Allele Dmel\hb¹

General Information
Symbol	Dmel\hb¹	Species	D. melanogaster
Name		FlyBase ID	FBal0005392
Feature type	allele	Associated gene	Dmel\hb
Also Known As	hb^IIU

Map ( GBrowse )
Allele class	hypomorphic allele - genetic evidence
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Hulskamp et al., 1994, )
Mutagen	ethyl methanesulfonate (Tearle and Nusslein-Volhard, 1987, Lehmann and Nusslein-Volhard, 1987, Hulskamp et al., 1994)
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 3R:4,518,055..4,518,055 reported_na_change=C?T evidence=experimental na_change=C4518055T pr_change=Q608\|hb-PA,Q608\|hb-PB reported_pr_change=Q608@ (Hulskamp et al., 1994)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: Q608@. Nucleotide substitution: CAA to TAA. Q608 lies within the second zinc finger domain. (Hulskamp et al., 1994)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage \| gap \| recessive
Phenotype Manifest In
	embryonic mesothoracic segment (Hulskamp et al., 1994) embryonic metathoracic segment (Hulskamp et al., 1994)
Detailed Description
	Statement Reference The second and third thoracic segments are missing. (Hulskamp et al., 1994) Lacks mesothoracic and metathoracic segment and the denticle band of the eighth abdominal segment. (Lehmann and Nusslein-Volhard, 1987) Retains prothoracic, labial and A7 segments.
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 7 )
Bloomington	6385 wg^Sp-1/CyO, P{ftz/lacC}USC1; Ki¹ hb¹ ry¹/TM3, Sb¹ 6259 wg^Sp-1/CyO; Ki¹ hb¹ ry¹/TM3, P{ftz/lacC}SC1, Sb¹ ry^RK
Kyoto	108973 wg^Sp-1/CyO, P{ftz/lacC}USC1; Ki¹ hb¹ ry¹/TM3, Sb¹ 108971 wg^Sp-1/CyO; Ki¹ hb¹ ry¹/TM3, P{ftz/lacC}SC1, Sb¹ ry^RK 101951 CyO / wg^Sp-1 ; Ki¹ hb¹ ry¹ / TM3, kni^ri-1 p^p ry¹ Sb¹ P{ftz/lacC} 101953 CyO, Cy¹ dp^lv1 pr¹ cn² P{ftz/lacC}USC1 / wg^Sp-1 ; Ki¹ hb¹ ry¹ / TM3, Sb¹ 101739 ru¹ h¹ th¹ st¹ hb¹ / TM3, y⁺ kni^ri-1 p^p vvl^sep Sb¹ Ubx^bx-34e e^s Ser¹
Notes on Origin
Discoverer

Comments
	Weak hb allele: phenotypic class III. (Lehmann and Nusslein-Volhard, 1987) Class III allele.
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	hb¹ hb^IIU (Hulskamp et al., 1994, Lehmann and Nusslein-Volhard, 1987, Tearle and Nusslein-Volhard, 1987, Riede, 2004)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Riede, 2004, D. I. S. 87: 54--59 Switch genes in tumor formation. [FBrf0186405] Colas et al., 1995, Proc. Natl. Acad. Sci. U.S.A. 92(12): 5441--5445 Drosophila 5-HT₂ serotonin receptor: coexpression with fushi-tarazu during segmentation. [FBrf0081644] Hulskamp et al., 1994, Genetics 138(1): 125--134 Differential regulation of target genes by different alleles of the segmentation gene hunchback in Drosophila. [FBrf0076537] Lehmann and Nusslein-Volhard, 1987, Dev. Biol. 119: 402--417 hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo. [FBrf0046026] Nusslein-Volhard and Wieschaus, 1980, Nature 287(5785): 795--801 Mutations affecting segment number and polarity in Drosophila. [FBrf0035438]
Stock list	Tearle and Nusslein-Volhard, 1987, D. I. S. 66: 209--269 Tubingen mutants and stock list. [FBrf0045941]

Allele Dmel\hb1

Allele Dmel\hb¹