|Feature type||allele||Associated gene||Dmel\Dfd|
|Also Known As||DfdD|
|Map ( GBrowse )|
|Allele class||gain of function allele|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
50kb insertion within 1kb of the 3' end of the Dfd transcription unit that is flanked by multiple copies of roo elements. Also a duplication of the fourth and fifth Dfd exons on the distal side of the transposon flanked insertion.
Large transposon flanked insertion downstream of the Dfd transcription unit.
|Caused by insertion|
|Carried on aberration|
Polytene chromosomes normal.
|Phenotype Manifest In|
Heterozygous males have ectopic antero-ventral bristles on the head.
Adult head deformations: lower eye and orbital structures are absent. Homozygotes have bulbous growths in the place of missing eye tissue, these may be duplications of the second antennal segment.
Adults have ventral eye and orbital tissue missing.
Loss of ventral eye and orbital regions in the adult head. Head defects phenocopied by Dfdhs.PK constructs and heat-shock constructs of the human Hox4.2 in cells of the eye disc during third larval instar development.
Adult head defects.
dominant Eyes reduced ventrally and anteriorly, or furrowed. Vibrissae tufted. Extremely variable, often overlapping wild type, but usually excellent character with Ly or at 19oC. Classifiable in single dose in triploids (Schultz, 1934). Muller reported an occasional homozygote as extreme dwarf with flimsy wings. RK2.
|Phenotype Manifest In|
Hemizygous mxcM1 males have normal eyes. mxcM1/Y Dfd1/+ males have no aristae, and the maxillary palps and eyes are extremely reduced. mxcG46/Y Dfd1/+ and mxcG43/Y Dfd1/+ males have head defects.
|Complementation & Rescue Data|
|Stocks ( 18 )|
|Notes on Origin|
Cattell, July 1913.
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 4 )|
|Secondary FlyBase IDs|
|References ( 16 )|
|Personal communication to FlyBase|