Allele Dmel\dpp^d-ho

General Information
Symbol	Dmel\dpp^d-ho	Species	D. melanogaster
Name		FlyBase ID	FBal0002997
Feature type	allele	Associated gene	Dmel\dpp
Also Known As	dpp^ho2, dpp^ho

Allele class
Mutagen	spontaneous
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	spontaneous
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference 3kb deletion of sequences 23kb 3' of the dpp transcription unit. (Masucci et al., 1990) 2.7kb deletion. (Irish and Gelbart, 1987)
Carried on aberration	C(2L)RM-VT1 Dp(2;2)Cam13 (Roote, 2004.6.24) T(2;3)ast^rv1 (Lewis, 1945)
Cytology	Polytene chromosomes normal. Polytene chromosomes normal. (Gelbart, 1982) Polytene chromosomes normal. (Segal and Gelbart, 1985)
Phenotypic Data
Phenotypic Class
	visible (Gelbart, 1982) visible \| recessive (Irish and Gelbart, 1987)
Phenotype Manifest In
	wing (Horsfield et al., 1998, Gelbart, 1982)
Detailed Description
	Statement Reference Held out wings, no noticeable eye roughening. (Horsfield et al., 1998) dpp^s1 dpp^d-ho double mutant chromosome partially suppresses the penetrance of the hh^Mrt phenotype. (Felsenfeld and Kennison, 1995) dpp^hr4/dpp^d-ho transheterozygotes show a wild type wing phenotype in an otherwise normal genetic background. (Sanicola et al., 1995) Held out wing, defects in sensilla campaniforma on the wing blade. (Masucci et al., 1990) Complete wings, reduction of sensilla on the dorsal radius from 25 to 8 and an additional fold. (Bryant, 1988) Held out wing phenotype. (Irish and Gelbart, 1987) z¹ product subliminally inhibits the complementation of dpp^hr4 and dpp^d-ho. The effect is only seen when compounded by the particular effects of rearrangements on synapsis. (Smolik-Utlaut and Gelbart, 1987) Held-out wings. The wings are held out laterally instead of in line with the longitudinal axis of the body. Transheterozygotes with dpp^hr4 exhibit normally oriented wings. (Gelbart, 1982) Wings are held out laterally to the long axis of the body. (Spencer et al., 1982) Wings extended at right angles to body. RK1.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference dpp^d-ho/dpp[+] is a suppressor of visible phenotype of Scer\GAL4^tub.PU, csw^{N308D.Scer\UAS.P\T} (Oishi et al., 2006) dpp^d-ho is a suppressor of visible phenotype of os^GMR.PB (Bach et al., 2003)
Other
Statement Reference Ab(?)DTD44.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) Ab(?)DTD45.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) Df(2L)C144, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) Df(2L)DTD52-D51, In(2LR)DTD11, dpp^d-ho/dpp^hr4 has visible phenotype (Gelbart, 2001.4.19) Dp(2;2)DTD45.12, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) dpp^d-ho/dpp^hr4, lilli^a16 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD44.3^44.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD44.4^44.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD44.5^44.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.1^45.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.7^45.7, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.8^45.8, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.10^45.10, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD45.11^45.11, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.5^46.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.6^46.6, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) DTD46.8^46.8, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001, Su et al., 2001) In(2L)DTD42.0, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2L)DTD46.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD45.6, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD46.2, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) In(2LR)DTD46.9, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD43.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD44.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.3, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.5, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD45.9, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD46.4, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;3)DTD46.7, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001) T(2;4)DTD43.1, dpp^d-ho/dpp^hr4 has visible phenotype (Su et al., 2001)
Phenotype Manifest In
Enhanced by
Statement Reference dpp^d-ho has phenotype, enhanceable by tld¹⁴ (Raftery et al., 1995)
NOT suppressed by
Statement Reference dpp^d-ho has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968)
Suppressor of
Statement Reference dpp^d-ho/dpp[+] is a suppressor of wing vein \| ectopic phenotype of Scer\GAL4^tub.PU, csw^{N308D.Scer\UAS.P\T} (Oishi et al., 2006) dpp^d-ho/dpp^d12 is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/dpp^d-ho is a suppressor of wing vein \| ectopic phenotype of Snr1^R3/Snr1^E1 (Marenda et al., 2004, Marenda et al., 2004) dpp^d-ho/dpp^hr4 is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/Mad^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/put^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/shn^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho/tkv^unspecified is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho is a suppressor of eye phenotype of CycE^JP (Horsfield et al., 1998) dpp^d-ho is a suppressor of eye phenotype of os^GMR.PB (Bach et al., 2003) Med^unspecified/dpp^d-ho is a suppressor of phenotype of CycE^JP (Horsfield et al., 1998)
Other
Statement Reference Ab(?)DTD44.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) Ab(?)DTD45.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) Df(2L)C144, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) Df(2L)DTD52-D51, In(2LR)DTD11, dpp^d-ho/dpp^hr4 has wing phenotype (Gelbart, 2001.4.19) Dp(2;2)DTD45.12, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) dpp^d-ho/dpp^hr4, en⁹⁶ has wing phenotype (Sanicola et al., 1995, Sanicola et al., 1995) dpp^d-ho/dpp^hr4, lilli^a16 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD44.3^44.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD44.4^44.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD44.5^44.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.1^45.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.7^45.7, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.8^45.8, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.10^45.10, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD45.11^45.11, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.5^46.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.6^46.6, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) DTD46.8^46.8, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001, Su et al., 2001) In(2L)DTD42.0, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2L)DTD46.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD45.6, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD46.2, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) In(2LR)DTD46.9, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD43.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD44.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.3, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.5, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD45.9, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD46.4, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;3)DTD46.7, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001) T(2;4)DTD43.1, dpp^d-ho/dpp^hr4 has wing phenotype (Su et al., 2001)
Additional Comments
Genetic Interactions
Statement Reference In(2LR)DTD52, dpp^d-ho/In(2LR)DTD11, dpp^hr4 flies have wild-type wing posture. Df(2L)DTD52-D51, dpp^d-ho/In(2LR)DTD11, dpp^hr4 flies have a heldout wing posture. (Gelbart, 2001.4.19) dpp^d-ho/dpp^hr4 shows heldout wings in combination with In(2L)DTD42.0, T(2;4)DTD43.1, T(2;3)DTD43.3, T(2;3)DTD43.4, T(2;3)DTD43.5, T(2;3)DTD44.1, Ab(?)DTD44.2, DTD44.3^44.3, DTD44.4^44.4, DTD44.5^44.5, DTD45.1^45.1, Ab(?)DTD45.2, T(2;3)DTD45.3, T(2;3)DTD45.4, T(2;3)DTD45.5, In(2LR)DTD45.6, DTD45.7^45.7, DTD45.8^45.8, T(2;3)DTD45.9, DTD45.10^45.10, DTD45.11^45.11, Dp(2;2)DTD45.12, In(2LR)DTD46.2, In(2L)DTD46.3, T(2;3)DTD46.4, DTD46.5^46.5, DTD46.6^46.6, T(2;3)DTD46.7, DTD46.8^46.8, In(2LR)DTD46.9, Df(2L)C144 or lilli^a16. (Su et al., 2001) The dpp^hr4/dpp^d-ho phenotype is dominantly enhanced by en⁹⁶ (In(2R)DTD96), to cause heldout wings. (Sanicola et al., 1995)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments	Allele class: d-ho
Stocks ( 29 )
Bloomington	308 dpp^d-ho 398 dpp^s1 dpp^d-ho 97 Df(2L)JS32, dpp^d-ho/CyO, P{sevRas1.V12}FK1 1567 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11 4744 Dp(2;2)Cam17, dpp^d-ho cn¹ bw¹/CyO 3391 Dp(2;2)Cam13, Dp(1;2)TE23CD, net¹ dpp^d-ho/CyO
Kyoto	103268 Df(2L)JS32, dpp^d-ho / SM6a 106316 ast¹ dpp^d-ho dp^o2 108890 Df(2L)JS32, dpp^d-ho/CyO, P{sevRas1.V12}FK1 106390 Df(2L)JS17, dpp^d-ho/CyO, P{en1}wg^en11 107856 Dp(2;2)Cam17, dpp^d-ho cn¹ bw¹/CyO 107063 Dp(2;2)S, dpp^d-ho/In(2L)Cy, In(2R)Cy, E(S)¹
	More stocks available...
Notes on Origin
Discoverer	Novitski, July 1935.

Comments
	Class I allele. (Smolik-Utlaut and Gelbart, 1987) dpp class I allele. (Segal and Gelbart, 1985) Class I dpp allele. (Spencer et al., 1982)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	dpp^d-ho (Oishi et al., 2006) dpp^dho (Twombly et al., 2009) dpp^ho2 (Smolik-Utlaut and Gelbart, 1987, Segal and Gelbart, 1985, Gelbart, 1982) dpp^ho (Irish and Gelbart, 1987, Gelbart, 1982) ho (Lewis, 1945, ) ho2
Name Synonym	heldout (Winchester, 2004, Anderson, 1991, Crow et al., 2006)
Secondary FlyBase IDs
	FBal0031070
References ( 35 )

Generate a list of	All references relating to this allele ( 35 )

List References by type	Research paper ( 24 ) Review ( 2 ) Personal communication to FlyBase ( 5 ) Obituary ( 1 ) Book review ( 1 ) Biography ( 1 ) Book ( 1 )
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Allele Dmel\dppd-ho

Allele Dmel\dpp^d-ho