FlyBase Allele Report: Dmel\dor[22]

General Information

Symbol

Dmel\dor²²

Species

D. melanogaster

Name

FlyBase ID

FBal0002750

Feature type

allele

Associated gene

Dmel\dor

Associated Insertion(s)

Carried in Construct

Also Known As

l(1)t¹⁸⁷, dor^lt187, dor^t187

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Belyaeva et al., 1982)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

lethal - all die before end of larval stage

(Biyasheva et al., 1985)

lethal - all die before end of larval stage | recessive

(Belyaeva et al., 1982)

lethal - all die before end of prepupal stage

(Georgel et al., 1991)

some die during larval stage

(Biyasheva et al., 1985)

some die during larval stage | recessive

(Belyaeva et al., 1982)

some die during prepupal stage | recessive

(Georgel et al., 1991)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygotes displays defective puffing patterns, can be restored to wild type patterns by in vitro incubation in ecdysterone.

(Biyasheva et al., 1985)

Dying larvae have melanotic pseudotumours.

(Belyaeva et al., 1982)

When the salivary glands of homozygotes for dor²², an allele that causes death in the third larval instar with no signs of ecdysone induction, were incubated with ecdysterone, the development of puffs was restored (Biyasheva, Belyaeva, and Zhimulev, 1985).

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Salivary gland chromosomes of homozygotes show no signs of developmental puffs. Incubation of mutant cells with ecdysterone restores developmental puff formation.

(Biyasheva et al., 1985)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

dor²²

dor^lt187

(Solovyeva and Belyaeva, 1989, Biyasheva et al., 1985, Belyaeva et al., 1980)

dor^t187

(Maschat et al., 1991, Deutsch et al., 1989)

l(1)t187

(Antoniewski et al., 1994)

l(1)t¹⁸⁷

(Huet et al., 1996, Meister and Richards, 1996, Georgel et al., 1991)

lt187

(Belyaeva et al., 1982)

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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