Allele Dmel\sesB^9Ed-6

General Information
Symbol	Dmel\sesB^9Ed-6	Species	D. melanogaster
Name		FlyBase ID	FBal0007355
Feature type	allele	Associated gene	Dmel\sesB

Map ( GBrowse )
Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Perrimon et al., 1984)
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation X:10,676,295..10,676,295 reported_na_change=G?A evidence=experimental pr_change=W125\|sesB-PC,W112\|sesB-PA,W125\|sesB-PD,W112 \|sesB-PB reported_pr_change=?112@ na_change=G10676295A (Zhang et al., 1999)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Nucleotide substitution: G?A. Amino acid replacement: ?112@. (Zhang et al., 1999)
Caused by aberration	In(1)sesB^9Ed-6 (Janca et al., 1986)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| female \| recessive (Zhang et al., 1999) lethal \| larval stage \| recessive (Perrimon et al., 1989) lethal \| male (Zhang et al., 1999) lethal \| maternal effect (Perrimon et al., 1984) partially lethal - majority die (with sesB^org) (Rikhy et al., 2003)
Phenotype Manifest In
	egg chamber \| germline clone \| maternal effect (Perrimon et al., 1984) ovariole \| germline clone (Perrimon et al., 1989)
Detailed Description
	Statement Reference 1.2% of the expected number of sesB^9Ed-6/sesB^org flies survive to adulthood. (Rikhy et al., 2003) Hemizygous male and female lethal. (Zhang et al., 1999) Homozygous sesB^9Ed-6 germline have abnormal egg chambers. (Perrimon et al., 1984) L1/L2 larval lethal abnormal oogenesis
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	sesB³ (Janca et al., 1986) sesB^9Ed-1 (Janca et al., 1986) sesB^9Ed-2 (Janca et al., 1986) sesB^9Ed-3 (Janca et al., 1986) sesB^9Ed-4 (Janca et al., 1986) sesB^9Ed-5 (Janca et al., 1986)
Rescued by	sesB^9Ed-6 is rescued by sesB^+t10.3 (Zhang et al., 1999)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Lefevre. Lefevre.

Comments
	Maternal germline clonal analysis demonstrates abnormal oogenesis, dumpless phenotype. (Perrimon et al., 1989)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	DC701 (Perrimon et al., 1989) l(1)9Ed⁶ l(1)DC701 (Zhang et al., 1998, ) l(1)EM31 (Janca et al., 1986, ) sesB^9Ed6 (Rikhy et al., 2003) sesB^9Ed-6
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Rikhy et al., 2003, Genetics 165(3): 1243--1253 A temperature-sensitive allele of Drosophila sesB reveals acute functions for the mitochondrial adenine nucleotide translocase in synaptic transmission and dynamin regulation. [FBrf0167630] Zhang et al., 1999, Genetics 153(2): 891--903 stress sensitive B encodes an Adenine Nucleotide Translocase in Drosophila melanogaster. [FBrf0111529] Perrimon et al., 1989, Genetics 121: 333--352 Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. [FBrf0049894] Janca et al., 1986, Genetics 112: 43--64 Heterogeneity of lethals in a 'simple' lethal complementation group. [FBrf0044450] Perrimon et al., 1984, Dev. Biol. 105: 404--414 The effects of zygotic lethal mutations on female germ-line functions in Drosophila. [FBrf0040730]
Abstract	Zhang et al., 1998, A. Dros. Res. Conf. 39: 565A stress sensitive B encodes the Drosophila ADP/ATP translocase. [FBrf0101602] Zhang et al., 1997, A. Dros. Res. Conf. 38: 205A sesB encodes an ADP/ATP translocase. [FBrf0092189]

Allele Dmel\sesB9Ed-6

Allele Dmel\sesB^9Ed-6