FB2025_01 , released February 20, 2025
Allele: Dmel\Dfd6
Open Close
General Information
Symbol
Dmel\Dfd6
Species
D. melanogaster
Name
FlyBase ID
FBal0002379
Feature type
allele
Associated gene
Dmel\Dfd
Associated Insertion(s)
Carried in Construct
Also Known As
XaK2
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

Mutagen
X ray
(Lewis et al., 1980, Lewis et al., 1980)
Progenitor genotype
Cytology

?

Polytene chromosomes normal.

(Lewis et al., 1980)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Dfd[+]/Dfd6 is a suppressor | partially of lethal | pharate adult stage phenotype of Hsap\HTTQ138.UAS.mRFP1, Scer\GAL4elav-C155

      (Weiss et al., 2012)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      One copy of Dfd6 partially rescues the lethality seen when Hsap\HTTQ138.Scer\UAS.T:Disc\RFP-mRFP is expressed under the control of Scer\GAL4elav-C155 using the P{UAS-HTT.Q138.mRFP}A insertion line.

      (Weiss et al., 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Kaufman.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dfd6
      (Weiss et al., 2012)
      DfdrK2
      XaK2
      (Lewis et al., 1980, Lewis et al., 1980)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)