FlyBase Allele Report: Dmel\dsx[1]

General Information

Symbol

Dmel\dsx¹

Species

D. melanogaster

Name

FlyBase ID

FBal0003154

Feature type

allele

Associated gene

Dmel\dsx

Associated Insertion(s)

Carried in Construct

Also Known As

dsx

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Ota et al., 1981)

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | female | recessive

(Kopp et al., 2000)

abnormal courtship behavior | male

(Lee and Hall, 2000)

abnormal courtship behavior | male | recessive

(Villella and Hall, 1996)

abnormal sex-determination

(Ota et al., 1981)

abnormal sex-determination (with dsx^GAL4.Δ2)

(Pan et al., 2011)

abnormal sex-determination | adult stage (with Df(3R)dsx3)

(Zhou et al., 2021)

abnormal sex-determination | male (with dsx^Fcons)

(Hérault et al., 2024)

abnormal sex-determination | recessive

(Li and Baker, 1998)

abnormal song (with dsx^{f00683-d07058})

(Shirangi et al., 2016)

decreased occurrence of cell division | embryonic stage (with dsx^D)

(Wawersik et al., 2005)

female fertile (with dsx^Fcons)

(Hérault et al., 2024)

visible | adult stage | male (with dsx^Fcons)

(Hérault et al., 2024)

visible | female | recessive

(Kopp et al., 2000)

Phenotype Manifest In

abdominal sternite 6

(Li and Baker, 1998)

abdominal sternite 6 | male limited (with dsx¹⁸)

(Wang et al., 2011)

adult abdominal segment 6 | male

(Waterbury et al., 1999)

adult abdominal segment 7 | ectopic | male limited (with dsx¹⁸)

(Wang et al., 2011)

adult cuticle & abdominal segment 5 | female

(Kopp et al., 2000)

adult cuticle & abdominal segment 6 | female

(Kopp et al., 2000)

epiproct

(Li and Baker, 1998)

female genitalia

(Waterbury et al., 1999)

genital disc

(Gorfinkiel et al., 2003, Sanchez et al., 2001)

genital disc (with dsx³⁴)

(Ahmad and Baker, 2002)

germline cell

(Nagoshi et al., 1995)

gonad | adult stage (with Df(3R)dsx3)

(Zhou et al., 2021)

gonad | embryonic stage (with dsx²³)

(DeFalco et al., 2004)

gonadal sheath proper primordium | female (with dsx²³)

(DeFalco et al., 2003)

gonadal sheath proper primordium | female (with dsx^D)

(DeFalco et al., 2003)

hub cell (with dsx²³)

(Le Bras and Van Doren, 2006)

male genitalia

(Waterbury et al., 1999)

prothoracic leg taste bristle chemosensory neuron | male limited (with dsx³⁴)

(Mellert et al., 2010)

Detailed Description

Statement

Reference

Under control conditions, dsx¹ adult posterior midgut clones do not show significant size differences in males and females, as compared to control clones.

(Hudry et al., 2016)

dsx¹/dsx^{f00683-d07058} males do not sing sine song and they sing less pulse song, with significant defects in inter-pulse interval, carrier frequency and amplitude, compared to heterozygous controls.

(Shirangi et al., 2016)

dsx^GAL4.Δ2/dsx¹ animals are intersex.

(Pan et al., 2011)

A partial A7-like terminal abdominal segment (similar to abdominal segment 7 found in wild-type females) forms and A6 sternite is transformed toward anterior identity in dsx¹/dsx¹⁸ trans-heterozygous males.

(Wang et al., 2011)

XY dsx¹/dsx³⁴ animals show less midline crossing by foreleg gustatory receptor neuron (GRN) axons than seen in control XY males, although they still show a much higher level of midline crossing by foreleg GRN axons than seen in control XX females. XX control females and XX dsx¹/dsx³⁴ animals show an extremely low level of midline crossing by foreleg GRN axons.

XX dsx¹/dsx^D animals do not show an increase in midline crossing by foreleg GRN axons compared to the extremely low level of midline crossing seen in control XX females.

(Mellert et al., 2010)

dsx^GAL4 produces classical dsx mutant morphological phenotypes when heterozygous with the null allele dsx¹.

(Robinett et al., 2010)

dsx¹/dsx²³ mutant gonads are masculinised with respect to hub formation (germline stem cell niche formation).

(Le Bras and Van Doren, 2006)

dsx¹/dsx²³ mutant embryonic gonads appear fully masculinised.

(DeFalco et al., 2004)

In the somatic gonad, stage 15 male dsx¹/dsx²³ mutant embryos are indistinguishable from wild-type males. In contrast, the gonads of both stage 15 female dsx¹/dsx²³ and dsx¹/dsx^D mutant embryos exhibit a completely masculinized phenotype, in which male-specific somatic gonadal precursors are clearly present.

(DeFalco et al., 2003)

Marked clones induced in homozygous intersexual genital discs are confined to either the male or female genital primordium, indicating the existence of a cell lineage restriction. Similarly, marked clones in the male genital primordium do not cross towards the anal primordium.

(Gorfinkiel et al., 2003)

Two ectopic invaginating pockets of btl-expressing cells derived from the ventral surface of the disc are seen in the A8-derived female primordium of XX ; dsx¹/dsx³⁴ genital discs.

(Ahmad and Baker, 2002)

Both male and female genital primordia develop in mutant genital discs.

(Sanchez et al., 2001)

Females hemizygous for dsx¹ show male-type pigmentation of A5 and A6, except for a small section in the anterior and lateral part of A5.

(Kopp et al., 2000)

XY ; dsx¹ males show "normal" levels of head-to-head interactions compared to wild-type males. Homozygous males form short inter-male chains on day 5 after being grouped together, with a maximum of 3 to 4 mutant flies being involved in each chain.

(Lee and Hall, 2000)

dsx¹/dsx⁴³ females have a pheromone profile that resembles, to a first approximation, that of wild-type males. Subtle effects on viability (6-8%) are seen at 25^oC and 29^oC in flies carrying dsx^F.Hsp83 in a dsx¹/dsx⁴³ background. At 18^o to 25^oC, the genitalia are incompletely feminised, although they are clearly more feminised than the intersexual genitalia of XX dsx¹/dsx⁴³ animals. The male genital arch, which is normally found in XX dsx¹/dsx⁴³ animals, is missing although the pigmentation of abdominal segments A6 and A7 is similar to that observed in XX dsx¹/dsx⁴³ animals. The flies have mature, overfilled ovaries containing multiple late-stage eggs. At 29^oC, pigmentation and external genitalia of females carrying dsx^F.Hsp83 in a dsx¹/dsx⁴³ background resembles that of wild-type females. 10-15% of the females are rescued to fertility by a single copy of dsx^F.Hsp83. The remaining females are sterile and do not lay eggs. The reason for this sterility is unclear; the external genitalia and internal structures of the gonad closely resemble wild-type and the ovaries are morphologically normal and filled with many late-stage eggs. Males carrying dsx^F.Hsp83 in a dsx¹/+ background show no effect on abdominal pigmentation, but there is an increase in the frequency of genital rotation and other gross abnormalities of the genitalia compared to males carrying dsx^F.Hsp83 in a wild-type background. The number of bristles on abdominal segment 6 is also increased. These males have male-specific accessory glands and the gonads develop as sperm-producing testes. These males court less frequently and less aggressively than dsx¹/+ controls, and when they do court it is not sustained for long periods of time. XY flies carrying dsx^F.Hsp83 in a dsx¹/dsx⁴³ background are transformed into pseudofemales at 25^o or 29^oC. Externally, these pseudofemales have female abdominal pigmentation and female genitalia and lack sex combs. This external feminisation is fully penetrant with invariant expressivity. Internally, although a uterus is present and male-specific structures such as the accessory glands are absent, the germline and surrounding soma is underdeveloped; there are no distinct ovarioles or developing egg chambers - only amorphous germline/soma cell clusters are seen. There is a complete loss of sex combs (they are transformed into female bristles). Viability is reduced by 38-40% compared to dsx¹/dsx⁴³ males. These pseudofemales show little interest in females and perform only early mating behaviours (orientation, tapping, wing extension and vibration). Unlike wild-type females they continue to move around the chamber during copulation and flick their wings in an apparent attempt to dislodge the male.

(Waterbury et al., 1999)

5% of XY ; her¹/her¹; dsx¹/dsx¹ flies have fused intersexual dorsal-lateral anal plates. 70% of XY ; her¹/+ ; dsx¹/dsx¹ and 0% of XY ; her¹/her¹; dsx¹/+ flies have fused intersexual dorsal-lateral anal plates. The number of bristles on the 6th sternite in XY; dsx¹/dsx¹ flies is increased to the female-specific level.

(Li and Baker, 1998)

XY males show courtship sluggishness when compared to wild type siblings. Aging does not improve the courtship performance. Song pulses are similar to those of dsx⁺ males, though number and duration of song bouts are much reduced. No sine-song bouts whatsoever are generated by dsx mutants. In elicitation and rejection tests, dsx haplo-X mutants demonstrate an attractiveness that cannot be explained by general enfeeblement, such as inability to reject courtship advances.

(Villella and Hall, 1996)

No more than 26% of XX dsx^T/dsx¹ mutant pseudomales produce gonads with the most severe group 1 pseudotestes phenotype. The remaining pseudomales have a less severe phenotype, with viable germ cells. otu¹⁰ and Df(1)otu-PΔ1 cause an increase in severity of this phenotype: over 70% of the resulting gonads were of group 1.

(Nagoshi et al., 1995)

X/X; dsx¹/dsx¹ gonads are larger than female though smaller than male gonads. By third instar larvae the gonads are of the female size and do not show the morphology of spermatocytes. X/Y; dsx¹/dsx¹ and X/Y; dsx¹/dsx¹¹germ cells remain small and do not display a typical male phenotype.

(Steinmann-Zwicky, 1994)

XX dsx¹/dsx¹ and dsx¹/Df(3R)dsx15 flies do not show any male-specific courtship when paired with mature virgin females. 30% of XX and 56% of XY dsx¹ tra¹ double homozygous flies show male-specific courtship when paired with mature virgin females. 6% of XY dsx¹/dsx¹ flies and 27% of XY dsx¹/Df(3R)dsx15 flies show male-specific courtship when paired with mature virgin females. XY dsx¹/Df(3R)dsx15 flies have a reduced courtship index (compared to control males) when paired with immature male flies.

(Taylor et al., 1994)

Sex specific neuroblasts fail to undergo any postembryonic divisions in male or female larval nervous systems.

(Taylor and Truman, 1992)

Dorsal musculature does not undergo sexual transformation.

(Taylor, 1992)

vir^ts/vir^ts dsx¹/+ XX flies are sterile females with defective inner genitalia at 25^oC.

(Hilfiker and Nothiger, 1991)

XX flies have an intersex phenotype in trans with dsx⁶, dsx¹², dsx² or dsx¹³.

(Nothiger et al., 1987)

Homozygous flies are intersex, having two somewhat abnormal and incomplete sets of genitalia.

(Epper and Sanchez, 1983)

Effects both chromosomal sexes. Homozygous flies have rudimentary gonads, occasionally ovary-like gonads with some oocytes and eggs are seen in XX individuals. dsx^D/dsx¹ flies are transformed into somatically male-like animals.

(Schupbach, 1982)

Both XX and XY flies are transformed into intersexes.

(Ota et al., 1981)

strong allele; XX and XY equally affected

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

dsx^Δ, fru^P1.LexA, dsx¹, Df(3R)Exel6179 is a non-suppressor of increased occurrence of cell division | female limited | adult stage phenotype of N^KK102890, Scer\GAL4^NP7397

(Hudry et al., 2016)

Other

Statement

Reference

dsx^Fcons/dsx¹, tra^KO.Dvir-tra/tra^KO.Cherry has female semi-sterile phenotype

(Hérault et al., 2024)

Df(3R)dsx3/dsx¹, Df(3R)fru^sat15 has abnormal sex-determination | adult stage phenotype

(Zhou et al., 2021)

Dper\dsx^+t31M5, Dper\fru^+t36N18, dsx^Δ/dsx¹, fru^P1.LexA/fru^AJ96u3 has abnormal song phenotype

(Cande et al., 2014)

dsx¹, fru^Δtra has abnormal neuroanatomy | female | adult stage phenotype

(Mellert et al., 2010)

dsx¹, ix³ has viable phenotype

(Garrett-Engele et al., 2002)

dsx[+]/dsx¹, ix³ has viable phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has viable phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx[+]/dsx¹ has viable phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has viable phenotype

(Garrett-Engele et al., 2002)

dsx¹, her¹ has abnormal sex-determination | recessive phenotype

(Li and Baker, 1998)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

dsx^Δ, fru^P1.LexA, dsx¹, Df(3R)Exel6179 is a non-suppressor of adult posterior midgut epithelium | female limited phenotype of N^KK102890, Scer\GAL4^NP7397

(Hudry et al., 2016)

Other

Statement

Reference

Df(3R)dsx3/dsx¹, Df(3R)fru^sat15 has gonad | adult stage phenotype

(Zhou et al., 2021)

dsx¹, fru^Δtra has prothoracic leg taste bristle chemosensory neuron | female phenotype

(Mellert et al., 2010)

Df(2R)en-B/ix³, dsx¹ has abdominal tergite 6 | female phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has hypogynial tooth phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has abdominal tergite 6 | female phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has hypogynial tooth phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has sex comb phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has abdominal sternite 6 phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has epiproct phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³ has prothoracic metatarsus | female phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has abdominal tergite 6 | female phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has hypogynial tooth phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has sex comb phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has abdominal sternite 6 | male phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has cercus phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has abdominal sternite 6 | male phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has epiproct phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx⁹/dsx¹ has prothoracic metatarsus phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has cercus phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/+, dsx⁹/dsx¹ has abdominal tergite 6 | female phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/+, dsx⁹/dsx¹ has hypogynial tooth phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/+, dsx⁹/dsx¹ has abdominal sternite 6 phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has epiproct phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/+, dsx⁹/dsx¹ has epiproct phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/+, dsx⁹/dsx¹ has prothoracic metatarsus | female phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³/ix[+] has abdominal tergite 6 | female phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³/ix[+] has hypogynial tooth phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³/ix[+] has abdominal sternite 6 phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³/ix[+] has epiproct phenotype

(Garrett-Engele et al., 2002)

dsx⁹/dsx¹, ix³/ix[+] has prothoracic metatarsus | female phenotype

(Garrett-Engele et al., 2002)

Df(2R)en-B/ix³, dsx¹ has prothoracic metatarsus phenotype

(Garrett-Engele et al., 2002)

dsx¹, her¹ has cercus phenotype

(Li and Baker, 1998)

dsx¹, her¹ has epiproct phenotype

(Li and Baker, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

dsx^Δ/dsx¹, Df(3R)Exel6179/+ individuals, dsx^Δ/dsx¹, Df(3R)Exel6179/fru^Δtra individuals and dsx^Δ/dsx¹, fru^P1.LexA/Df(3R)Exel6179 individuals do not show significant changes in mitotic index in the female and male adult posterior midgut, as compared to controls.

fru^P1.LexA/Df(3R)Exel6179, dsx¹/dsx^Δ double transheterozygosity does not suppress the increased mitotic index in the female adult posterior midgut induced by the adulthood-only expression of N^KK102890 under the control of Scer\GAL4^esg-NP7397 (and Gal80[ts], for the temporal regulation of expression).

(Hudry et al., 2016)

XX dsx¹ fru^Δtra/dsx¹ animals have contralateral foreleg gustatory receptor neuron (GRN) axons in most cases. These XX animals have on average, less midline crossings than their XY dsx¹ fru^Δtra/dsx¹ siblings.

(Mellert et al., 2010)

ix; dsx transheterozygous progeny from ix³/+; dsx¹/+ females crossed to Df(2R)en-B/+; dsx⁹/+ males show little or no masculinisation

of females, or feminisation of males, as judged by: Mean number of

vaginal teeth; percentage of females with fused dorsal-lateral anal

plates; percentage width of the 6th tergite that is darkly pigmented;

number of bristles in the last transverse row in the foreleg basitarsus

(note this row forms the sex comb in males); or number of bristles

on the sixth sternite.

ix³/Df(2R)en-B; dsx⁹/dsx¹ double mutants show masculinisation

of females, as judged by the following criteria:

The mean number of vaginal teeth is reduced to 6.45 +/- 2.11. 85 %

of females have fused dorsal-lateral anal plates (as wild type; note

that even those with fused plates exhibit variable degrees of partial

fusion as judged against fusion in wild-type females). The mean percentage

width of the 6th tergite that is darkly pigmented is increased to 95%

(+/- 0.4%). The number of bristles in the last transverse row in the

foreleg basitarsus is increased to: 7.25 +/- 0.54 ( this row forms

the sex comb in males).

ix³/Df(2R)en-B; dsx⁹/dsx¹ double mutant females do not

show significant reductions in the number of bristles on the sixth

sternite (20.75 +/- 1.83).

ix³/Df(2R)en-B; dsx⁹/dsx¹ double mutants show feminisation

of males, as judged by the following criteria:

An average of 6.85 (+/- 2.74) ectopic vaginal teeth form.

Fusion of dorso-lateral anal plates is seen in 80% of males.

The number of bristles in the last transverse row in the foreleg basitarsus

is decreased to 7.25 +/-0.54 (this row forms the sex comb in males).

The average number of bristles on the sixth sternite increases dramatically

from near zero to 18.2 +/- 1.58.

ix³/Df(2R)en-B; dsx⁹/dsx¹ double mutant males do not

show significant masculinisation of pigmentation of the 6th tergite,

which remains

96% (+/-3%) darkly pigmented.

ix³/Df(2R)en-B mutant females heterozygous for dsx⁹ or dsx¹

show masculinisation, as judged by the following criteria:

Mean number of vaginal teeth is reduced to 9.7 +/- 5.29. 90 % of females

have fused dorsal-lateral anal plates (as wild type; note that even

those with fused plates exhibit variable degrees of partial fusion

as judged against fusion in wild-type females). The mean percentage

width of the 6th tergite that is darkly pigmented is increased to 92%

(+/-6%). The number of bristles in the last transverse row in the foreleg

basitarsus is increased to: 6.88 +/- 0.65 (this row forms the sex comb

in males).

ix³/Df(2R)en-B mutant females transheterozygous for dsx⁹/+

or dsx¹/+ do not show significant reductions in the number of bristles

on the sixth sternite (21.1 +/-1.68)

ix³/Df(2R)en-B mutant males heterozygous for dsx⁹ or dsx¹

do not show feminisation, as judged by the following criteria:

Mean number of vaginal teeth; percentage of males with fused dorsal-lateral

anal plates; percentage width of the 6th tergite that is darkly pigmented;

number of bristles in the last transverse row in the foreleg basitarsus

(note this row forms the sex comb in males); or number of bristles

on the sixth sternite.

dsx⁹/dsx¹ mutant females heterozygous for ix³ or Df(2R)en-B

show masculinisation, as judged by the following criteria:

Mean number of vaginal teeth is reduced to 6.0 +/-3.55. 65 % of females

have fused dorsal-lateral anal plates (as wild type; note that even

those with fused plates exhibit variable degrees of partial fusion

as judged against fusion in wild-type females). The mean percentage

width of the 6th tergite that is darkly pigmented is increased to 96%

(+/-5%). The number of bristles in the last transverse row in the foreleg

basitarsus is increased to: 7.75 +/- 0.78 (this row forms the sex comb

in males). The average number of bristles on the sixth sternite is

slightly decreased to 19.5 +/- 1.91.

dsx⁹/dsx¹ mutant males heterozygous for ix³ or Df(2R)en-B

show feminisation, as judged by the following criteria:

An average of 6 (+/- 4.19) ectopic vaginal teeth form. Fusion of dorso-lateral

anal plates is seen in 70% of males. The number of bristles in the

last transverse row in the foreleg basitarsus is decreased to 7.45

+/-0.6 (this row forms the sex comb in males). The average number

of bristles on the sixth sternite increases dramatically from near

zero to 17.3 +/- 2.06.

dsx⁹/dsx¹ mutant males heterozygous for ix³ or Df(2R)en-B

do not show significant masculinisation of pigmentation of the 6th

tergite, which remains 95% (+/-4%) darkly pigmented.

(Garrett-Engele et al., 2002)

XX ; her¹/+ ; dsx¹/dsx¹ and XX ; her¹/her¹; dsx¹/+ flies have an average of 12.4 and 10.5 vaginal teeth respectively, indicating the intersexuality of these flies. XX ; her¹/her¹ ; dsx¹/dsx¹ flies have an average of 2.7 vaginal teeth. XY ; her¹/+ ; dsx¹/dsx¹ and XX ; her¹/her¹; dsx¹/+ flies have an average of 12.2 vaginal teeth. XY ; her¹/her¹ ; dsx¹/dsx¹ flies have an average of 3.8 vaginal teeth. 5% of XX ; her¹/her¹; dsx¹/dsx¹ flies have fused intersexual dorsal-lateral anal plates. 80% of XX ; her¹/+ ; dsx¹/dsx¹ and 30% of XX ; her¹/her¹; dsx¹/+ flies have fused intersexual dorsal-lateral anal plates.

(Li and Baker, 1998)

Xenogenetic Interactions

Statement

Reference

dsx¹ fru^P1.LexA/dsx^Δ fru^AJ96u3 double mutants rescued with Dana\dsx^+t21E22 and Dana\fru^+t20H8 sing like Drosophila melanogaster with both pulse and sine song elements present, mutants rescued with Dper\dsx^+t31M5 and Dper\fru^+t36N18 only sing normal-pulse song but not the sine song but still do not display any evidence of species-specific song interconversion.

(Cande et al., 2014)

Complementation and Rescue Data

Partially rescued by

dsx⁴³/dsx¹ is partially rescued by dsx^F.Hsp83

(Waterbury et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (5)

Bloomington

55775

y¹ w^*; P{UAS-Scop-dsx.M}2; dsx¹/MKRS

66713

P{neoFRT}82B dsx¹ TI{TI}fru^Δtra/TM2/T(1;3)OR60

1679

Dp(1;Y)Bar^S; dsx¹ p^p/TM3, Sb¹

99703

Dp(1;Y)Bar^S; dsx¹ p^p p53^5A-1-4/TM3, Sb¹

Kyoto

106447

Dp(1;Y)Bar^S; dsx¹ p^p/TM3, Sb¹

Notes on Origin

Discoverer

Hildreth.

Comments

Homozygous XX and XY flies have Yp1, Yp2 or Yp3 proteins in the haemolymph.

(Ota et al., 1981)

Pole cell transplantation experiments show that dsx function is not required in the germ line for the normal development of germ cells according to their chromosomal sex.

(Schupbach, 1982)

Rank order for subnormal courtship in dsx alleles is dsx¹ < dsx¹⁶ < dsx¹⁵ < dsx²³.

(Villella and Hall, 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Name Synonyms

Secondary FlyBase IDs

References (54)

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