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General Information
Symbol
Dmel\bunrI043
Species
D. melanogaster
Name
FlyBase ID
FBal0009292
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{PZ}bunrI043
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

bunrI043/bunout14, bunrI043/bunout4 and bunrI043/bunout12 escapers have slightly bent legs and defects in wing venation.

94% of eggs laid by homozygous females have minor defects in the dorsal appendages. 85% of eggs have an altered operculum which is expanded posteriorly and ventrally. Every eggshell with an enlarged operculum is also missing the collar structure at the operculum edge and the boundary between operculum imprints and mainbody imprints is rotated ventrally.

Homozygous somatic clones in the ovaries produce defective eggs that are small and infertile, with short dorsal appendages that are variably rounded with branched split ends (approximately 5% of eggs laid by bunrI043 females 2-3 days following homozygous clone induction have this phenotype).

Semilethal; homozygous escapers have slightly small, rough eyes, the roughness is predominantly due to missing photoreceptors. In the heads of adult homozygotes the R7 and R8 axons often project anteriorly relative to their wild type position. This phenotype reflects the failure of the medulla to undergo its normal developmental rotation between 39 and 48 hours of pupal development. Homozygous escapers exhibit loss of parts of the wing margin.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

bunrI043 has eye phenotype, enhanceable by S05671

bunrI043 has eye phenotype, enhanceable by hhrJ413

Suppressed by
Statement
Reference

bunrI043 has phenotype, suppressible by aopyan-1

Additional Comments
Genetic Interactions
Statement
Reference

Mutant phenotype is enhanced by S05671 or loss of one copy of hh (eye becomes smaller and rougher) and suppressed by aopyan-1 or loss of one copy of wg (restored to wild type). Double mutants of bunrI043 and the eye specific allele hhbar3 all die as pupae, although hhbar3 itself is viable. In double mutants of bunrI043 and the eye specific allele dppd-blk the frequency of survivors is decreased relative to the single bunrI043 mutant and the eye is extremely reduced due to differentiation of a very small number of ommatidia. The third instar larval eye imaginal disc exhibits a delay in neuronal differentiation relative to the morphogenetic furrow.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

G. Rubin.

Comments
Comments

Complements: l(2)0181001810. Complements: Aats-thrk04910. Complements: aret01284.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
  • FBal0045412
References (10)