FlyBase Allele Report: Dmel\capt[06955]

General Information

Symbol

Dmel\capt⁰⁶⁹⁵⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0008122

Feature type

allele

Associated gene

Dmel\capt

Associated Insertion(s)

P{PZ}capt⁰⁶⁹⁵⁵

Carried in Construct

Also Known As

l(2)06955

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}capt⁰⁶⁹⁵⁵

Cytology

Description

P{PZ} insertion in the first intron, downstream of an untranslated 85bp exon.

(Benlali et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:1,157,958..1,157,958 [+]

(Benlali et al., 2000, Baum, 1999.9.26, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile

(Perrimon et al., 1996)

lethal | recessive

(Spradling et al., 1999)

lethal - all die before end of larval stage | recessive

(Perrimon et al., 1996)

some die during larval stage | recessive

(Perrimon et al., 1996)

Phenotype Manifest In

egg | germline clone

(Perrimon et al., 1996)

oocyte & actin filament | ectopic | germ-line clone

(Baum et al., 2000)

ovariole | germline clone

(Perrimon et al., 1996)

Detailed Description

Statement

Reference

Ectopic actin filaments first form at the posterior of the oocyte at stage 5-6 in capt¹⁰ germ-line clones.

(Baum et al., 2000)

Germline clones produce abnormal eggs due to abnormal oogenesis: misshapen eggs.

(Perrimon et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

capt⁰⁶⁹⁵⁵ is an enhancer of abnormal cell polarity phenotype of S^48-5

(Gaengel and Mlodzik, 2003)

Other

Statement

Reference

Abl^unspecified, capt[+]/capt⁰⁶⁹⁵⁵ has abnormal neuroanatomy phenotype

(Wills et al., 2002)

Df(2L)ast5, capt⁰⁶⁹⁵⁵ has abnormal neuroanatomy phenotype

(Wills et al., 2002)

Abl^unspecified, capt⁰⁶⁹⁵⁵ has abnormal neuroanatomy phenotype

(Wills et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

capt⁰⁶⁹⁵⁵ is an enhancer of ommatidium phenotype of S^48-5

(Gaengel and Mlodzik, 2003)

Other

Statement

Reference

Abl^unspecified, capt[+]/capt⁰⁶⁹⁵⁵ has presumptive embryonic/larval central nervous system phenotype

(Wills et al., 2002)

Df(2L)ast5, capt⁰⁶⁹⁵⁵ has presumptive embryonic/larval central nervous system phenotype

(Wills et al., 2002)

Abl^unspecified, capt⁰⁶⁹⁵⁵ has presumptive embryonic/larval central nervous system phenotype

(Wills et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

S^48-5/capt⁰⁶⁹⁵⁵ mutants show 34.19%+-8.94 misrotated ommatidia compared to 9.55%+-1.43 seen in S^48-5 mutants alone.

(Gaengel and Mlodzik, 2003)

Central nervous system axons are seen to cross the midline in Abl^unspecified capt⁰⁶⁹⁵⁵ double heterozygous embryos. capt⁰⁶⁹⁵⁵/Df(2L)ast5 embryos show 71% ectopic midline crossing by axons in the central nervous system.

(Wills et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

capt^k01217

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

12330

cn¹ P{PZ}capt⁰⁶⁹⁵⁵/CyO; ry⁵⁰⁶

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: Tango14^k00619.

(Levis and Spradling, 2001.8.14)

Complements: Tango14^k00619. Complements: l(2)01855⁰¹⁸⁵⁵. Complements: l(2)04111⁰⁴¹¹¹. Complements: dock⁰⁴⁷²³. Complements: S⁰⁷⁰⁵⁶. Complements: l(2)10685¹⁰⁶⁸⁵. Complements: dbe^k00108. Complements: l(2)10685^k00420. Complements: l(2)10685^k05810. Complements: dbe^k06708. Complements: l(2)k11325^k11325. Complements: RFeSP^k11704.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

P2330

(Baum, 1999.9.26)

P3605

(Wills et al., 2002)

cap¹

(Baum et al., 2000)

capt-06955

(Gaengel and Mlodzik, 2003)

capt⁰⁶⁹⁵⁵

(Christensen et al., 2008.4.15, Medina et al., 2008)

capt¹

(Wills et al., 2002)

capulet⁰⁶⁹⁵⁵

l(2)06955

(Benlali et al., 2000, Spradling et al., 1999)

l(2)06955⁰⁶⁹⁵⁵

(Perrimon et al., 1996, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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