FlyBase Allele Report: Dmel\Delta[5F]

General Information

Symbol

Dmel\Delta^5F

Species

D. melanogaster

Name

FlyBase ID

FBal0002463

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

Also Known As

Dl^5F102, Dl^5F

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Tearle and Nusslein-Volhard, 1987)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | neurogenic phenotype | recessive

(Lehmann et al., 1983)

some die during embryonic stage | recessive

(Lehmann et al., 1983)

visible | adult stage

(Sachan et al., 2013)

Phenotype Manifest In

embryonic epidermis

(Lehmann et al., 1983)

wing vein

(Sachan et al., 2013)

Detailed Description

Statement

Reference

Dl^5F heterozygous adult flies display wing vein defects: vein deltas and vein thickening.

(Sachan et al., 2013)

Heterozygotes with Dl^vi1 display an enhancement of the embryonic phenotype.

(Vassin and Campos-Ortega, 1987)

Extreme embryonic neurogenic phenotype.

(Lehmann et al., 1983)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta^5F has visible | adult stage phenotype, enhanceable by Kap-α3^S033513

(Sachan et al., 2013)

Delta^5F has visible | adult stage phenotype, enhanceable by Kap-α3^D93

(Sachan et al., 2013)

Delta^5F has visible | adult stage phenotype, enhanceable by Kap-α3^D165

(Sachan et al., 2013)

Enhancer of

Statement

Reference

Delta^5F is an enhancer of visible | dominant phenotype of N^ANK.sev

(Matsuno et al., 1997)

Delta^5F is an enhancer of visible phenotype of N^act.sev

(Matsuno et al., 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^5F has wing vein phenotype, enhanceable by Kap-α3^D165

(Sachan et al., 2013)

Delta^5F has wing vein phenotype, enhanceable by Kap-α3^S033513

(Sachan et al., 2013)

Delta^5F has wing vein phenotype, enhanceable by Kap-α3^D93

(Sachan et al., 2013)

Enhancer of

Statement

Reference

Delta^5F is an enhancer of cone cell phenotype of N^ANK.sev

(Matsuno et al., 1997)

Delta^5F is an enhancer of photoreceptor cell R7 phenotype of N^ANK.sev

(Matsuno et al., 1997)

Delta^5F is an enhancer of photoreceptor cell R3 phenotype of N^act.sev

(Matsuno et al., 1997)

Delta^5F is an enhancer of photoreceptor cell R4 phenotype of N^act.sev

(Matsuno et al., 1997)

Delta^5F is an enhancer of photoreceptor cell R7 phenotype of N^act.sev

(Matsuno et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The wing vein deltas and thickening observed in Dl^5F heterozygous adult flies are exacerbated by combination with single copy of any of the following alleles: Kap-α3^D93, Kap-α3^D165 or Kap-α3^S033513.

(Sachan et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Nusslein-Volhard.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Delta^5F

Dl^5F102

(Yamakawa et al., 2018, Takashima et al., 2002, Go and Artavanis-Tsakonas, 1998, Matsuno et al., 1997, Bender et al., 1993, Vassin and Campos-Ortega, 1987, Lehmann et al., 1983)

Dl^5F

(Sachan et al., 2015, Sachan et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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