-marked DL1 olfactory projection neurons mistarget some of their dendrites to the dorsolateral glomerulus DA41 in the anterior of the antennal lobe instead of the DL1 glomerulus in the posterior of the antennal lobe as in wild type. However, arborization of mutant axons is not obviously altered.
-marked anterodorsal and lateral projection neuron neuroblast clones in domLL05537
mutants have a very mild reduction in cell number and their dendrites do no t traget to the full set of proper glomeruli.
-marked ventral projection neuron neuroblast clones in domLL05537
mutants exhibit incomplete targeting throughout the antennal lobe.
Heterozygotes show a significant increase in double strand break (DSB) repair via homologous recombination and a corresponding decrease in DSB repair by nonhomologous end-joining compared to controls in a somatic DSB repair assay, when either whd80k17
is used as the recipient allele bearing the target break site.
The genome of E(Pc)1
/+ flies appears to be significantly more stable following exposure to irradiation (seen as induction of fewer bristles with a Minute phenotype) compared to control flies.
Heterozygous wing discs show an approximately twofold reduction in radiation-induced apoptosis compared to controls.
Heterozygotes show an increased survival rate following irradiation compared to control animals.
Mutation changes the level of w
expression in ph-plac+3
flies; eye colour is darker.
The cuticles of embryos lacking both maternal and zygotic E(Pc)
product appear wild type.
No homeotic phenotype in embryos or adults. Strong enhancers of Pc
heterozygotes are cuticularly normal as larvae and adults. E(Pc)1
is a recessive lethal mutation; homozygotes and hemizygotes die as late embryos or larvae, which appear cuticularly normal.