A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\dpov1

General Information
SymbolDmel\dpov1SpeciesD. melanogaster
Nameoblique vortexFlyBase IDFBal0002834
Feature typealleleAssociated geneDmel\dp
Allele class
Mutagenspontaneous
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Description
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FB2013_03
FB2013_02
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hide Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Insertion of a blood element into intron 11.
Caused by insertion
Carried on aberration
Cytology
hide Phenotypic Data
hide Phenotypic Class
hide Phenotype Manifest In
adult thorax & adult epidermis
 
hide Detailed Description
Statement
Reference
Mutant flies show significantly increased survival compared to wild-type flies after infection with E. chaffeensis. Bacterial replication is significantly reduced in the mutant flies compared to wild type.
Mutant flies have anterior indentations in the notum epidermis.
"ov" class allele.
dp[ov1] embryos do not show defects in tracheal tube length and do not show breaks in the tracheal branches.
dpTC4/dpov1 flies have "lopped" and "vortex" phenotypes. Body and leg size are reduced.
Oblique wing phenotype (o). Thoracic vortex phenotype (v). Wings reduced one-third and have oblique truncation; angle between veins L2 and L3 widened; intercrossvein distances shortened; marginal vein intact; two vortices with whorls of hairs in dorsocentral region; dorsocentral bristles medially displaced; vortex expression in most flies at 26oC; comma effect in anterior thorax also present in most flies at 26oC. At lower temperatures, wing effect persists, but thorax appears normal. Body and leg size normal except at temperatures above 28oC, when they are somewhat reduced. RK1.
 
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Linkouts
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hide Phenotypic Class
hideEnhanced by
Statement
Reference
dpov1 has visible phenotype, enhanceable by chas1
hideEnhancer of
Statement
Reference
dpov1 is an enhancer of visible phenotype of chas1
hide Phenotype Manifest In
hideEnhanced by
Statement
Reference
dpov1 has mesothoracic tergum phenotype, enhanceable by chas1
hideSuppressed by
Statement
Reference
dpov1/dpo2 has wing phenotype, suppressible by su(dpov)1
dpov1/dpo2 has wing phenotype, suppressible by su(dpov)2
dpov1/dpo2 has wing phenotype, suppressible by su(dpov)3
dpov1 has adult thorax phenotype, suppressible by su(dpov)1
dpov1 has wing phenotype, suppressible by su(dpov)1
dpov1 has wing phenotype, suppressible by su(dpov)2
dpov1 has wing phenotype, suppressible by su(dpov)3
hideNOT suppressed by
Statement
Reference
dpov1 has adult thorax phenotype, non-suppressible by su(dpov)2
dpov1 has adult thorax phenotype, non-suppressible by su(dpov)3
dpv2/dpov1 has adult thorax phenotype, non-suppressible by su(dpov)1
dpv2/dpov1 has adult thorax phenotype, non-suppressible by su(dpov)2
dpv2/dpov1 has adult thorax phenotype, non-suppressible by su(dpov)3
hideEnhancer of
Statement
Reference
dpov1 is an enhancer of mesothoracic tergum phenotype of chas1
hide Additional Comments
hide Genetic Interactions
Statement
Reference
chas[1] dp[ov1] double mutants show enhanced indentations of the anterior notum epidermis and enhanced planar polarity defects compared to either single mutant.
The tracheal tube length defects caused by vari[f00033] are enhanced if the embryos are also mutant for dp[ov1].
The oblique wing phenotype is suppressed in homozygous su(dpov)1, su(dpov)2 or su(dpov)3 flies. The vortex (thoracic invagination) phenotype is suppressed in homozygous su(dpov)1 flies. The wing phenotype of dpov1/dpo2 flies is totally suppressed by su(dpov)1, su(dpov)2 or su(dpov)3.
hide Xenogenetic Interactions
Statement
Reference
hide Complementation & Rescue Data
Fails to complement
Comments
hide Stocks ( 166 )
Bloomington
Kyoto
105826
hide Notes on Origin
Discoverer
Morgan, 16 Oct. 1918.
hide Comments
Aspartate transcarbamylase (ATCase), orotate phosphoribosyltransferase (OPRTase) and orotidine-5'-phosphate decarboxylase (ODCase) activity is elevated in dpov1 flies and normalised in su(dpov)1 dpov1 flies.
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Other Crossreferences
Linkouts
hide Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym
dpov
dpovCB1
 
Name Synonym
oblique vortex
 
Secondary FlyBase IDs
hide References ( 17 )
Research paper
Von Ohlen et al., 2012, Infect. Immun. 80(10): 3576--3586
Identification of Critical Host Mitochondrion-Associated Genes during Ehrlichia chaffeensis Infections. [FBrf0219421]
Carmon et al., 2010, PLoS ONE 5(8): e12319
A Molecular Analysis of Mutations at the Complex dumpy Locus in Drosophila melanogaster. [FBrf0211710]
Swanson et al., 2009, Genetics 181(4): 1281--1290
Drosophila convoluted/dALS is an essential gene required for tracheal tube morphogenesis and apical matrix organization. [FBrf0207797]
Coelho et al., 2005, Genetics 171(2): 597--614
A genetic screen for dominant modifiers of a small-wing phenotype in Drosophila melanogaster identifies proteins involved in splicing and translation. [FBrf0190712]
Kjaer, 1989, Hereditas 110(1): 7--12
A new X-bound suppressor mutation in Drosophila melanogaster suppressor of dumpy. [FBrf0050051]
Sederoff, 1967, Nature 216: 1348--1349
Rare pseudoallelic crossover between two phenotypically identical alleles at a restricted sublocus of dumpy in Drosophila melanogaster. [FBrf0018916]
Carlson, 1956, D. I. S. 30: 70
[New mutants report.] [FBrf0094323]
Morgan, 1929, Publs Carnegie Instn 399: 169--199
Contributions to the genetics of Drosophila simulans and Drosophila melanogaster. [FBrf0001868]
Supplementary material
Olguín et al., 2011, Curr. Biol. 21(3):
Supplemental Information. [FBrf0213857]
Personal communication to FlyBase
Deal et al., 2004.7.8, Isolation and characterization of Df(2L)BSC53.
Isolation and characterization of Df(2L)BSC53. [FBrf0178896]
Roote, 2004.6.24, Cam Dps.
Cam Dps. [FBrf0178882]
Deal et al., 2003.9.17, Isolation and characterization of Df(2L)BSC41.
Isolation and characterization of Df(2L)BSC41. [FBrf0161614]
Bloomington Drosophila Stock Center, 2001.8.28, Balancer Variants.
Balancer Variants. [FBrf0138610]
Deal et al., 2001.8.1, Isolation and Characterization of Df(2L)BSC6.
Isolation and Characterization of Df(2L)BSC6. [FBrf0137514]
Roote, 2000.6.13, New P derivatives.
New P derivatives. [FBrf0129261]
FlyBase analysis
FlyBase Curators, 2006-, Balancer summary information.
Balancer summary information. [FBrf0189689]
Book
Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
Genetic variations of Drosophila melanogaster. [FBrf0020044]