Allele Dmel\dpp^d-ho

General Information
Symbol	Dmel\dpp^d-ho	Species	D. melanogaster
Name		FlyBase ID	FBal0002997
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\dpp

Allele class
Mutagen	spontaneous
Nature of the Allele
Allele class
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference 2.7kb deletion. (Irish and Gelbart, 1987) 3kb deletion of sequences 23kb 3' of the dpp transcription unit. (Masucci et al., 1990)
Assay mode
Carried on aberration	Dp(2;2)Cam13 (Roote, 2004.6.24) T(2;3)ast^rv1 (Lewis, 1945) C(2L)RM-VT1
Cytology	Polytene chromosomes normal. Polytene chromosomes normal. (Gelbart, 1982) Polytene chromosomes normal. (Segal and Gelbart, 1985)
Phenotypic Data
Phenotypic Class
	visible (Gelbart, 1982) visible \| recessive (Irish and Gelbart, 1987)
Phenotype Manifest In
	wing (Horsfield et al., 1998, Gelbart, 1982)
Detailed Description
	Statement Reference Wings extended at right angles to body. RK1. Wings are held out laterally to the long axis of the body. (Spencer et al., 1982) Held-out wings. The wings are held out laterally instead of in line with the longitudinal axis of the body. Transheterozygotes with dpp^hr4 exhibit normally oriented wings. (Gelbart, 1982) Held out wing phenotype. (Irish and Gelbart, 1987) z¹ product subliminally inhibits the complementation of dpp^hr4 and dpp^d-ho. The effect is only seen when compounded by the particular effects of rearrangements on synapsis. (Smolik-Utlaut and Gelbart, 1987) Complete wings, reduction of sensilla on the dorsal radius from 25 to 8 and an additional fold. (Bryant, 1988) Held out wing, defects in sensilla campaniforma on the wing blade. (Masucci et al., 1990) dpp^s1 dpp^d-ho double mutant chromosome partially suppresses the penetrance of the hh^Mrt phenotype. (Felsenfeld and Kennison, 1995) dpp^hr4/dpp^d-ho transheterozygotes show a wild type wing phenotype in an otherwise normal genetic background. (Sanicola et al., 1995) Held out wings, no noticeable eye roughening. (Horsfield et al., 1998)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference dpp^d-ho is a suppressor of visible phenotype of os^GMR.PB (Bach et al., 2003)
Other
Statement Reference DTD45.10^45.10, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.6^46.6, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) Df(2L)DTD52-D51, In(2LR)DTD11, dpp^d-ho/dpp^hr4 has visible phenotype (Gelbart, 2001.4.19) dpp^d-ho/dpp^hr4, lilli^a16 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.5^46.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.1^45.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.8^46.8, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD44.4^44.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) Ab(?)DTD44.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) Ab(?)DTD45.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) DTD44.3^44.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD44.5^44.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.11^45.11, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.7^45.7, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.8^45.8, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) Df(2L)C144, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) Dp(2;2)DTD45.12, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2L)DTD46.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD45.6, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD46.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD46.9, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD44.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.9, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD46.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD46.7, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;4)DTD43.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2L)DTD42.0, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001)
Phenotype Manifest In
Enhanced by
Statement Reference dpp^d-ho has phenotype, enhanceable by tld¹⁴ (Raftery et al., 1995)
NOT suppressed by
Statement Reference dpp^d-ho has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968)
Suppressor of
Statement Reference dpp^d-ho is a suppressor of eye phenotype of os^GMR.PB (Bach et al., 2003) dpp^d-ho/dpp^d-ho is a suppressor of wing vein \| ectopic phenotype of Snr1^R3/Snr1^E1 (Marenda et al., 2004, Marenda et al., 2004) dpp^d-ho/tkv^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/put^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/Mad^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) Med^unspecified/dpp^d-ho is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/shn^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/dpp^d12 is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/dpp^hr4 is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998)
Other
Statement Reference DTD45.10^45.10, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.6^46.6, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) dpp^d-ho/dpp^hr4, en⁹⁶ has wing phenotype (Sanicola et al., 1995, Sanicola et al., 1995) Df(2L)DTD52-D51, In(2LR)DTD11, dpp^d-ho/dpp^hr4 has wing phenotype (Gelbart, 2001.4.19) dpp^d-ho/dpp^hr4, lilli^a16 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.5^46.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.1^45.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.8^46.8, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD44.4^44.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) Ab(?)DTD44.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) Ab(?)DTD45.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) DTD44.3^44.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD44.5^44.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.11^45.11, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.7^45.7, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.8^45.8, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) Df(2L)C144, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) Dp(2;2)DTD45.12, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2L)DTD46.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD45.6, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD46.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD46.9, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD44.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.9, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD46.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD46.7, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;4)DTD43.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2L)DTD42.0, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001)
Additional Comments
Genetic Interactions
Statement Reference The dpp^hr4/dpp^d-ho phenotype is dominantly enhanced by en⁹⁶ (In(2R)DTD96), to cause heldout wings. (Sanicola et al., 1995) dpp^d-ho/dpp^hr4 shows heldout wings in combination with In(2L)DTD42.0, T(2;4)DTD43.1, T(2;3)DTD43.3, T(2;3)DTD43.4, T(2;3)DTD43.5, T(2;3)DTD44.1, Ab(?)DTD44.2, DTD44.3^44.3, DTD44.4^44.4, DTD44.5^44.5, DTD45.1^45.1, Ab(?)DTD45.2, T(2;3)DTD45.3, T(2;3)DTD45.4, T(2;3)DTD45.5, In(2LR)DTD45.6, DTD45.7^45.7, DTD45.8^45.8, T(2;3)DTD45.9, DTD45.10^45.10, DTD45.11^45.11, Dp(2;2)DTD45.12, In(2LR)DTD46.2, In(2L)DTD46.3, T(2;3)DTD46.4, DTD46.5^46.5, DTD46.6^46.6, T(2;3)DTD46.7, DTD46.8^46.8, In(2LR)DTD46.9, Df(2L)C144 or lilli^a16. (Su et al., 2001) In(2LR)DTD52, dpp^d-ho/In(2LR)DTD11, dpp^hr4 flies have wild-type wing posture. Df(2L)DTD52-D51, dpp^d-ho/In(2LR)DTD11, dpp^hr4 flies have a heldout wing posture. (Gelbart, 2001.4.19)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments	Allele class: d-ho
Stocks ( 38 )
Bloomington	308 dpp^d-ho 398 dpp^s1 dpp^d-ho 1343 In(2LR)DTD51, dpp^d-ho/CyO 221 ast¹ dpp^d-ho cl¹ 1446 ast¹ dpp^d-ho dp^o2 97 Df(2L)JS32, dpp^d-ho/CyO, P{sevRas1.V12}FK1 1567 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11 217 al¹ S¹ ast¹ dpp^d-ho/SM1
Kyoto	103268 Df(2L)JS32, dpp^d-ho / SM6a 106316 ast¹ dpp^d-ho dp^o2 108890 Df(2L)JS32, dpp^d-ho/CyO, P{sevRas1.V12}FK1 106390 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11
	More stocks available...
Notes on Origin
Discoverer	Novitski, July 1935.

Comments
	Class I dpp allele. (Spencer et al., 1982) dpp class I allele. (Segal and Gelbart, 1985) Class I allele. (Smolik-Utlaut and Gelbart, 1987)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	dpp^d-ho dpp^ho2 (Smolik-Utlaut and Gelbart, 1987, Segal and Gelbart, 1985, Gelbart, 1982) dpp^ho (Irish and Gelbart, 1987, Gelbart, 1982) ho (Lewis, 1945, ) ho2
Name Synonym	heldout (Winchester, 2004, Anderson, 1991, Crow et al., 2006)
Secondary FlyBase IDs
	FBal0031070
References ( 33 )

Generate a list of	All references relating to this allele ( 33 )

List References by type	Research paper ( 22 ) Review ( 2 ) Personal communication to FlyBase ( 5 ) Obituary ( 1 ) Book review ( 1 ) Biography ( 1 ) Book ( 1 )
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Allele Dmel\dppd-ho

Allele Dmel\dpp^d-ho