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General Information
Symbol
Dmel\dpps8
Species
D. melanogaster
Name
FlyBase ID
FBal0003078
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Polytene chromosomes normal.
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
dpps4/dpps8 flies lack the distal ends of wing vein LII, LIV and LV.
A posterior clone runs along the antero-posterior boundary until it reaches a gap in wing vein 4 (a region sensitive to lack of dpp) where the border of the clone becomes irregular.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference
dpps4/dpps8 has wing vein phenotype, enhanceable by tkv1/tkv8
Suppressor of
Statement
Reference
dpps4/dpps8 is a suppressor of phenotype of tkv1/tkv8
dpps4/dpps8 is a suppressor of wing vein | ectopic phenotype of rhohs.PSt
dpps4/dpps8 is a suppressor of wing vein | ectopic phenotype of Ras64BAct5C.PC
Other
Additional Comments
Genetic Interactions
Statement
Reference
Double heterozygous dpps8; fd68A44 mutants exhibit almost 100% viability. Double heterozygous dpps8; fd68A16 mutants exhibit almost 100% viability.
Double mutant clones with nub1 or nub2 cause dramatic reduction of cell number in the wing pouch.
The dpp shortvein phenotype is strongly enhanced, and the tkv phenotype is suppressed, in dpps4 tkv1/dpps8 tkv8 double mutant flies. The rhohs.PSt and Ras64BAct5C.PC ectopic vein phenotypes are suppressed in combination with dpps4/dpps8. dpps4/dpps8 NAx-1 double mutant flies show pronounced wing vein loss. The dpp loss of vein phenotype is epistatic in dpps4/dpps8 Nnd-3 double mutants, and the vein thickening characteristic of Nnd-3 is eliminated.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Allele class: shv-lnc
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)