The chromosome containing the gro mutation contains two inserts, one of about 4 kb between coordinates -4.8 and -3.8 kb and a much smaller one at approximately +11.5 detected by Preiss et al. The larger of the two is independent of the gro mutation since Df(3R)Pr4, which deletes the region into which the segment is inserted, does not uncover gro; a similar argument for the independence of the insert at 11.5 can be made since gro is rescued by transformation with a segment from 12.7 to 23.1 (Preiss et al.).
adult head & microchaeta
macrochaeta & abdominal tergite
macrochaeta & head
macrochaeta & thorax
microchaeta & abdominal tergite
microchaeta & head
microchaeta & thorax
gro1/groE48 adults heterozygous for sbb6 show an enlarged anterior wing compartment. Ectopic longitudinal wing vein L2 and L3 tissue develops, and transformation of the anterior wing margin bristles into more posteriorly located sensory organs is observed.
Egfrt1 enhances the bristle, ocellar, wing and limb phenotypes of homozygotes. Bristle hyperplasia, ocellus enlargement and ocellus fusion are enhanced. Wings are notched, wing margins are hairier, have ectopic vein material and anterior outgrowths. Legs are fused and bifurcated. Egfrf1; gro1/gro1 and Egfrf13; gro1/gro1 flies display an enhanced gro phenotype: ectopic compound eyes, fused or bifurcated legs. These phenotypes are almost exclusively restricted to males. The ectopic eyes are organised into arrays of ommatidia. They are frequently adjacent to the endogenous eye but separated by a discrete border and exhibit defects in ommatidial packing and the distribution of interommatidial bristles. Egfrt1/Df(2R)Egfr18; gro1/gro1 flies display a combination of Egfr and gro phenotypes. The L4 wing vein defect is restored and the ocellar bristles are present but disarrayed. In many cases supernumerary ocellar bristles and/or interocellar bristles are present producing a patch of bristles were the ocelli would normally have been. The ocelli are either reduced or eliminated. Most males display one or more ectopic eye structure dorso-medial to the normal eyes. These structures are small and contain discrete ommatidia but no interommatidial bristles. The lens material of these ectopic eyes is fused into a uniform glaze and they are recessed into the head cuticle.