mutant clones in sensory neurons in adult wing do not display any defects in injury-induced axon degeneration (following an axotomy, the severed axons are cleared away normally).
Third larval instar discs are overgrown in mosaic animals. Adults containing homozygous clones have overgrown eyes.
mutants fail to efficiently sever their larval dendrites during metamorphosis, with the retention of approximately 45% of large dendritic branches at 20 hours after pupal formation.
Mutant neuroblast clones show grossly normal axonal projections to both the dorsal and medial lobes. However there are fewer cells in mutant clones as compared to wild-type. Pruning defects are evident at 18h after puparium formation (APF) indicated by the persistence of continuous larval branches. Dendrite pruning is also inhibited in clones. Although mutant mushroom body neurons survive into adulthood more than 10 days after clone induction, abnormal morphology of axons is clearly visible.