G523S | fliI-PA
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Amino acid replacement: G523S.
flightless (with fliIsdby)
flightless | recessive
indirect flight muscle
presumptive embryonic/larval central nervous system
presumptive embryonic/larval peripheral nervous system
Hemizygotes have normal viability. fliI5/Df(1)18-80, fliI5/fliI14, fliI5/fliI10 and fliI5/fliI21 flies are flightless.
Homozygous viable. Homozygous germline clones display no maternal effect. Embryos derived from heterozygous mothers have CNS and PNS defects.
Indirect flight muscles have abnormal arrangement of myofibrils and distorted Z bands. fliI5/fliI8 flies are flightless.
fliIsdby/fliI5 flies hold their wings normally but are completely flightless.
Mosaic analysis with suggests primary defect in thoracic muscles.