Allele Dmel\Cy¹

General Information
Symbol	Dmel\Cy¹	Species	D. melanogaster
Name		FlyBase ID	FBal0002196
Feature type	allele	Associated gene	Dmel\Cy
Also Known As	Cy

Allele class
Mutagen	spontaneous
Recent Updates
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FB2013_03
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Nature of the Allele
Allele class
Mutagen	spontaneous
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Carried on aberration	AM1 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) C(2R)RM-C5 CyO (FlyBase Curators, 2006-, Wright et al., 1976, Lindsley and Zimm, 1992) CyO-2XGMRrpr (FlyBase Curators, 2006-) CyO-7.1 (FlyBase Curators, 2006-) CyO-19 (FlyBase Curators, 2006-) CyO-23 (FlyBase Curators, 2006-) CyO-30 (FlyBase Curators, 2006-) CyO-37 (FlyBase Curators, 2006-) CyO-208 (FlyBase Curators, 2006-) CyO-217-038 (FlyBase Curators, 2006-) CyO-238-022 (FlyBase Curators, 2006-) CyO-238-048 (FlyBase Curators, 2006-) CyO-276 (FlyBase Curators, 2006-) CyO-402 (FlyBase Curators, 2006-) CyO-509 (FlyBase Curators, 2006-) CyO-520-009 (FlyBase Curators, 2006-) CyO-520-021 (FlyBase Curators, 2006-) CyO^T8LZ (FlyBase Curators, 2006-) CyO-A4 (FlyBase Curators, 2006-) CyO-A32 (FlyBase Curators, 2006-) CyO-A66 (FlyBase Curators, 2006-) CyO-A79 (FlyBase Curators, 2006-) CyO-A103 (FlyBase Curators, 2006-) CyO-A130 (FlyBase Curators, 2006-) CyO-A176 (FlyBase Curators, 2006-) CyO-A203 (FlyBase Curators, 2006-) CyO-A217 (FlyBase Curators, 2006-) CyO-A336 (FlyBase Curators, 2006-) CyO-A350 (FlyBase Curators, 2006-) CyO-A405 (FlyBase Curators, 2006-) CyO-A480 (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.9.24) CyO-A495 (FlyBase Curators, 2006-) CyO-A507 (FlyBase Curators, 2006-) CyO-B26.2-4.2 (FlyBase Curators, 2006-) CyO-B26.2-16.1 (FlyBase Curators, 2006-) CyO-B26.2-33.1 (FlyBase Curators, 2006-) CyO-B26.2-36.1 (FlyBase Curators, 2006-) CyO-B39 (FlyBase Curators, 2006-) CyO-b^81f1 (FlyBase Curators, 2006-) CyO-BG00000 (FlyBase Curators, 2006-) CyO-brk (FlyBase Curators, 2006-) CyO-bw (FlyBase Curators, 2006-) CyO-CC2 (FlyBase Curators, 2006-) CyO-CCAG (FlyBase Curators, 2006-) CyO-cl⁴ (FlyBase Curators, 2006-) CyO-cn⁺ (FlyBase Curators, 2006-, Mardahl et al., 1993) CyO-CR2 (FlyBase Curators, 2006-) CyO-CTG (FlyBase Curators, 2006-) CyO-CZ (FlyBase Curators, 2006-) CyO-Df(2L)noc20 (FlyBase Curators, 2006-) CyO-Df(2R)B80 (FlyBase Curators, 2006-) CyO-Df(2R)cn-S3 (FlyBase Curators, 2006-) CyO-Df(2R)cn-S6 (FlyBase Curators, 2006-) CyO-Dp(2;2)M(2)m⁺ (FlyBase Curators, 2006-) CyO-dpc (FlyBase Curators, 2006-) CyO-DTS100 (FlyBase Curators, 2006-) CyO-DTS486 (FlyBase Curators, 2006-) CyO-DTS513 (FlyBase Curators, 2006-) CyO-EY00000 (FlyBase Curators, 2006-) CyO-FRT (FlyBase Curators, 2006-) CyO-ftz-lacZ (FlyBase Curators, 2006-) CyO-G (FlyBase Curators, 2006-) CyO-GCY (FlyBase Curators, 2006-) CyO-GFP (FlyBase Curators, 2006-) CyO-GMRargos (FlyBase Curators, 2006-) CyO-GS046 (FlyBase Curators, 2006-) CyO-hb-β-gal (FlyBase Curators, 2006-) CyO-HoP2.1 (FlyBase Curators, 2006-) CyO-HoP3 (FlyBase Curators, 2006-) CyO-HShid (FlyBase Curators, 2006-) CyO-Hsp70-PBac\T.w⁺ (FlyBase Curators, 2006-) CyO-Hsp70-PBac\T.w^- (FlyBase Curators, 2006-) CyO-Mhc-lacZ (FlyBase Curators, 2006-) CyO-MiT2.4 (FlyBase Curators, 2006-) CyO-nec^JR (FlyBase Curators, 2006-) CyO-numb^k09918 (FlyBase Curators, 2006-) CyO-P20 (FlyBase Curators, 2006-) CyO-P{Crew} (FlyBase Curators, 2006-) CyO-P{dam⁺.phy705}11 (FlyBase Curators, 2006-) CyO-P{dam⁺.phy705}12 (FlyBase Curators, 2006-) CyO-P{dam⁺.phy705}34 (FlyBase Curators, 2006-) CyO-P{Dfd-EYFP.w^BmC}2 (FlyBase Curators, 2006-) CyO-P{Dfd-EYFP}2 (FlyBase Curators, 2006-) CyO-P{en1}wg^en11 (FlyBase Curators, 2006-) CyO-P{EPg}4-38 (FlyBase Curators, 2006-) CyO-P{ftz/lacC}USC1 (FlyBase Curators, 2006-) CyO-P{ftz-lacZ.w⁺} (FlyBase Curators, 2006-) CyO-P{GAL4-Hsp70.PB.w^mC.mut}MP (FlyBase Curators, 2006-) CyO-P{GMR-p21.Ex}2 (FlyBase Curators, 2006-) CyO-P{HBL1}1 (FlyBase Curators, 2006-) CyO-P{HBL1}2 (FlyBase Curators, 2006-) CyO-P{hsH\T-2}1 (FlyBase Curators, 2006-) CyO-P{hsH\T-2}2 (FlyBase Curators, 2006-) CyO-P{lacW}B (FlyBase Curators, 2006-) CyO-P{lacW}S (FlyBase Curators, 2006-) CyO-P{ovoD1-18}131 (FlyBase Curators, 2006-) CyO-P{sE-raf^torY9}475 (FlyBase Curators, 2006-) CyO-P{SUPor-P}RR1 (FlyBase Curators, 2006-) CyO-pAct-GFP (FlyBase Curators, 2006-, Reichhart and Ferrandon, 1998.6.8, Reichhart and Ferrandon, 1998) CyO-PBac{Delta2-3.Exel}2 (FlyBase Curators, 2006-) CyO-pcb (FlyBase Curators, 2006-) CyO-pk^pk-sple-46 (FlyBase Curators, 2006-) CyO-pk^pk-sple-47 (FlyBase Curators, 2006-) CyO-pk^pk-sple-48 (FlyBase Curators, 2006-) CyO-pk^pk-sple-49 (FlyBase Curators, 2006-) CyO-Rb (FlyBase Curators, 2006-) CyO-Rcb (FlyBase Curators, 2006-) CyO-Rcb(P) (FlyBase Curators, 2006-) CyO-Rs(P) (FlyBase Curators, 2006-) CyO-Sbw (FlyBase Curators, 2006-) CyO-SCY (FlyBase Curators, 2006-) CyO-sp (FlyBase Curators, 2006-) CyO-Thb8 (FlyBase Curators, 2006-) CyO-TM3-GFP (FlyBase Curators, 2006-) CyO-TM6B (FlyBase Curators, 2006-) CyO-TM9 (FlyBase Curators, 2006-) CyO-tub-Gal80 (FlyBase Curators, 2006-) CyO-Tub-PBac\T.w⁺ (FlyBase Curators, 2006-) CyO-Tub-PBac\T.w^- (FlyBase Curators, 2006-) CyO-UW14 (FlyBase Curators, 2006-) CyO-vAa (FlyBase Curators, 2006-) CyO-vAb (FlyBase Curators, 2006-) CyO-vAc (FlyBase Curators, 2006-) CyO-vAe (FlyBase Curators, 2006-) CyO-vAg (FlyBase Curators, 2006-) CyO-vDAa (FlyBase Curators, 2006-) CyO-vGa (FlyBase Curators, 2006-) CyO-vKa (FlyBase Curators, 2006-) CyO-vOa (FlyBase Curators, 2006-) CyO-vOb (FlyBase Curators, 2006-) CyO-vPa (FlyBase Curators, 2006-) CyO-vSa (FlyBase Curators, 2006-) CyO-vWa (FlyBase Curators, 2006-) CyO-vWb (FlyBase Curators, 2006-) CyO-y⁺ (FlyBase Curators, 2006-, Mardahl et al., 1993) CyO-Δ34B (FlyBase Curators, 2006-) CyO-Δ46G (FlyBase Curators, 2006-) CyO-β-actin (FlyBase Curators, 2006-) CyO-βE3 (FlyBase Curators, 2006-) In(2L)Cy (The Moscow Regional Drosophila melanogaster Stock Center, Dubna) SM1 (FlyBase Curators, 2006-, Wright et al., 1976, Lindsley and Zimm, 1992) SM1-amos^Roi-1 (FlyBase Curators, 2006-) SM1-dpBl (FlyBase Curators, 2006-) SM1-GMR-hid (FlyBase Curators, 2006-) SM1-Got2¹ (FlyBase Curators, 2006-) SM1-Hex-C⁴ (FlyBase Curators, 2006-) SM1-L⁴ (FlyBase Curators, 2006-) SM1-PP (FlyBase Curators, 2006-) SM1-vDa (FlyBase Curators, 2006-) SM1-vWa (FlyBase Curators, 2006-) SM2 (Lindsley and Zimm, 1992) SM5 (FlyBase Curators, 2006-, Wright et al., 1976, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) SM5-DTSL4 (FlyBase Curators, 2006-) SM6#16 (FlyBase Curators, 2006-) SM6a (FlyBase Curators, 2006-, Craymer, 1984, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) SM6a-bw^k1 (FlyBase Curators, 2006-) SM6a-P{RS3}CB-0100-3 (FlyBase Curators, 2006-) SM6a-P{RS3}CB-0102-3 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1005 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1006 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1007 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1018 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1023 (FlyBase Curators, 2006-) SM6a-P{RS5}5-HA-1026 (FlyBase Curators, 2006-) SM6a-TM6B (FlyBase Curators, 2006-) SM6b (FlyBase Curators, 2006-, Craymer, 1984, Lindsley and Zimm, 1992) SM6Bevelac (FlyBase Curators, 2006-) SM6b-P{70FLP}7 (FlyBase Curators, 2006-) T(2;3)S^M T(2;3)SM6b-TM6B (Kreber, 2004.7.20) TSTL (FlyBase Curators, 2006-) TSTL14 (FlyBase Curators, 2006-)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	wing (Zimm and Lindsley, 1996.1.25)
Detailed Description
	Statement Reference Cy¹ is dominant in D.melanogaster/D.simulans hybrids. (Goldschmidt, 1999) Wing phenotype is additive with that of U¹ and U². (Zimm and Lindsley, 1996.1.25) Wings curled upward; rarely overlaps wild type at 25^oC, but frequently overlaps at 19^oC. Curvature caused by the unequal contraction of the upper and lower epithelia during the drying period following emergence from the pupa case (Waddington, 1940). Flightless but thoracic innervation normal (Chiarodo, Reing and Saranchak, 1971). Expression decreased by larval crowding, increased by increased temperature during pupal development (Nozawa, 1956). Classifiable in single dose in triploids. Usually homozygous lethal but may emerge as dwarf with more extreme wing character. Effective lethal phase late embryo-early larva (Kidwell, 1972). Cy is readily revertable by both EMS and irradiation. In addition some balanced Cy chromosomes pick up suppressors of Cy in stock. RK1A.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference Cy¹ has phenotype, suppressible by Bl¹ (Meyer, 1952) Cy¹ has phenotype, suppressible by Su(Cy)¹ (Thompson, 1963)
NOT suppressed by
Statement Reference Cy¹ has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	Cy^67.3 (Stefancsik, 2002.5.22) Cy^K (Cook, 2008.12.1)
Comments	Complementation test based on lethal phenotype. (Stefancsik, 2002.5.22)
Stocks ( 362 )
Bloomington	880 T(2;3)Scar, Scar¹/Cy¹ 832 T(1;2)lt/In(2L)Cy, In(2R)Cy, Cy¹ 359 nw²/In(2L)Cy, In(2R)NS, Cy¹ 3548 Df(2L)al, ds^al/In(2L)Cy, Cy¹ 382 ade2¹⁰/In(2L)Cy, In(2R)Cy, Cy¹ 206 abr¹/In(2L)Cy, In(2R)Cy, Cy¹ hk²
Kyoto	101514 In(2L)Cy In(2R)NS, Cy¹ / nw² 106869 Df(2L)esc-P2-0/Cy¹ amos^Roi-1 106870 Df(2L)esc-P3-0/Cy¹ amos^Roi-1 107090 Df(2L)al, ds^al/In(2L)Cy, Cy¹ 105881 ade2¹⁰/In(2L)Cy, In(2R)Cy, Cy¹ 108965 T(2;3)A1-W, In(2L)Cy, In(2R)Cy, Cy¹ L¹
	More stocks available...
Notes on Origin
Discoverer

Comments
	The curly winged mutant phenotype can be suppressed by exposure to fluorescent light. (Pavelka et al., 1996)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Cy (Goldschmidt, 1999, Meyer, 1952) Cy¹ (Cook, 2008.12.1)
Name Synonym
Secondary FlyBase IDs

References ( 19 )
Research paper	Reichhart and Ferrandon, 1998, D. I. S. 81: 201--202 Green balancers. [FBrf0105466] Pavelka et al., 1996, Hereditas 124(2): 191--197 Suppression of the Drosophila Curly mutation by fluorescent light. [FBrf0089775] Mardahl et al., 1993, D. I. S. 72: 141 Introduction of y⁺ onto a CyO chromosome. [FBrf0057989] Craymer, 1984, D. I. S. 60: 234--236 [New mutants report.] [FBrf0063387] Wright et al., 1976, Genetics 84: 267--285 The genetics of dopa decarboxylase in Drosophila melanogaster. [FBrf0028752] Thompson, 1963, D. I. S. 38: 28 [New mutants report.] [FBrf0015196] Meyer, 1952, D. I. S. 26: 66--67 [New mutants report.] [FBrf0063684]
Personal communication to FlyBase	Cook, 2008.12.1, Mutations from Jim Kennison. Mutations from Jim Kennison. [FBrf0206482] Kreber, 2004.7.20, T(2;3)SM6b-TM6B. T(2;3)SM6b-TM6B. [FBrf0178900] Stefancsik, 2002.5.22, l(2)k05909. l(2)k05909. [FBrf0149625] Bloomington Drosophila Stock Center, 1998.5.16, balancer stuff. balancer stuff. [FBrf0102820] Bloomington Drosophila Stock Center, 1998.9.24, CyO and TM2 variants. CyO and TM2 variants. [FBrf0104934] Reichhart and Ferrandon, 1998.6.8, Green Balancers. Green Balancers. [FBrf0102825] Zimm and Lindsley, 1996.1.25, Upturned revisited with description of a new allele.. Upturned revisited with description of a new allele.. [FBrf0084573]
FlyBase analysis	FlyBase Curators, 2006-, Balancer summary information. Balancer summary information. [FBrf0189689]
Teaching note	Goldschmidt, 1999, D. I. S. 82: 129 Phenocopy and species hybrid in class work. [FBrf0111885]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905] Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]
Stock list	The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Russia, 1997, D. I. S. 80: 109--130 Stock list. [FBrf0098381]

Allele Dmel\Cy1

Allele Dmel\Cy¹