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General Information
Symbol
Dmel\hh3
Species
D. melanogaster
Name
FlyBase ID
FBal0005464
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hh6N16, hh6N
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In hh3 mutants, midline cells do not differentiate and instead die during late embryogenesis.

Mutant embryos have exclusively row-5-type denticles arranged in a disorganized pattern of ventral midline whorls, with no naked cuticle.

40% length of wild type larvae and exhibit a ventral lawn of denticles associated with the loss of naked cuticle from the ventral surface. No obvious segmentation.

Deletion of naked cuticle and fusion of denticle bands.

Strong phenotype. Mutant embryos show no obvious segmentation, and are 40% the length of wild type; denticles form a lawn arranged in a number of whorls on the ventral surface as a result of loss of naked cuticle.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhancer of
Statement
Reference

hh3 is a non-enhancer of eye phenotype of Nspl-1

Additional Comments
Genetic Interactions
Statement
Reference

Has no effect on the eye phenotype of Nspl-1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Allelic series in terms of phenotype severity: hh3 > hh8 > hh4.

Strong allele of hh.

Mutations in hh enhance the wg phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (13)