dnc1/
dncML adults show a significant reduction in performance index in an aversive olfactory learning assay compared to control flies.
dncML homozygous and
dncM14/
dncML heterozygous mutants exhibit an increase in the number of naturally occurring synaptopods at the type II endings. This increase is eliminated in a
Dp(1;2)51b background.
Mutant flies show a significant reduction in the number of rest hours per 24 hours compared to controls.
Some
dncML flies are arrhythmic with respect to locomotor activity (only 63.16% are rhythmic).
Flies have a low learning score (0.15) in an olfactory classical conditioning paradigm. Homozygous females are sterile. Fertility is restored to approximately 50% if
dnchs.PD is expressed using heat shock.
The point of maximal phase delay of the light induced phase response curve (PRC) differs significantly from that of wild type and the circadian period is significantly shorter.
Flies transformed with the P{dnchs.P} or P{rat\dnchs.P} construct display increased learning scores. Reduced learning and memory.