disrupted planar polarity is observable as the disrupted orientation of ommatidia, compared to wild type controls.
transheterozygous adults show hair polarity defects in abdominal bristles.
Mutant adults have an average of 2.9 +/- 0.6 extra tarsal joints in the leg compared to wild type.
The orientation of trichomes is uniformly randomised only in the most central region of the notum in mutant animals.
Homozygous clones in the notum nonautonomously influence the polarity of neighbouring bristles and trichomes.
mutant wings display strong hair orientation defects, but very few if any multiple hairs.
stage 16 embryos have longer dorsal trunks than normal.
In contrast to wild-types, no clear wing membrane ridge orientation is apparent in either the anterior or posterior region of the wing of fz23
Prehair initiation is delayed in mutant cells away from the clone edge in homozygous clones in the wing.
Approximately 16% of ommatidia are symmetrical in fz19
The wing hairs in fz21
mutants no longer point uniformly from proximal to distal as is seen in wild type.
clones in the pupal wing (32 hours after puparium formation) cause neighbouring cells to point their trichomes towards the clone.
Most larvae from fz15
mothers crossed with fz15
/+ fathers have cuticles with normal morphology; only 2 of 30 exhibit fusions between segments. Another 2 mutants exhibit misplaced actin-based protrusions in denticle row 1.
The hexagonal packing of intervein cells, which usually occurs between wing development stage P2B (when the first morphological signs of veins appear (FBrf0005070
), and the middle of P2C (before hair formation (FBrf0005070
)) is partially disrupted in fz21
Mutant clones in the wing result in domineering nonautonomy wing hair polarity phenotype.
Somatic clones in the wing disc do not exhibit significant delay in hair development.
ovaries show only very minor abnormalities.
Mutant clones in the wing show domineering non-autonomy: cells distal to the clone, as well as within the clone, show alteration of polarity of wing hairs.
Homozygous somatic clones in the wing cause domineering non-autonomy.
Dendritic development in fz21
mutants is indistinguishable from wild-type.
Non-autonomous phenotype in wing clones.
Moderate thoracic bristle phenotype; moderate wing-hair disorientation.