Allele Dmel\E(w^a)¹

General Information
Symbol	Dmel\E(w^a)¹	Species	D. melanogaster
Name		FlyBase ID	FBal0003363
Feature type	allele	Associated gene	Dmel\E(w^a)

Allele class	antimorphic allele - genetic evidence
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	antimorphic allele - genetic evidence (Birchler and Hiebert, 1989, Peng and Mount, 1990)
Mutagen	spontaneous
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	female sterile (Peng and Mount, 1990)
Phenotype Manifest In

Detailed Description
	Statement Reference Males have variable fertility for an unknown reason. (Peng and Mount, 1990) Heterozygote dilutes w^a to pale yellow. Homozygote with w^a is white. Enhances w^a1 and w^a4. Also enhances w^sp55 and w^h (Birchler, 1986) but not w^a2, w^a3, w^bf, w^Bwx, w^cf, w^ch, w^co, w^col, w^e, or w^sp1; enhances phenotype of w^a1/w^bf. No effect on eye color in presence of w⁺; and no interaction with other eye-color mutants. Enhancement dominant to two doses of the normal allele in w^a/bw⁺Y;E(w^a)/+. homozygous male-sterile homozygous female partially fertile RK3.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhanced by
Statement Reference E(w^a)¹ has phenotype, non-enhanceable by w^aRsLTR (Mount et al., 1988) E(w^a)¹ has phenotype, non-enhanceable by w^r (Mount et al., 1988)
Enhancer of
Statement Reference E(w^a)¹ is an enhancer of phenotype of w^a4 (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^a79i E(w^a)¹ is an enhancer of phenotype of w^a E(w^a)¹ is an enhancer of phenotype of w^aM (Birchler and Hiebert, 1989, Mount et al., 1988) E(w^a)¹ is an enhancer of phenotype of w^apl (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^aR79l27 (Mount et al., 1988) E(w^a)¹ is an enhancer of phenotype of w^aR84h (Birchler and Hiebert, 1989, Mount et al., 1988, ) E(w^a)¹ is an enhancer of phenotype of w^ch2 (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^e2 (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^e (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^h (Birchler and Hiebert, 1989) E(w^a)¹ is an enhancer of phenotype of w^ric (Rabinow and Birchler, 1990) E(w^a)¹ is an enhancer of phenotype of w^sp55 (Birchler and Hiebert, 1989)
NOT Enhancer of
Statement Reference E(w^a)¹ is a non-enhancer of phenotype of w^a3 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^a57i11 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^a58l (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^a59k1 (Mount et al., 1988, Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^aRsLTR (Mount et al., 1988) E(w^a)¹ is a non-enhancer of phenotype of w^bf2 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^bf (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^bl (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^Bwx (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^c (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^cf (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^co (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^col (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^ec3 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of wⁱ (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR1 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR2 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR3 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR4 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR5 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^IR6 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^is (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^mo (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^r (Mount et al., 1988) E(w^a)¹ is a non-enhancer of phenotype of w^sat (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^sp1 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^sp2 (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^sp81d (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^t (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^zl (Birchler and Hiebert, 1989) E(w^a)¹ is a non-enhancer of phenotype of w^zm (Birchler and Hiebert, 1989)
NOT Suppressor of
Statement Reference E(w^a)¹ is a non-suppressor of phenotype of w^hd81b6 (Rabinow and Birchler, 1990) E(w^a)¹ is a non-suppressor of phenotype of w^hd81b11 (Rabinow and Birchler, 1990) E(w^a)¹ is a non-suppressor of phenotype of w^hd81b25 (Rabinow and Birchler, 1990)
Additional Comments
Genetic Interactions
Statement Reference E(w^a) strongly interacts with w alleles that result from the insertion of the transposable elements copia, 3S18 and the element in w^sp55. No interaction with alleles that result from the insertion of the transposable elements FB, I-element, 3S18 and roo. An extra copy of E(w^a) ameliorates the mutant effect and the presence of three normal copies has no phenotypic consequences beyond the normal diploid. (Birchler and Hiebert, 1989)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	1024 Dp(2;Y)bw⁺/y¹ w^a; E(w^a)¹/CyO
Kyoto	106171 Dp(2;Y)bw⁺/y¹ w^a; E(w^a)¹/CyO
Notes on Origin
Discoverer	Scandlyn.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	E(w^a)¹ unnamed (Mount et al., 1988)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Peng and Mount, 1990, Genetics 126: 1061--1069 Characterization of enhancer-of-white-apricot in Drosophila melanogaster. [FBrf0051917] Rabinow and Birchler, 1990, Genet. Res. (Camb.) 55: 141--151 Interactions among modifiers of retrotransposon-induced alleles of the white locus of Drosophila melanogaster. [FBrf0051869] Birchler and Hiebert, 1989, Genetics 122: 129--138 Interaction of the Enhancer of white-apricot with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049880] Mount et al., 1988, Genetics 118: 221--234 Partial revertants of the transposable element-associated suppressible allele white-apricot in Drosophila melanogaster: Structures and responsiveness to genetic modifiers. [FBrf0048200]
Thesis	Reed, 1992, Ph.D. Thesis, University of Cambridge, England: 292pp The genetic analysis of endoreduplication in Drosophila melanogaster. [FBrf0064297]

Allele Dmel\E(wa)1

Allele Dmel\E(w^a)¹