Allele Dmel\L2
| General Information | |||
|---|---|---|---|
| Symbol | Dmel\L2 | Species | D. melanogaster |
| Name | FlyBase ID | FBal0005882 | |
| Feature type | allele | Created / Updated | 2006-08-22/2006-08-22 |
| Associated gene | Dmel\L | ||
| Allele class | neomorph | ||
| Mutagen | spontaneous | ||
Nature of the Allele
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| Allele class | |||
| Mutagen | |||
| Mapped Features and Mutations | |||
Type Symbol & Location Additional Notes References | |||
| Associated Sequence Data | |||
| DDBJ
/
EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Progenitor genotype | |||
| Nature of the lesion | Statement Reference | ||
| Assay mode | |||
| Cytology | |||
Phenotypic Data
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Phenotypic Class
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lethal (with Df(2R)trix) | |||
Phenotype Manifest In
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Detailed Description
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Statement Reference Eyes of L2/+ as small as or smaller than L1/L1. L2 homozygotes have tiny eyes and are poorly viable or completely lethal, depending on background. L2 flies do not differ from wild type in speed of development. Heterozygotes have a nick near the anterior midline of the eye and the overall size of the eye is reduced. Heterozygotes show loss of almost all ventral ommatidia; apart from a few cells along the ventral eye margin, nearly all ommatidia in L2/+ flies are dorsal in fate. This loss of ventral eye pattern is also seen in heterozygous eye discs. | |||
Interactions
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Phenotypic Class
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Enhanced by | |||
Statement Reference | |||
NOT Enhanced by | |||
Statement Reference L2 has cell death increase | larval stage | dominant phenotype, non-enhanceable by p53Scer\UAS.Ex/Scer\GAL4ey.PH | |||
Suppressed by | |||
Statement Reference L2 has visible | dominant phenotype, suppressible | conditional ts by ushScer\UAS.cFa/Scer\GAL4ey.PH L2 has visible | dominant phenotype, suppressible | partially by mir-278EP1229/Scer\GAL4ey.PH/EP1229EP1229 L2 has cell death increase | larval stage | dominant phenotype, suppressible | partially by thScer\UAS.cLa/Scer\GAL4ey.PH L2 has cell death increase | larval stage | dominant phenotype, suppressible | partially by Df(3L)H99/+ L2 has cell death increase | larval stage | dominant phenotype, suppressible | partially by Scer\GAL4ey.PH/BacA\p35Scer\UAS.cHa | |||
NOT suppressed by | |||
Statement Reference L2 has cell death increase | larval stage | dominant phenotype, non-suppressible by p53259H.GUS/Scer\GAL4ey.PH | |||
Enhancer of | |||
Statement Reference | |||
Other | |||
Statement Reference | |||
Phenotype Manifest In
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Enhanced by | |||
Statement Reference | |||
NOT Enhanced by | |||
Statement Reference | |||
Suppressed by | |||
Statement Reference L2 has eye | ventral phenotype, suppressible | partially by mir-278EP1229/Scer\GAL4ey.PH/EP1229EP1229 L2 has eye disc | ventral phenotype, suppressible | partially by Scer\GAL4ey.PH/BacA\p35Scer\UAS.cHa | |||
NOT suppressed by | |||
Statement Reference | |||
Enhancer of | |||
Statement Reference | |||
Nature of the Allele