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General Information
Symbol
Dmel\g1
Species
D. melanogaster
Name
FlyBase ID
FBal0004957
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
garnet1
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

4kb insertion in g.

Insertion components
?{}g1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant flies show a reduction in survival on a glycerol only food source compared to control flies.

Mutant flies show some decrease in ommochrome pigment levels and a significant reduction in drosopterin pigment levels compared to wild type.

Mutant males have a shortened adult life span compared to controls, with a mean life span of 27.41 days at 25o.

g1 mutant females have 57% red pigment in the eye compared to 100% in wild-type flies. g1/Df(1)HA92 mutants have lower levels of red eye pigment than g1 homozygous mutants. g1 mutant male flies show a greater degree of male-male courtship than wild-type flies.

Eye colour: the drosopterin (red pigment) content of g1 flies is reduced compared to wild type. Eye colour: the drosopterin (red pigment) content of g1 rb1 double mutant flies is reduced to 18% of wild type. Eye colour: the xanthommatin (brown pigment) content of g1 flies is reduced to 58% of wild type. Eye colour: the xanthommatin (brown pigment) content of g1 rb1 double mutant flies is reduced to 41% of wild type. Mutant flies show disturbed orientation behaviour and walking speed in a behavioural assay.

Eye colour: red pigments are reduced to 57 +/- 2% of wild-type levels, brown pigments are reduced to 25 +/- 3% of wild-type levels in females. Red pigments are reduced to 72 +/- 4% of wild-type levels, brown pigments are reduced to 66 +/- 1% of wild-type levels in males. Malpighian tubule colour: colourless (wild-type colour is orange). Testis colour: pale yellow (wild-type colour is bright yellow).

Lightly pigmented eyes and some pigment deposition in the ocelli.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

g1 has eye color defective phenotype, enhanceable by we(g)

Df(1)HA92/g1 has eye color defective phenotype, enhanceable by w[+]/we(g)

g1 has eye color defective phenotype, enhanceable by Df(1)N-8/+

g1 has eye color defective phenotype, enhanceable by Df(1)N-8/we(g)

Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

Df(1)HA92/g1 has pigment cell phenotype, enhanceable by w[+]/we(g)

g1 has pigment cell phenotype, enhanceable by Df(1)N-8/+

g1 has pigment cell phenotype, enhanceable by Df(1)N-8/we(g)

g1 has pigment cell phenotype, enhanceable by we(g)/we(g)

g1 has phenotype, enhanceable by we(g)

NOT Enhancer of
Statement
Reference
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The glycerol hypersensitivity of flies expressing GykdsRNA.Scer\UAS under the control of Scer\GAL4c564 (seen as a reduction in survival on a glycerol only food source) is enhanced if the flies are also heterozygous for g1.

The reduction in drosopterin pigment levels seen in flies carrying wdsRNA.GMR is enhanced manyfold if they are also mutant for g1.

The reduction in the number of dendritic endpoints of dorsal dendritic arborisation neurons which is seen in larvae expressing NakdsRNA.Scer\UAS under the control of Scer\GAL4109(2)80 is not enhanced by g1/+.

g1 is a complex modifier of the eye phenotype caused by expression of bchsEP2299 under the control of Scer\GAL4GMR.PF.

The level of pteridine eye pigments in g1 ; ltd1 double mutant flies are significantly lower than that of the corresponding single mutants.

g1, we(g) double mutant flies have significantly lower levels of red pigment in their eyes than g1 single mutants. Likewise, Df(1)HA92/g1, we(g)/+ mutants have lower levels of red pigment in the eye than Df(1)HA92/g1 single mutants. Further, g1, Df(1)N-8/+ double mutant flies have less red pigment in their eyes than the g1, we(g) double mutants, while g1, Df(1)N-8/we(g) flies have the least pigment of the mutant combinations described here.

Eye colour: nearly white, with ltd1. Pale eye color due to the absence of pteridines and brown pigment.

Eye colour: cho1 g1 eye colour is indistinguishable from g1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (2)
Stocks (13)
Notes on Origin
Discoverer

Bridges, 19th Feb. 1915.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (23)