanogaster

Name

FlyBase ID

FBal0001938

Feature type

allele

Associated gene

Dmel\ct

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

0.5kb deletion of sequences within the wing margin enhancer.

(Morcillo et al., 1996)

0.5kb deletion that probably partially deletes the ct wing enhancer.

(Jack and DeLotto, 1992)

Small 0.5kb deletion 80kb upstream from the first exon.

(Jack et al., 1991)

DNA coordinates (FBrf0042060) (0 is gypsy site in ct⁶): 0.5 kb deletion in -6.8 to -4.8

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Krupp et al., 2005, Thumm and Kadowaki, 2001, Rollins et al., 1999)

visible | recessive

(Morcillo et al., 1996, Jack and DeLotto, 1992)

Phenotype Manifest In

wing

(Thumm and Kadowaki, 2001, Helms et al., 1999, Rollins et al., 1999, Morcillo et al., 1996, Jack and DeLotto, 1992)

wing margin

(Krupp et al., 2005, Eissenberg et al., 2002)

Detailed Description

Statement

Reference

ct^53d mutants have notched wings.

(Eissenberg et al., 2002)

ct^53d adults have a weak wing notching phenotype.

(Thumm and Kadowaki, 2001)

ct^53d/Y flies show a minor wing nicking phenotype.

(Helms et al., 1999)

Hemizygous males show about 7 nicks per fly in an otherwise wild type background.

(Rollins et al., 1999)

Partial cut wing phenotype.

(Morcillo et al., 1996)

Homozygous ct^53d flies are missing tissue from the wing tip and the posterior margin.

(Jack and DeLotto, 1992)

Adult wing margin has gaps at the tip.

(Jack et al., 1991)

cut wings

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

ct^53d has visible phenotype, enhanceable by +/Df(2R)ED1552

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by +/Df(3L)brm11

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by +/Df(3R)slo8

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by brm[+]/brm²

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA}

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by mor[+]/mor¹

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by Scer\GAL4^bbg-C96/mor^GS-A897

(Krupp et al., 2005)

ct^53d has visible phenotype, enhanceable by Scer\GAL4^bbg-C96/osa^VP16.AD.UAS

(Krupp et al., 2005)

NOT Enhanced by

Statement

Reference

ct^53d has visible phenotype, non-enhanceable by Df(1)N12/+

(Krupp et al., 2005)

ct^53d has visible phenotype, non-enhanceable by +/Df(2R)Exel7147

(Krupp et al., 2005)

ct^53d has visible phenotype, non-enhanceable by Df(3R)Exel7327/+

(Krupp et al., 2005)

ct^53d has visible phenotype, non-enhanceable by Snr1⁰¹³¹⁹/Snr1[+]

(Krupp et al., 2005)

ct^53d has visible phenotype, non-enhanceable by osa²/osa[+]

(Krupp et al., 2005)

Suppressed by

Statement

Reference

ct^53d has visible phenotype, suppressible by Scer\GAL4^bbg-C96/osa^RD.UAS

(Krupp et al., 2005)

ct^53d has visible phenotype, suppressible by osa^UAS.cCa/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

NOT suppressed by

Statement

Reference

ct^53d has visible phenotype, non-suppressible by Df(1)N12/+

(Krupp et al., 2005)

ct^53d has visible phenotype, non-suppressible by +/Df(2R)Exel7147

(Krupp et al., 2005)

ct^53d has visible phenotype, non-suppressible by Df(3R)Exel7327/+

(Krupp et al., 2005)

ct^53d has visible phenotype, non-suppressible by Snr1⁰¹³¹⁹/Snr1[+]

(Krupp et al., 2005)

ct^53d has visible phenotype, non-suppressible by osa²/osa[+]

(Krupp et al., 2005)

Enhancer of

Statement

Reference

ct^53d is an enhancer of visible phenotype of Scer\GAL4^bbg-C96, mam^N.UAS

(Helms et al., 1999)

Other

Statement

Reference

ct^53d, mam^g2.1/mam[+] has visible phenotype

(Morcillo et al., 1996)

Phenotype Manifest In

Enhanced by

Statement

Reference

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/Aef1^GS-A2724

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/Sph35^GS-A2688

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/Psc^GS-A2026

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/SMSr^GS-A2330

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by chic^GS-A2665/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by eIF4E1^GS-A2783/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/eIF4A^GS-A2207

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/fus^GS-A1497

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by lwr^GS-A2612/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/sqz^GS-A2967

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by +/Df(2R)ED1552

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by +/Df(3L)brm11

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by +/Df(3R)slo8

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by brm[+]/brm²

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA}

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by mor[+]/mor¹

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by Scer\GAL4^bbg-C96/mor^GS-A897

(Krupp et al., 2005)

ct^53d has wing phenotype, enhanceable by Scer\GAL4^bbg-C96/osa^VP16.AD.UAS

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by lola^5D2/lola[+]

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by lola^KG09113/lola[+]

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by lola[+]/lola^ORE119

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by lola^ORE120/lola[+]

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by lola^e76/lola[+]

(Krupp et al., 2005)

ct^53d has phenotype, enhanceable by Scer\GAL4^bbg-C96/wde^GS-A2450

(Krupp et al., 2005)

ct^53d has wing margin phenotype, enhanceable by Su(Tpl)[+]/Su(Tpl)¹⁰

(Eissenberg et al., 2002)

ct^53d has wing margin phenotype, enhanceable by Su(Tpl)[+]/Su(Tpl)¹⁷

(Eissenberg et al., 2002)

ct^53d has wing margin phenotype, enhanceable by Su(Tpl)[+]/Su(Tpl)^S-192

(Eissenberg et al., 2002)

ct^53d has wing margin phenotype, enhanceable by Su(Tpl)^XS-706/Su(Tpl)[+]

(Eissenberg et al., 2002)

ct^53d has wing margin phenotype, enhanceable by Su(Tpl)[+]/Su(Tpl)^s1

(Eissenberg et al., 2002)

ct^53d has wing phenotype, enhanceable by Atg4b^P0997

(Thumm and Kadowaki, 2001)

ct^53d has wing phenotype, enhanceable by Nipped-A³²³

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Nipped-A^394.2

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by RpL38^45-72

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by T(2;3)Nipped-C138.2

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)Nipped-D341.1

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)Nipped-D263.3

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)Nipped-E299.1

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)Nipped-E43

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)Nipped-E338

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Df(2R)M41A8

(Rollins et al., 1999)

ct^53d has wing phenotype, enhanceable by Nipped-A^222.3

(Rollins et al., 1999)

ct^53d has phenotype, enhanceable by Chi^e5.5

(Morcillo et al., 1996)

ct^53d has phenotype, enhanceable by mam^g2.1

(Morcillo et al., 1996)

NOT Enhanced by

Statement

Reference

ct^53d has phenotype, non-enhanceable by psq^unspecified

(Krupp et al., 2005)

ct^53d has wing phenotype, non-enhanceable by Df(1)N12/+

(Krupp et al., 2005)

ct^53d has wing phenotype, non-enhanceable by +/Df(2R)Exel7147

(Krupp et al., 2005)

ct^53d has wing phenotype, non-enhanceable by Df(3R)Exel7327/+

(Krupp et al., 2005)

ct^53d has wing phenotype, non-enhanceable by Snr1⁰¹³¹⁹/Snr1[+]

(Krupp et al., 2005)

ct^53d has wing phenotype, non-enhanceable by osa²/osa[+]

(Krupp et al., 2005)

ct^53d has wing margin phenotype, non-enhanceable by lola[+]/lola^ORC4

(Krupp et al., 2005)

ct^53d has phenotype, non-enhanceable by Nipped-B^292.1

(Rollins et al., 1999)

ct^53d has phenotype, non-enhanceable by Nipped-B^359.1

(Rollins et al., 1999)

ct^53d has phenotype, non-enhanceable by Nipped-B⁴⁰⁷

(Rollins et al., 1999)

ct^53d has phenotype, non-enhanceable by Nipped-B⁴

(Rollins et al., 1999)

ct^53d has phenotype, non-enhanceable by Nipped-A²

(Rollins et al., 1999)

ct^53d has phenotype, non-enhanceable by Df(2R)Nipped-C160.1

(Rollins et al., 1999)

Suppressed by

Statement

Reference

ct^53d has phenotype, suppressible by CG14757^GS-A2066/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

ct^53d has phenotype, suppressible by Scer\GAL4^bbg-C96/CycE^GS-A1869

(Krupp et al., 2005)

ct^53d has phenotype, suppressible by Scer\GAL4^bbg-C96/brat^GS-A2233

(Krupp et al., 2005)

ct^53d has phenotype, suppressible by Scer\GAL4^bbg-C96/lola^GS-A916

(Krupp et al., 2005)

ct^53d has wing phenotype, suppressible by Scer\GAL4^bbg-C96/osa^RD.UAS

(Krupp et al., 2005)

ct^53d has wing phenotype, suppressible by osa^UAS.cCa/Scer\GAL4^bbg-C96

(Krupp et al., 2005)

NOT suppressed by

Statement

Reference

ct^53d has phenotype, non-suppressible by psq^unspecified

(Krupp et al., 2005)

ct^53d has wing phenotype, non-suppressible by osa²/osa[+]

(Krupp et al., 2005)

ct^53d has wing phenotype, non-suppressible by Df(1)N12/+

(Krupp et al., 2005)

ct^53d has wing phenotype, non-suppressible by +/Df(2R)Exel7147

(Krupp et al., 2005)

ct^53d has wing phenotype, non-suppressible by Df(3R)Exel7327/+

(Krupp et al., 2005)

ct^53d has wing phenotype, non-suppressible by Snr1⁰¹³¹⁹/Snr1[+]

(Krupp et al., 2005)

Enhancer of

Statement

Reference

ct^53d/ct[+] is an enhancer of wing margin phenotype of sno^71e3

(Majumdar et al., 1997)

Other

Statement

Reference

ct^53d, mam^g2.1/mam[+] has wing phenotype

(Morcillo et al., 1996)

ct^53d/ct[+], mam^g2.1 has wing phenotype

(Morcillo et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

Wing notching in ct^53d mutants is enhanced by heterozygosity for Su(Tpl)^s1, Su(Tpl)¹⁷, Su(Tpl)^XS-706, Su(Tpl)¹⁰, or Su(Tpl)^S-192.

(Eissenberg et al., 2002)

The wing notching phenotype seen in ct^53d adults is enhanced in a dose dependent manner by CG6194^P0997.

(Thumm and Kadowaki, 2001)

Enhances the wing nicking phenotype seen in mam^N.Scer\UAS, Scer\GAL4^C96 flies.

(Helms et al., 1999)

Nipped-B⁴⁰⁷ has little or no effect on this phenotype.

(Rollins et al., 1999)

mam^g2.1; ct^53d double heterozygotes display a visible cut wing phenotype.

(Morcillo et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Weak ct allele.

(Jack and DeLotto, 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ct^53d

(Rollins et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

Open Close