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General Information
Symbol
Dmel\Nipped-B02047
Species
D. melanogaster
Name
FlyBase ID
FBal0007991
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)02047
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} is inserted into an intron of Nipped-B.

Insertion components
P{PZ}Nipped-B02047
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Neuroblast metaphase nuclei show precocious sister chromatid separation in animals heteroallelic for Nipped-B02047 and Nipped-BNC6, Nipped-BNC7, Nipped-BNC23, Nipped-BNC39, Nipped-BNC41, Nipped-BNC59, Nipped-BNC71, Nipped-BNC77 or Nipped-BNC78.

Approximately 60% of metaphase nuclei in the brains of Nipped-B407/Nipped-B02047 second instar larvae show precocious sister chromatid separation, in which the centromeric regions of the sister chromatids are somewhat detached from each other.

50% of metaphase nuclei in the brains of Nipped-B292.1/Nipped-B02047 and Nipped-B02047 homozygous second instar larvae show precocious sister chromatid separation, in which the centromeric regions of the sister chromatids are somewhat detached from each other.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

"FBti0005207 == FBti0000286 == P{PZ}Nipped-B02047" was stated as revision. 9 out of 13 excisions of the P{PZ} revert the Nipped-B mutant phenotype.

Complements: tsh04319. Complements: vlc07022. Complements: l(2)k03002ak03002a. Complements: l(2)k03002ak04601a. Complements: l(2)k07312bk07312b.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (11)