FlyBase Allele Report: Dmel\E(w[a])[1]

General Information

Symbol

Dmel\E(w^a)¹

Species

D. melanogaster

Name

FlyBase ID

FBal0003363

Feature type

allele

Associated gene

E(w^a)

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

antimorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

antimorphic allele - genetic evidence

(Peng and Mount, 1990, Birchler and Hiebert, 1989)

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile

(Peng and Mount, 1990)

Phenotype Manifest In

Detailed Description

Statement

Reference

Males have variable fertility for an unknown reason.

(Peng and Mount, 1990)

Heterozygote dilutes w^a to pale yellow. Homozygote with w^a is white. Enhances w^a1 and w^a4. Also enhances w^sp55 and w^h (Birchler, 1986) but not w^a2, w^a3, w^bf, w^Bwx, w^cf, w^ch, w^co, w^col, w^e, or w^sp1; enhances phenotype of w^a1/w^bf. No effect on eye color in presence of w⁺; and no interaction with other eye-color mutants. Enhancement dominant to two doses of the normal allele in w^a/bw⁺Y;E(w^a)/+. homozygous male-sterile homozygous female partially fertile RK3.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

E(w^a)¹ has phenotype, non-enhanceable by w^r

(Mount et al., 1988)

E(w^a)¹ has phenotype, non-enhanceable by w^aRsLTR

(Mount et al., 1988)

Enhancer of

Statement

Reference

E(w^a)¹ is an enhancer of phenotype of w^ric

(Rabinow and Birchler, 1990)

E(w^a)¹ is an enhancer of phenotype of w^apl

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^h

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^ch2

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^aR84h

(Birchler and Hiebert, 1989, Mount et al., 1988)

E(w^a)¹ is an enhancer of phenotype of w^e2

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^e

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^a4

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^sp55

(Birchler and Hiebert, 1989)

E(w^a)¹ is an enhancer of phenotype of w^aM

(Birchler and Hiebert, 1989, Mount et al., 1988)

E(w^a)¹ is an enhancer of phenotype of w^aR79l27

(Mount et al., 1988)

E(w^a)¹ is an enhancer of phenotype of w^a79i

E(w^a)¹ is an enhancer of phenotype of w^a

NOT Enhancer of

Statement

Reference

E(w^a)¹ is a non-enhancer of phenotype of w^a3

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^is

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^sp81d

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^co

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^sat

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^Bwx

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^mo

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^col

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR6

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^ec3

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^zl

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR5

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^t

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR1

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR3

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^sp1

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^c

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^bf2

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^bl

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR2

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^zm

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^bf

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^a57i11

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of wⁱ

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^a58l

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^sp2

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^IR4

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^cf

(Birchler and Hiebert, 1989)

E(w^a)¹ is a non-enhancer of phenotype of w^a59k1

(Birchler and Hiebert, 1989, Mount et al., 1988)

E(w^a)¹ is a non-enhancer of phenotype of w^r

(Mount et al., 1988)

E(w^a)¹ is a non-enhancer of phenotype of w^aRsLTR

(Mount et al., 1988)

NOT Suppressor of

Statement

Reference

E(w^a)¹ is a non-suppressor of phenotype of w^hd81b6

(Rabinow and Birchler, 1990)

E(w^a)¹ is a non-suppressor of phenotype of w^hd81b11

(Rabinow and Birchler, 1990)

E(w^a)¹ is a non-suppressor of phenotype of w^hd81b25

(Rabinow and Birchler, 1990)

Additional Comments

Genetic Interactions

Statement

Reference

E(w^a) strongly interacts with w alleles that result from the insertion of the transposable elements copia, 3S18 and the element in w^sp55. No interaction with alleles that result from the insertion of the transposable elements FB, I-element, 3S18 and roo. An extra copy of E(w^a) ameliorates the mutant effect and the presence of three normal copies has no phenotypic consequences beyond the normal diploid.

(Birchler and Hiebert, 1989)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

106171

Dp(2;Y)bw⁺/y¹ w^a; E(w^a)¹/CyO

Notes on Origin

Discoverer

Scandlyn.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

E(w^a)¹

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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