FB2025_01 , released February 20, 2025
Allele: Dmel\spen03350
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General Information
Symbol
Dmel\spen03350
Species
D. melanogaster
Name
FlyBase ID
FBal0008023
Feature type
allele
Associated gene
Dmel\spen
Associated Insertion(s)
P{PZ}spen03350
Carried in Construct
Also Known As
l(2)03350
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}spen03350
Cytology
Description

P{PZ} insertion in the 5' UTR.

(Kuang et al., 2000)

Insertion lies within a 4kb region that represents a hot spot for P-element insertions and maps ~20kb upstream from the Class I cDNA which includes the spen ORF, and immediately upstream of (and slightly overlaps) the j1 cDNA that likely corresponds to the spen 5' UTR.

(Rebay et al., 2000)

Insertion maps in the first intron of the spen transcription unit.

(Wiellette et al., 1999)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Precise excisions of the P{PZ} are viable in combination with spen point mutants, and imprecise excision mutants fail to complement spen point mutants.

      (Wiellette et al., 1999)

      Complements: l(2)04207a04207a. Complements: numb4. Complements: kis07812. Complements: Rpp30k01901. Complements: kisk05630. Complements: kisk08814. Complements: kisk10409. Complements: Hopk14504.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      l(2)03350
      (Rebay et al., 2000, Spradling et al., 1999)
      l(2)0335003350
      (BDGP Project Members, 1994-1999)
      l(2)k03350
      (Kuang et al., 2000)
      spen03350
      (Girard et al., 2020, Eun et al., 2007)
      spenP4
      (Kuang et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (11)