Allele Dmel\Doa³

General Information
Symbol	Dmel\Doa³	Species	D. melanogaster
Name		FlyBase ID	FBal0002721
Feature type	allele	Associated gene	Dmel\Doa
Also Known As	Doa^EMS-1

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Genes Doa
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Rabinow and Birchler, 1989)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	cell death defective (with Doa^EMS-C) (Kpebe and Rabinow, 2008) lethal \| recessive (Rabinow and Birchler, 1989) visible \| adult stage (with Doa^EMS-C) (Kpebe and Rabinow, 2008) visible \| dominant (Rabinow and Birchler, 1990)
Phenotype Manifest In
	leg (with Doa^EMS-C) (Kpebe and Rabinow, 2008)
Detailed Description
	Statement Reference In Doa[EMS-C]/Doa[3] mutant flies the leg segments distal to the first tarsus are often missing or are necrotic. The femur and claws form normally. Doa[7]/Doa[3] mutants where the Doa[7] allele is from the mother are viable. When the Doa[3] allele comes from the mother there are no survivors. In Doa[3]/Doa[Su(Mrt9)] mutants where the Doa[3] allele is from the mother the flies have small, rough eyes. When the Doa[Su(Mrt9)] allele comes from the mother there are no survivors. In Doa[3]/Doa[γ3E] mutants where the Doa[3] allele is from the mother only males are recovered and these flies have darkened areas in the wing veins. When the Doa[γ3E] allele comes from the mother there are no survivors. (Kpebe and Rabinow, 2008) Eye colour: darker than apricot in males. (Rabinow and Birchler, 1989)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference Doa³ is an enhancer of phenotype of w^sp55 (Rabinow and Birchler, 1989)
NOT Enhancer of
Statement Reference Doa³ is a non-enhancer of phenotype of w^a2 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^a3 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^a4 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^a57i11 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^a58l (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^a59k1 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^apl (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^bf2 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^bf (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^bl (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^Bwx (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^co (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^col (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^e2 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^E (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^e (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^ec3 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^h (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of wⁱ (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR1 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR2 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR3 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR4 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR5 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^IR6 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^mo (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^r (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^sat (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^sp2 (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^sp81d (Rabinow and Birchler, 1989) Doa³ is a non-enhancer of phenotype of w^zm (Rabinow and Birchler, 1989)
Suppressor of
Statement Reference Doa³ is a suppressor of phenotype of w^a (Rabinow and Birchler, 1989) Doa³ is a suppressor of phenotype of w^aM (Rabinow and Birchler, 1989) Doa³ is a suppressor of phenotype of w^aR84h (Rabinow and Birchler, 1989)
NOT Suppressor of
Statement Reference Doa³ is a non-suppressor of phenotype of w^a2 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^a3 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^a4 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^a57i11 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^a58l (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^a59k1 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^apl (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^bf2 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^bf (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^bl (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^Bwx (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^co (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^col (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^e2 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^E (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^e (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^ec3 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^h (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of wⁱ (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR1 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR2 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR3 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR4 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR5 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^IR6 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^mo (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^r (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^sat (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^sp2 (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^sp81d (Rabinow and Birchler, 1989) Doa³ is a non-suppressor of phenotype of w^zm (Rabinow and Birchler, 1989)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	1156 y¹ w^a; Doa³/TM3, Ser¹
Kyoto	106231 y¹ w^a; Doa³/TM3, Ser¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Doa³ (Christensen et al., 2009.5.6, Christensen et al., 2009.5.6, Ambrus et al., 2009) Doa^EMS1 (Peng and Mount, 1990, ) Doa^EMS-1 (Rabinow and Birchler, 1989, Kpebe and Rabinow, 2008)
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Ambrus et al., 2009, Genetics 183(1): 79--92 Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila. [FBrf0209056] Kpebe and Rabinow, 2008, Genetics 179(4): 1973--1987 Dissection of darkener of apricot kinase isoform functions in Drosophila. [FBrf0205853] Peng and Mount, 1990, Genetics 126: 1061--1069 Characterization of enhancer-of-white-apricot in Drosophila melanogaster. [FBrf0051917] Rabinow and Birchler, 1990, Genet. Res. (Camb.) 55: 141--151 Interactions among modifiers of retrotransposon-induced alleles of the white locus of Drosophila melanogaster. [FBrf0051869] Rabinow and Birchler, 1989, EMBO J. 8: 879--889 A dosage-sensitive modifier of retrotransposon-induced alleles of the Drosophila white locus. [FBrf0049635]
Personal communication to FlyBase	Christensen et al., 2009.5.6, Isolation and characterization of Df(3R)BSC789. Isolation and characterization of Df(3R)BSC789. [FBrf0207875] Christensen et al., 2009.5.6, Isolation and characterization of Df(3R)BSC806. Isolation and characterization of Df(3R)BSC806. [FBrf0207914]

Allele Dmel\Doa3

Allele Dmel\Doa³