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General Information
Symbol
Dmel\YetiEMS-31
Species
D. melanogaster
Name
FlyBase ID
FBal0008961
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EMS31
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

A1344770T

Reported nucleotide change:

A316T

Amino acid change:

K106term | Yeti-PA; K106term | Yeti-PB

Reported amino acid change:

K106term

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: A316T.

Amino acid replacement: K106term.

Point mutation.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The total number of Df(2R)B/l(2)41Aa1 larval neuroblast cells undergoing mitosis is reduced compared to wild-type cells (mitotic index of 0.2 vs 0.81). The number of l(2)41AaIR18/l(2)41Aa1 cells undergoing mitosis is likewise reduced (mitotic index of 0.5). 10% of l(2)41AaIR18/l(2)41Aa1 mutant larval spermatids carry micronuclei. 4% of l(2)41AaIR18/l(2)41Aa1 mutant larval spermatids have large Nebenkerns associated with either two or four nuclei or micronuclei. In 10% of l(2)41AaIR18/l(2)41Aa1 mutant larval spermatids, bivalents do not condense properly and chromatin filaments are visible along the three major dots of chromatin. In l(2)41AaIR18/l(2)41Aa1 mutant larval spermatids, 15% of chromosomes are seen to be lagging during anaphase/telophase I and 14% lag during anaphase/telophase II.

In heterozygous combination with Df(2R)B dies as late third instar larvae exhibiting one or more large and numerous small melanotic masses in the hemocoel.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
YetiEMS-31
l(2)41Aa1
l(2)EMS-31
Name Synonyms
Secondary FlyBase IDs
    References (5)