FlyBase Allele Report: Dmel\Cam[03909]

General Information

Symbol

Dmel\Cam⁰³⁹⁰⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0008045

Feature type

allele

Associated gene

Dmel\Cam

Associated Insertion(s)

P{PZ}Cam⁰³⁹⁰⁹

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}Cam⁰³⁹⁰⁹

Cytology

Description

P{PZ} insertion maps 60bp 5' to the transcription start site.

(Harvie et al., 1998)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:12,259,351..12,259,351 [+]

(Spradling et al., 1999, Harvie et al., 1998, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AF006643

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates myopathy

modeled by Hsap\MYBPC3^UAS.Tag:MYC

(Manh et al., 2005)

modeled by Hsap\MYBPC3^{M6.UAS.Tag:MYC}

(Manh et al., 2005)

modeled by Hsap\MYBPC3^{M0.UAS.Tag:MYC}

(Manh et al., 2005)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | larval stage (with Camⁿ³³⁹)

(Wang et al., 2003)

lethal | recessive

(Spradling et al., 1999, Harvie et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

The amount of backward movement seen in Cam⁰³⁹⁰⁹/Camⁿ³³⁹ larvae is increased by high light intensity.

(Wang et al., 2003)

Shows an extended third instar phenotype.

(Harvie et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Cam[+]/Cam⁰³⁹⁰⁹ is a suppressor | partially of flightless phenotype of Hsap\MYBPC3^UAS.Tag:MYC, Scer\GAL4^sd-SG29.1

(Manh et al., 2005)

Cam[+]/Cam⁰³⁹⁰⁹ is a suppressor | partially of flightless phenotype of Hsap\MYBPC3^{M6.UAS.Tag:MYC}, Scer\GAL4^sd-SG29.1

(Manh et al., 2005)

Cam[+]/Cam⁰³⁹⁰⁹ is a suppressor | partially of flightless phenotype of Hsap\MYBPC3^{M0.UAS.Tag:MYC}, Scer\GAL4^sd-SG29.1

(Manh et al., 2005)

Other

Statement

Reference

Cam⁰³⁹⁰⁹, scrib[+]/scrib^smi97B has abnormal smell perception | dominant | male phenotype

(Anholt et al., 2003)

Cam⁰³⁹⁰⁹, scrib^smi97B has abnormal smell perception | dominant | male phenotype

(Anholt et al., 2003)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Heterozygosity for Cam⁰³⁹⁰⁹ partially rescues the flightless phenotype caused by expression of either Hsap\MYBPC3^{Scer\UAS.T:Hsap\MYC}, Hsap\MYBPC3^{M6.Scer\UAS.T:Hsap\MYC} or Hsap\MYBPC3^{M0.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^sd-SG29.1.

(Manh et al., 2005)

Complementation and Rescue Data

Complements

Cam^k11802

(BDGP Project Members, 1994-1999)

Fails to complement

Cam⁰⁶³⁷²

(BDGP Project Members, 1994-1999)

Cam⁰²⁸²⁸

(BDGP Project Members, 1994-1999)

Cam^k04213

(BDGP Project Members, 1994-1999)

Cam^k09510

(BDGP Project Members, 1994-1999)

Cam^k09533

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11356

w¹¹¹⁸; cn¹ P{PZ}Cam⁰³⁹⁰⁹/CyO, P{sevRas1.V12}FK1

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: SmD3⁰²⁸³³. Complements: Cct5⁰⁶⁴⁴⁴. Complements: Cct5^k06005. Complements: Cct5^k09720. Complements: l(2)k11404^k11404.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF006643

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Cam⁰³⁹⁰⁹

(Manh et al., 2005)

Cam³⁹⁰⁹

(Wang et al., 2003)

l(2)03909

(Spradling et al., 1999)

l(2)03909⁰³⁹⁰⁹

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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