Heterozygous adults have wild-type wings.
The temperature sensitive heterozygous combination, Dlvi1/Dl6B leads to animals that exhibit a ISNb axon bypass phenotype. These axons reach their targets via an aberrant trajectory, in which ISNb axons remain associated with the ISN. About 23% of hemisegments are affected. The formation of neuromuscular synapses to ventral longitudinal muscles occur as efficiently in mutant animals than in controls. Other kinds of ISNb misrouting phenotypes are seen at a low frequency. However gross stalling of ISNb axons is not seen, nor are defects in muscle development.
Abnormal microtubule organisation is seen in Dlvi1/Dl6B oocytes.
Dl6B/Dlvi1 embryos show a great reduction in egg laying at the restrictive temperature (32oC). Mislocalization of bcd to the posterior pole of the oocyte and excess of polar cells were evident.
Heterozygotes have extreme extra microchaetae phenotypes.
Homozygous adults exhibit a high penetrance of tarsal segments 3 and 4 fusion.
Homozygous viable. Slight δ-like thickenings at posterior tips of wing veins 2, 3, 4 and 5; roughening of eye. Dlvi1 homozygotes also show shortening and frequent fusion of tarsal segments. A few homozygous embryos fail to hatch, showing patchy neuralization in cephalic and ventral territories. Dlvi1/+ normal. Trans heterozygotes with dominant alleles show extreme wing, eye and tarsal abnormalities.