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General Information
Symbol
Dmel\hb6
Species
D. melanogaster
Name
FlyBase ID
FBal0005397
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hb9K49
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G8693034A

Reported nucleotide change:

G?A

Amino acid change:

R374H | hb-PA; R374H | hb-PB

Reported amino acid change:

R374H

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: R374H. Nucleotide substitution: CGT to CAT. R374 lies behind the first zinc finger domain in the C box.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes display duplication of abdominal segment 1 at the cuticle level.

Homozygotes have a prothorax and 9 abdominal segments.

hb6/hb6 embryos lack meso- and metathorax, but nine abdominal segments are formed, the most anterior being T2 transformed into A1 and the next the normal A1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Class V allele.

Phenotypic class Va hb allele.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)