V663D | gro-PA; V663D | gro-PB; V663D | gro-PC; V663D | gro-PD; V674D | gro-PE; V663D | gro-PF; V672D | gro-PG; V653D | gro-PH; V642D | gro-PI; V661D | gro-PJ
Nucleotide substitution inferred from reported amino acid change. Position of mutation on reference sequence inferred by FlyBase curator.
Polytene chromosomes normal.
macrochaeta & scutum
microchaeta & scutum
sense organ & wing
gro1/groE48 adults heterozygous for sbb6 show an enlarged anterior wing compartment. Ectopic longitudinal wing vein L2 and L3 tissue develops, and transformation of the anterior wing margin bristles into more posteriorly located sensory organs is observed.
The severity of cuticle defects seen in eve1 embryos is increased if the mother is also heterozygous for groE48. The defects are pair rule in nature. The degree of rescue of the eve3 embryonic phenotype conferred by one copy of eveE+L.8.4 is reduced if the mother is heterozygous for groE48. The degree of rescue of the eve3 embryonic phenotype conferred by two copies of eveEGNΔLFK is reduced slightly if the mother is heterozygous for groE48.
Eggs from Rpd304556/groE48 mothers exhibit an embryonic lethality significantly higher than from either groE48/+ or Rpd304556/+ mothers. Cuticles from unhatched embryos show a bicaudal phenotype, including a duplicated posterior spiracle, and a mirror image duplication of the posterior abdominal segments in place of the normal anterior segments. Eggs from Df(3L)10H/groE48 mothers exhibit an embryonic lethality significantly higher than from either groE48/+ or Df(3L)10H/+ mothers. 50-60% had no cuticle. Cuticles from 5-10% of unhatched embryos show a duplication of the posterior spiracle accompanied by disorganised denticle belts.