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General Information
Symbol
Dmel\kni10
Species
D. melanogaster
Name
FlyBase ID
FBal0005780
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
kniIID48, kniIID, kni2D48
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

hb, kni double mutants show reduced rate of germ band extension. Cell intercalation is reduced in the region where the germ band fails to narrow, i.e. the region where eve and other pair-rule gene expression is uniform.

kni10 hb4 double mutant embryos fail to undergo normal germ band extension.

Premature reduction of gt protein in the posterior domain. In the head region the middle stripe persists as an unbroken band covering the entire ventral side.

Interacts with RpII140wimp maternal effect.

Posterior gt expression domain fails to narrow completely to a stripe during cellularization.

strong

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Anterior-posterior polarization of cells in the extending germband is disrupted in kni10 hb4 fkh1 tll1 homozygous embryos.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
References (26)