FlyBase Allele Report: Dmel\ey[1]

General Information

Symbol

Dmel\ey¹

Species

D. melanogaster

Name

FlyBase ID

FBal0003920

Feature type

allele

Associated gene

Dmel\ey

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Hughes and Shelton, 1980)

visible | heat sensitive

Phenotype Manifest In

adult optic lobe

(Richards and Furrow, 1922)

adult subretinal glial cell

(Hummel et al., 2002)

eye

(Hughes and Shelton, 1980)

eye | heat sensitive

eye disc

(Kumar and Moses, 2001)

lamina anlage glial cell

(Hummel et al., 2002)

photoreceptor neuron

(Kumar and Moses, 2001)

Detailed Description

Statement

Reference

Homozygous mutant larvae exhibit an early onset glial cell migration defect in the developing eye.

(Hummel et al., 2002)

Despite the lack of photoreceptors, the eye disc is still present (in reduced form) in homozygous mutants.

(Kumar and Moses, 2001)

Displays locomotor activity rhythm with an approximately 24h period.

(Vosshall and Young, 1995)

Optic ganglia reduced.

(Richards and Furrow, 1922)

Eye size relative to that of wild type: .50-.75 Eye reduced to three-fourths to one-half normal area but varies from no eyes to extensive overlapping of wild type. Less extreme at low temperatures. RK2.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ey¹ has visible phenotype, suppressible | partially by Mpe¹

(Hughes and Shelton, 1980)

Other

Statement

Reference

ey¹, eyg¹ has lethal phenotype

(Hunt, 1970)

Phenotype Manifest In

Enhanced by

Statement

Reference

ey¹ has photoreceptor neuron phenotype, enhanceable by gish¹

(Hummel et al., 2002)

Suppressed by

Statement

Reference

ey¹ has eye phenotype, suppressible | partially by Mpe¹

(Hughes and Shelton, 1980)

NOT suppressed by

Statement

Reference

ey¹ has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Enhancer of

Statement

Reference

ey¹ is an enhancer of photoreceptor neuron phenotype of gish¹

(Hummel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

647

ey¹

Kyoto

106025

ey¹

Notes on Origin

Discoverer

Hoge, May 1914.

Comments

Variability in size of eye affected by environmental and genetic conditions.

(Baron, 1935, Morgan, 1929)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

(Hughes and Shelton, 1980)

ey¹

(Yoshioka et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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