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General Information
Symbol
Dmel\TER9403775
Species
D. melanogaster
Name
FlyBase ID
FBal0008040
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)03775
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion in the 5' non-coding region.

Insertion in the 5' UTR of TER94. Site of insertion in TER94k15502 and TER9403775 are identical.

P{PZ} insertion in the 5' untranslated region.

Insertion components
P{PZ}TER9403775
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Female germ-line clones do not produce germaria or egg chambers. TER9403775 mutant egg chambers have abnormal endoplasmic reticulum. DiO-C6 staining is weaker and more particulate than seen in wildtype. The fusome is wild-type in these embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

TER9403775 has neuroanatomy defective phenotype, enhanceable by TER94[+]/TER94k15502

Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

TER9403775/TER94[+] is an enhancer of eye phenotype of Scer\GAL4GMR.PS, cazVDRC.cUa

TER9403775/TER94[+] is an enhancer of ommatidium phenotype of Scer\GAL4GMR.PS, cazVDRC.cUa

Suppressor of
Statement
Reference

TER9403775/TER94[+] is a suppressor | partially of eye phenotype of Scer\GAL4ey.PH, atlUAS.Tag:MYC

TER9403775/TER94[+] is a suppressor | partially of eye phenotype of Zzzz\CAGQ92.GMR.Tag:FLAG

Additional Comments
Genetic Interactions
Statement
Reference

Heterozygous TER9403775 enhances the rough-eye phenotype induced by Scer\GAL4GMR.PS>cazVDRC.cUa.

The small eye phenotype characteristic for adult flies expressing atlScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF is significantly ameliorated by combination with a single copy of TER9403775.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

Phenotypic analysis suggests an allelic series, starting from the strongest: TER94k15502, TER9426-8, TER9403775, TER9422-30, TER9414-23, TER9422-26, TER947-12 and TER9443-8.

After six generations of outcrossing the lethality continued to segragate with the P{PZ} insertion.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (13)