Allele Dmel\e^s

General Information
Symbol	Dmel\e^s	Species	D. melanogaster
Name	sooty	FlyBase ID	FBal0003292
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\e

Allele class
Mutagen	spontaneous
Nature of the Allele
Allele class
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Assay mode
Carried on aberration	TM2Z (FlyBase Curators, 2006-) TM2-vBa (FlyBase Curators, 2006-) TM2-ry (FlyBase Curators, 2006-) C(3R)RM-P5 CyO-TM3-GFP (Rudolph et al., 1999) TM2-p^p (FlyBase Curators, 2006-) Dp(3;3)Cam36 (Roote, 2000.3.14, Roote, 2004.6.24) DcxF-Sse (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28) C(3R)RM-VK1 F(3R)2 Df(3R)Scr (Johnston et al., 1998) TM3-GFP (Rudolph et al., 1999) C(3R)RM-VC1 TM2-l(3)E7-3-58¹ (FlyBase Curators, 2006-) C(3R)RM-SK2 TM2-vFa (FlyBase Curators, 2006-) TM2-P{Δ2-3} (FlyBase Curators, 2006-) TM2 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) TM2-vAa (FlyBase Curators, 2006-) F(3R)4 (Bloomington Drosophila Stock Center, 1998.8.28)
Cytology
Phenotypic Data
Phenotypic Class
	viable body color defective (Brehme, 1941, ) locomotor rhythm defective \| recessive (Newby and Jackson, 1991)
Phenotype Manifest In
	embryonic/larval spiracle (Brehme, 1941)
Detailed Description
	Statement Reference RK1. Body colour: darker than wild-type but lighter than e¹. Classifiable from hatching throughout larval period by dark color of spiracle sheaths, although darkening is less than in e¹, e⁴, or e¹¹. (Brehme, 1941) Ability to incorporate beta-alanine-derived C intermediate between that of e¹ and wild type. (Jacobs and Brubaker, 1963) Ability to incorporate beta-alanine-derived C intermediate between that of e¹ and wild type. (Jacobs, 1966) Body colour: black. (Duncan and Kaufman, 1975) A large fraction of homozygotes are arrhythmic with respect to locomotor activity when kept in constant darkness at 24^oC, and the average signal-to-noise ratio is lower than wild-type. The rhythmicity is not affected by temperature. Homozygotes sometimes show abnormal synchronisation to light-dark cycles. The eclosion rhythm is normal. (Newby and Jackson, 1991)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference e^s is an enhancer of body color defective phenotype of Sk¹ (Lindsley and Zimm, 1992)
Phenotype Manifest In
Enhancer of
Statement Reference e^s is an enhancer of scutellum phenotype of Sk¹ (Lindsley and Zimm, 1992)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 322 )
Bloomington	498 e^s 449 as^hg e^s 1624 C(3L), st¹; C(3R), e^s 1847 Df(3R)dsx2D, Sb¹ e^s/TM2 6387 st¹ nac⁴ e^s/TM6 1856 dsx²⁵ Sb¹ e^s/CxD 9457 w¹¹¹⁸; Rel^E20 e^s 9458 w¹¹¹⁸; Rel^E38 e^s 1117 C(3)EN, st¹ cu¹ e^s 6178 k^D e^s/TM2, kni^ri-1
Kyoto	105940 e^s 106533 Df(3R)dsx2D, Sb¹ e^s/TM2
	More stocks available...
Notes on Origin
Discoverer	Sturtevant, 20 Sep. 1913.

Comments
	Intermediate strength allele. Most easily classified as e^s/e⁴.
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	e^s
Name Synonym	sooty
Secondary FlyBase IDs

References ( 16 )
Research paper	Rudolph et al., 1999, D. I. S. 82: 99--100 New type of CyO and TM3 green balancers. [FBrf0112022] Johnston et al., 1998, Genetics 149(1): 131--142 The homeobox gene cut interacts genetically with the homeotic genes proboscipedia and Antennapedia. [FBrf0102837] Newby and Jackson, 1991, J. Neurogenet. 7: 85--101 Drosophila ebony mutants have altered circadian activity rhythms but normal eclosion rhythms. [FBrf0054506] Lakhotia et al., 1990, Chromosoma 99: 296--305 Mutations affecting -alanine metabolism influence inducibility of the 93D puff by heat shock in Drosophila melanogaster. [FBrf0051446] Duncan and Kaufman, 1975, Genetics 80: 733--752 Cytogenetic analysis of chromosome 3 in Drosophila melanogaster: mapping of the proximal portion of the right arm. [FBrf0027527] Jacobs, 1966, Genetics 53: 777--784 Deposition of labeled beta-alanine in ebony and non-ebony Drosophila melanogaster with notes on other amino acids. [FBrf0017865] Jacobs and Brubaker, 1963, Science 139: 1282--1283 Beta-alanine utilization of ebony and non-ebony Drosophila melanogaster. [FBrf0015819] Brehme, 1941, Proc. Natl. Acad. Sci. USA 27: 254--261 The effect of adult body color mutations upon the larva of Drosophila melanogaster. [FBrf0005535] Bridges and Morgan, 1923, Publs Carnegie Instn 327: 1--251 The third-chromosome group of mutant characters of Drosophila melanogaster. [FBrf0001261]
Personal communication to FlyBase	Roote, 2004.6.24, Cam Dps. Cam Dps. [FBrf0178882] Bloomington Drosophila Stock Center, 2001.8.28, Balancer Variants. Balancer Variants. [FBrf0138610] Roote, 2000.3.14, Dp(3;3)Cam's. Dp(3;3)Cam's. [FBrf0126882] Bloomington Drosophila Stock Center, 1998.8.28, F(3R)4, l(2)22Fc[H7] and l(2)35Fb[ck1]. F(3R)4, l(2)22Fc[H7] and l(2)35Fb[ck1]. [FBrf0104712]
FlyBase analysis	FlyBase Curators, 2006-, Balancer summary information. Balancer summary information. [FBrf0189689]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905] Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Allele Dmel\es

Allele Dmel\e^s