Allele Dmel\bun⁰⁰²⁵⁵

General Information
Symbol	Dmel\bun⁰⁰²⁵⁵	Species	D. melanogaster
Name		FlyBase ID	FBal0007946
Feature type	allele	Associated gene	Dmel\bun
Also Known As	l(2)00255, 00255

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{PZ}bun⁰⁰²⁵⁵ (BDGP Project Members, 1994-1999, Russell et al., 1998, Spradling et al., 1999)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage \| partially \| rescuable maternal effect (Perrimon et al., 1996) lethal \| larval stage \| recessive (Perrimon et al., 1996, Russell et al., 1998) lethal \| recessive (Spradling et al., 1999)
Phenotype Manifest In
	embryonic/first instar larval cuticle (Perrimon et al., 1996) embryonic segment (Russell et al., 1998) segment (Perrimon et al., 1996)
Detailed Description
	Statement Reference Homozygotes die during the first and second larval instar stages. Embryos derived from homozygous female germ line clones show variable segmentation defects, which can be partially paternally rescued. (Russell et al., 1998) Germline clones produce eggs with patterning defects: variable segmentation defects. (Perrimon et al., 1996)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference bun[+]/bun⁰⁰²⁵⁵ is an enhancer of visible phenotype of os¹ (Mukherjee et al., 2006)
Suppressor of
Statement Reference bun[+]/bun⁰⁰²⁵⁵ is a suppressor of visible phenotype of os^GMR.PB (Mukherjee et al., 2006)
Phenotype Manifest In
Enhancer of
Statement Reference bun[+]/bun⁰⁰²⁵⁵ is an enhancer of eye phenotype of os¹ (Mukherjee et al., 2006)
Suppressor of
Statement Reference bun[+]/bun⁰⁰²⁵⁵ is a suppressor of eye phenotype of os^GMR.PB (Mukherjee et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	bun⁰¹⁵⁵⁰ (BDGP Project Members, 1994-1999) bun⁰²⁶⁸⁷ (BDGP Project Members, 1994-1999) bun⁰³⁵⁰⁴ (BDGP Project Members, 1994-1999) bun⁰⁴²³⁰ (BDGP Project Members, 1994-1999) bun⁰⁵⁴⁷⁹ (BDGP Project Members, 1994-1999) bun⁰⁶⁴⁷⁵ (BDGP Project Members, 1994-1999) bun⁰⁶⁹⁰³ (BDGP Project Members, 1994-1999) bun⁰⁷²⁰⁹ (BDGP Project Members, 1994-1999) bun⁰⁷⁶⁹² (BDGP Project Members, 1994-1999) bun^k00612 (BDGP Project Members, 1994-1999) bun^k02603 (BDGP Project Members, 1994-1999) bun^k02903a (BDGP Project Members, 1994-1999) bun^k06713 (BDGP Project Members, 1994-1999) bun^k08813 (BDGP Project Members, 1994-1999) bun^k09018 (BDGP Project Members, 1994-1999) bun^k09036 (BDGP Project Members, 1994-1999) bun^k10318 (BDGP Project Members, 1994-1999) bun^k14715 (BDGP Project Members, 1994-1999) bun^k16604 (BDGP Project Members, 1994-1999) bun^rH541 (BDGP Project Members, 1994-1999) bun^rI482 (BDGP Project Members, 1994-1999) bun^rK499 (BDGP Project Members, 1994-1999)
Comments
Stocks ( 1 )
Bloomington	10936 P{PZ}bun⁰⁰²⁵⁵ cn¹/CyO; ry⁵⁰⁶
Notes on Origin
Discoverer	A. Spradling.

Comments
	Complements: l(2)36Ba⁰¹⁴³³. Complements: Rab6⁰⁸³²³. Complements: Elf^k06909. (BDGP Project Members, 1994-1999)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	00255 (Mukherjee et al., 2006, Gluderer et al., 2008) bun⁰⁰²⁵⁵ (Neuman-Silberberg, 2007, Christensen et al., 2008.4.15) l(2)00255 (Spradling et al., 1999, Russell et al., 1998) l(2)00255⁰⁰²⁵⁵
Name Synonym
Secondary FlyBase IDs

References ( 10 )
Research paper	Gluderer et al., 2008, BMC Dev. Biol. 8: 10 Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth. [FBrf0205279] Neuman-Silberberg, 2007, genesis 45(6): 369--381 Drosophila female sterile mutation spoonbill interferes with multiple pathways in oogenesis. [FBrf0201515] Mukherjee et al., 2006, Genetics 172(3): 1683--1697 Identification of Drosophila genes modulating janus kinase/signal transducer and activator of transcription signal transduction. [FBrf0190752] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Russell et al., 1998, Genome 41(1): 7--13 Lethal P-lacZ insertion lines expressed during pattern respecification in the imaginal discs of Drosophila. [FBrf0102000] Perrimon et al., 1996, Genetics 144(4): 1681--1692 Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. [FBrf0091142]
Personal communication to FlyBase	Christensen et al., 2008.4.15, Isolation and characterization of Df(2L)BSC407. Isolation and characterization of Df(2L)BSC407. [FBrf0204504] Beaton, 1999.12.12, Alleles of the lines in the P-element paper. Alleles of the lines in the P-element paper. [FBrf0125032] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]

Allele Dmel\bun00255

Allele Dmel\bun⁰⁰²⁵⁵