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General Information
Symbol
Dmel\exd2
Species
D. melanogaster
Name
FlyBase ID
FBal0003911
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
exdYO12, exdY012
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C15994108T

Amino acid change:

Q137term | exd-PA; Q137term | exd-PB; Q137term | exd-PD; Q137term | exd-PE

Reported amino acid change:

?137term

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: C615T.

Amino acid replacement: ?137term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones in the lateral region of the notum contain several macrochaetae that are not normally present in this region. Large homozygous clones induced using the Minute technique show alterations of the bristle pattern in the scutellum and the disappearance of the suture between the scutum and the scutellum.

Embryos lack both maternal and zygotic exd.

Most segments are altered in hemizygous embryos. The H piece is often severely disrupted. Ventrally, T1 is normal, T2 is partially transformed to T1, T3 has some of the characteristics of both T1 and A2, Keilin's organs and ventral pits are unchanged, A1-A5 are transformed more posteriorly, assuming the morphology of the segment two or three segments posterior, and A6-A8 are normal or near normal. Anterior and posterior terminal structures are normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Heterozygotes enhance the lethality of a Dfd3/Dfd13 transheterozygote combination.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
References (12)