Allele Dmel\Fkbp13⁰⁰⁷³⁴

General Information
Symbol	Dmel\Fkbp13⁰⁰⁷³⁴	Species	D. melanogaster
Name		FlyBase ID	FBal0007956
Feature type	allele	Associated gene	Dmel\Fkbp13
Also Known As	l(2)00734, l(2)00734⁰⁰⁷³⁴

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:17,384,396..17,384,721 (BDGP Project Members, 1994-1999, Fox and Zinn, 2005, Spradling et al., 1999, Beaton, 2000.1.31)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{PZ}Fkbp13⁰⁰⁷³⁴ (BDGP Project Members, 1994-1999, Fox and Zinn, 2005, Spradling et al., 1999, Beaton, 2000.1.31)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (BDGP Project Members, 1994-1999, Beaton, 2000.1.31, Spradling et al., 1999)
Phenotype Manifest In

Detailed Description
	Statement Reference Fkbp13⁰⁰⁷³⁴ mutants display ISNb bypass at a similar rate to wild-type embryos. (Fox and Zinn, 2005)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
NOT Enhancer of
Statement Reference Fkbp13⁰⁰⁷³⁴ is a non-enhancer of anterior fascicle & axon \| ectopic phenotype of Lar^bypass (Fox and Zinn, 2005)
Additional Comments
Genetic Interactions
Statement Reference The Fkbp13⁰⁰⁷³⁴ mutation does not increase the frequency of the Lar^bypass ISNb bypass phenotype. (Fox and Zinn, 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	10962 cn¹ P{PZ}Fkbp13⁰⁰⁷³⁴/CyO; ry⁵⁰⁶
Notes on Origin
Discoverer	A. Spradling.

Comments
	Reversion analysis proved that the P{PZ} is responsible for the lethal phenotype. (Beaton, 2000.1.31) Complements: MESK2⁰¹⁴⁶⁷. Complements: l(2)03605⁰³⁶⁰⁵. Complements: MESK2⁰⁸⁸²⁷. Complements: MESK2⁰⁸⁸⁸². Complements: Sdc¹⁰⁶⁰⁸. Complements: l(2)k10317^k10317. (BDGP Project Members, 1994-1999)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Fkbp13⁰⁰⁷³⁴ fkbp13^M34 (Fox and Zinn, 2005) FKBP13^PZ00734 (Bokel et al., 2006) l(2)00734 (Johnson et al., 2004, Spradling et al., 1999) l(2)00734⁰⁰⁷³⁴ (Meister and Braun, 1995.10, BDGP Project Members, 1994-1999, )
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Johnson et al., 2004, Curr. Biol. 14(6): 499--504 Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance. [FBrf0174485] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Supplementary material	Bokel et al., 2006, Science 314(5802): Supporting online material. [FBrf0200011] Fox and Zinn, 2005, Curr. Biol. 15(19): Supplemental data. [FBrf0191745]
Personal communication to FlyBase	Beaton, 2000.1.31, BDGP P element Update. BDGP P element Update. [FBrf0126832] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]

Allele Dmel\Fkbp1300734

Allele Dmel\Fkbp13⁰⁰⁷³⁴