FB2025_01 , released February 20, 2025
Allele: Dmel\dl4
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General Information
Symbol
Dmel\dl4
Species
D. melanogaster
Name
FlyBase ID
FBal0002646
Feature type
allele
Associated gene
Dmel\dl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Isoda et al., 1992)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987, Simpson, 1983)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      dl1/dl4 flies show one ectopic macrochaeta in 39% of heminota analysed at 18[o]C (this phenotype is not seen at 25[o]C).

      Heterozygous flies lack bristles in the lateral notum in 25% of heminota at 18[o]C.

      (Ayyar et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      dl[+]/dl4 is a suppressor | partially of abnormal immune response phenotype of wntDKO1

      (Gordon et al., 2005)

      dl4/dl1 is a suppressor of abnormal immune response phenotype of wntDKO1

      (Gordon et al., 2005)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Jurgens.

      (Simpson, 1983)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (17)